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中文摘要
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摘要 白血病MSK孢子致力于支持有才华的研究人员的持续发展 他们正在进行白血病的独立转化研究项目。职业提升 计划(CEP)将提供研究奖励,以支持1)初级教师的学术发展, 基础或临床研究背景,从事与预防,诊断和治疗相关的研究 白血病; 2)新的或建立的教师在其他学科领域谁希望获得额外的培训, 经验,这将使他们能够解决与白血病研究相关的未满足的需求领域;和3)高级 博士后研究员谁将继续他们的研究计划在白血病和谁是在一年内的一个 教师任命。孢子PI,奥马尔阿卜杜勒瓦哈卜博士和马丁塔尔曼,将监督该计划 每个人都为CEP带来了基础、临床和转化科学方面的大量知识和专业知识 活动我们每年将招募最多两名合格的研究人员接受CEP资助, 第二年续约。候选人可由SPORE执行委员会成员推荐, 项目负责人/核心董事、内部咨询委员会或根据合作伙伴的建议 个人在适当的时候。为了鼓励申请人的科学和社会多样性,我们还将 联系外部已建立的研究网络,并每年发布研究资助公告(RFA), 跨三机构地区的研究部门(MSK,威尔康奈尔医学院,洛克菲勒 大学)。我们将考虑从事研究的候选人,包括但不限于细胞生物学, 计算生物学,实验治疗学,分子生物学,遗传学,免疫学,血液学, 肿瘤学、病理学和医学信息学。申请人也将被评估他们的研究计划 作为职业发展计划,与建议的导师协调编写。成功得奖者将获得 每月评估他们的研究进展和职业发展里程碑。CEP是 致力于支持我们的白血病研究教师之间的多样性,并将密切合作, 该机构的多样性方案办公室,以促进妇女和代表性不足的职业发展 在我们的医疗保健研究界的种族和民族群体。
英文摘要
ABSTRACT The MSK SPORE in Leukemia is dedicated to supporting the ongoing development of talented researchers who are pursuing independent translational research programs in leukemia. The Career Enhancement Program (CEP) will provide research awards to support the scholarly development of 1) junior faculty from basic or clinical research backgrounds pursuing research related to the prevention, diagnosis and treatment of leukemia; 2) new or established faculty in other subject areas who wish to attain additional training and experience that will allow them to address areas of unmet need related to leukemia research; and 3) senior postdoctoral fellows who will continue their research program in leukemia and who are within one year of a faculty appointment. The SPORE PIs, Drs. Omar Abdel-Wahab and Martin Tallman, will oversee the program and each brings considerable knowledge and expertise in basic, clinical, and translational science to CEP activities. We will recruit up to two qualified investigators per year to receive CEP funding, with possibility of renewal for a second year. Candidates may be suggested by members of the SPORE Executive Committee, Project Leaders/Core Directors, the Internal Advisory Board, or at the recommendation of collaborating individuals where appropriate. To encourage scientific and social diversity among our applicants, we will also reach outside established research networks and issue a Research Funding Announcement (RFA) annually to research departments across the Tri-institutional area (MSK, Weill Cornell Medical College, Rockefeller University). We will consider candidates pursuing research including but not limited to cell biology, computational biology, experimental therapeutics, molecular biology, genetics, immunology, hematology, oncology, pathology, and medical informatics. Applicants will be evaluated on their research proposal as well as a career development plan, written in coordination with a proposed mentor. Successful awardees will be evaluated monthly on their research progress and career development milestones achieved. The CEP is committed to supporting diversity among our leukemia research faculty and will work closely with the institution's Office of Diversity Programs to promote the career advancement of women and underrepresented racial and ethnic groups in our healthcare research community.
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Synthetic introns for selective targeting of RNA splicing factor-mutant leukemia
  • 批准号:
    10722782
  • 项目类别:
  • 资助金额:
    $74.86万
  • 财政年份:
    2023
  • 负责人:
    Omar Abdel-Wahab
  • 依托单位:
Charting the differentiation topology of SF3B1 mutated clonal hematopoiesis (CH) and myelodysplastic syndromes (MDS) via a multi-omics single-cell toolkit
Charting the differentiation topology of SF3B1 mutated clonal hematopoiesis (CH) and myelodysplastic syndromes (MDS) via a multi-omics single-cell toolkit
Project 3: Therapeutic inhibition of splicing through inhibition of protein arginine methylation in leukemia
  • 批准号:
    10474285
  • 项目类别:
  • 资助金额:
    $36.77万
  • 财政年份:
    2021
  • 负责人:
    Omar Abdel-Wahab
  • 依托单位:
海外基金