Roybal Center Pilot Core

Pilot核心概述：Duke Roybal Pilot核心的目标是可测量地推进和加速 通过支持高质量的先导性研究，对衰老和行动能力进行行为干预研究 跨阶段模型各层次的研究进展。试点核心计划的目标是： 1)评估并吸引研究人员建立必要的技能，以制定符合以下条件的行为干预措施 对于行动相关活动受限的风险较大或有活动受限的老年人来说，这两种方法都是有效和可实施的。 2)使用新的项目管理加速器模式，每年促进2-4个中心资助的项目 和持续的性能改进技术，以优化研究效率。 3)促进翻译并促进整个杜克大学的试点计划协同效应，最大限度地提高影响和 传播由该中心支持的干预发展研究。 我们将从杜克大学和合作机构征集和选择高质量的试点研究，使用 严格的多阶段流程，包括内部和外部意向通知、建议书指导 对选定的试点研究进行审查，并提供强有力的团队支持、管理和监测。我们将资助一年期 具有明确定义的可交付成果和产出的飞行员，从而达到阶段模型中的下一个适当水平。我们 将为每位试点获奖者提供第二年的项目管理支持，以确保翻译和 根据初步调查结果，协助为较大的拨款提案制定提案。 为了实现我们的目标，Duke Roybal Pilot Core包括几个高度创新的功能： I.直接访问中心领导层、合作调查员、资源、培训和合作伙伴。 二、一个拥有高级项目管理支持的实施团队，以促进在 团队科学，确保达到里程碑，加快研究生产率和翻译速度。 三、在没有资金的申请者中支持有前途的干预者的科学和职业生涯的机制。 每年将资助两到四个试点项目。第一年选定的两个试点项目包括 旨在开发和测试体育活动的可行性、可接受性和初步效果的研究 心力衰竭老年人社区居住技能培训手册。第二项研究将发展和 为老年肺癌患者测试一种简短的结构化自我系统治疗干预措施。这两项研究的目的都是 改善身体功能、自我效能和生活质量以及其他相关结果。 Roybal Pilot Core将以可测量和加速的方式影响行为干预和老龄化研究 科学成果。该核心将通过支持和开展试点研究，对公共卫生作出重大贡献 为高危老年人开发和完善保持或恢复活动能力的新方法，通过将理论- 基于经验验证的行为干预策略，以影响相关结果。在指导下 根据NIH阶段模型，Pilot Core将生成可导致高影响研究的初步数据。

PILOT CORE SUMMARY: The goal of the Duke Roybal Pilot Core is to measurably advance and accelerate behavioral intervention research on aging and mobility by supporting high quality pilot studies that inform research progression across the levels of the Stage Model. The Pilot Core aims to: 1) Assess and engage researchers to build the skills necessary to develop behavioral interventions that are both effective and implementable for older adults at-risk for or with mobility-related activity limitations. 2) Facilitate 2-4 Center-funded projects per year, using a novel accelerator model for project management and continuous performance improvement techniques to optimize research efficiency. 3) Catalyze translation and foster pilot program synergies across Duke, maximizing the impact and dissemination of the intervention development research supported by the Center. We will solicit and select high quality pilot studies from across Duke University and partnering institutions using a rigorous, multi-stage process that incorporates a notice of intent, proposal guidance, internal and external review, and intense team support, management and monitoring for selected pilot studies. We will fund 1-year pilots with clearly defined deliverables and outputs leading to the next appropriate level in the Stage Model. We will provide each pilot awardee a second year of project management support to ensure translation and to assist in proposal development for larger grant proposals based on initial findings. To accomplish our Aims, the Duke Roybal Pilot Core includes several highly innovative features: i. Direct access to Center leadership, co-investigators, resources, training, and collaborating partners. ii. An implementation team with high level project management support to facilitate experiential learning in team science, ensure milestones are met and research productivity and translation are accelerated. iii. Mechanisms that support the science and careers of promising interventionists amid unfunded applicants. Two to four pilot projects will be funded per year. The two pilot projects selected for the first year include a study designed to develop and test the feasibility, acceptability, and preliminary effects of a physical activity skills training manual for community dwelling older adults with heart failure. The second study will develop and test a brief structured self-system therapy intervention for older adults with lung cancer. Both studies aim to improve physical function, self-efficacy, and quality of life among other relevant outcomes. The Roybal Pilot Core will impact behavioral intervention and aging research with measurable and accelerated scientific output. The core will contribute significantly to public health by supporting and conducting pilot studies that develop and refine new ways for at-risk older adults to maintain or recover mobility, by bringing theory- based, empirically validated behavioral intervention strategies to bear on relevant outcomes. Guided by the NIH Stage Model, the Pilot Core will generate preliminary data that can lead to high-impact studies.