Roybal Center Pilot Core

试点核心摘要：杜克Roybal试点核心的目标是可测量地推进和加速 通过支持高质量的试点研究，对老龄化和流动性进行行为干预研究， 跨阶段模型水平的研究进展。试点核心旨在： 1)评估和参与研究人员建立必要的技能，以制定行为干预措施， 对于有活动受限风险或具有活动受限的老年人来说，这两种方法都是有效且可实施的。 2)每年促进2-4个中心资助的项目，使用新的加速器模式进行项目管理 和持续的性能改进技术，以优化研究效率。 3)促进翻译并促进整个杜克试点项目的协同作用，最大限度地提高影响力， 传播中心支持的干预发展研究。 我们将征求和选择高质量的试点研究，从整个杜克大学和合作机构使用 这是一个严格的多阶段过程，包括意向通知、提案指南、内部和外部 对选定的试点研究进行审查和密集的团队支持、管理和监测。我们将资助1年 具有明确定义的可交付成果和输出的试点项目，可通向阶段模型中的下一个适当级别。我们 将为每个试点获奖者提供第二年的项目管理支持，以确保翻译和 根据初步调查结果，协助制定更大规模的赠款提案。 为了实现我们的目标，杜克Roybal Pilot Core包括几个高度创新的功能： I.直接访问中心领导层、合作研究者、资源、培训和合作伙伴。 二.一个具有高水平项目管理支持的实施团队，以促进以下方面的经验学习： 团队科学，确保达到里程碑，加快研究生产力和翻译。 三.在没有资金的申请者中支持有前途的干预者的科学和职业的机制。 每年将资助两至四个试点项目。第一年选定的两个试点项目包括 为开发和测试一项体育活动的可行性、可接受性和初步效果而设计的研究 社区居住的老年心力衰竭患者技能培训手册。第二项研究将发展和 测试一个简短的结构化自我系统治疗干预老年人肺癌。这两项研究旨在 改善身体功能、自我效能和生活质量以及其他相关结果。 Roybal Pilot Core将以可衡量和加速的方式影响行为干预和衰老研究。 科学产出。该核心将通过支持和开展试点研究，为公共卫生做出重大贡献 开发和完善新的方法，为处于危险中的老年人保持或恢复流动性，通过带来理论- 基于经验验证的行为干预策略，以影响相关结果。为指导 NIH阶段模型，试点核心将产生初步数据，可以导致高影响力的研究。

PILOT CORE SUMMARY: The goal of the Duke Roybal Pilot Core is to measurably advance and accelerate behavioral intervention research on aging and mobility by supporting high quality pilot studies that inform research progression across the levels of the Stage Model. The Pilot Core aims to: 1) Assess and engage researchers to build the skills necessary to develop behavioral interventions that are both effective and implementable for older adults at-risk for or with mobility-related activity limitations. 2) Facilitate 2-4 Center-funded projects per year, using a novel accelerator model for project management and continuous performance improvement techniques to optimize research efficiency. 3) Catalyze translation and foster pilot program synergies across Duke, maximizing the impact and dissemination of the intervention development research supported by the Center. We will solicit and select high quality pilot studies from across Duke University and partnering institutions using a rigorous, multi-stage process that incorporates a notice of intent, proposal guidance, internal and external review, and intense team support, management and monitoring for selected pilot studies. We will fund 1-year pilots with clearly defined deliverables and outputs leading to the next appropriate level in the Stage Model. We will provide each pilot awardee a second year of project management support to ensure translation and to assist in proposal development for larger grant proposals based on initial findings. To accomplish our Aims, the Duke Roybal Pilot Core includes several highly innovative features: i. Direct access to Center leadership, co-investigators, resources, training, and collaborating partners. ii. An implementation team with high level project management support to facilitate experiential learning in team science, ensure milestones are met and research productivity and translation are accelerated. iii. Mechanisms that support the science and careers of promising interventionists amid unfunded applicants. Two to four pilot projects will be funded per year. The two pilot projects selected for the first year include a study designed to develop and test the feasibility, acceptability, and preliminary effects of a physical activity skills training manual for community dwelling older adults with heart failure. The second study will develop and test a brief structured self-system therapy intervention for older adults with lung cancer. Both studies aim to improve physical function, self-efficacy, and quality of life among other relevant outcomes. The Roybal Pilot Core will impact behavioral intervention and aging research with measurable and accelerated scientific output. The core will contribute significantly to public health by supporting and conducting pilot studies that develop and refine new ways for at-risk older adults to maintain or recover mobility, by bringing theory- based, empirically validated behavioral intervention strategies to bear on relevant outcomes. Guided by the NIH Stage Model, the Pilot Core will generate preliminary data that can lead to high-impact studies.