Huntsman Cancer Institute PathMaker Programs for Cancer Research

此R25应用程序的首要目标是增强个人池的多样性， 有兴趣从事生物医学和癌症相关研究的代表性不足的群体， 为高中和本科生提供研究经验，研究和课程 初中和高中科学教师的发展经验，以及对中学的推广 学生，他们的家庭和社区。亨斯迈癌症研究所PathMaker项目 癌症研究将带来特殊的癌症研究培训管道计划，犹他州和山区 西支持国家癌症研究所的R25计划的目标，增加生物医学， 行为学和临床研究人员。拟议的计划，建立在成功的P30 CURE和 FRTEP补充，将包括三个相互关联和互补的组成部分：PathMaker学者， PathMaker Bridge和PathMaker Connect。PathMaker Scholars是一个有指导的癌症研究体验 为高中生和本科生; PathMaker Bridge提供指导性癌症研究 经验和指导课程开发的初中和高中科学教师，提供了一个 与学生建立联系;使用PathMaker Connect，我们将连接HCI和前面提到的两个 通过创新的外展活动，向特定的社区提供服务。虽然来自所有团体的申请人 在生物医学研究中代表性不足将受到鼓励和欢迎，招聘工作将集中在 属于对犹他州和湖城重要的三个少数民族之一的学生：西班牙裔/拉丁裔， 美洲印第安人或阿拉斯加原住民，或夏威夷原住民或太平洋岛民。西班牙裔/拉丁裔构成了犹他州的 少数民族人口最多，占总人口的14%，18岁以下人口的近18% 年龄。此外，犹他州是八个美洲印第安部落或民族的家园，还有一个令人惊讶的大太平洋岛民 人口包括四分之一的汤加裔美国人。这些群体在非洲的代表性严重不足， 他们面临着与癌症相关的健康差距。该项目将由一名 团队由一名医生科学家和一名基础科学家组成，他们在项目方面具有相关经验， 增加生物医学研究职业、职业指导和生物医学研究职业培训的多样性。 学生的研究经验将通过丰富的专业准备和社区建设得到加强 程序.此外，PathMaker Bridge还将与国际知名的犹他州大学合作 遗传科学学习中心（GSLC）提供卓越的专业发展计划， 指导教师参与者利用他们的研究经验来创建新的课程材料， 有可能在GSLC网站上向全世界传播。专业评估人员将提供形成性的 和总结性评估，以确保该计划实现其最大潜力。

The overarching goal of this R25 application is to enhance the diversity of the pool of individuals from underrepresented groups interested in pursuing careers in biomedical and cancer-related research by providing research experiences for high school and undergraduate students, research and curriculum development experiences for middle and high school science teachers, and outreach to middle school students, their families, and their communities. The Huntsman Cancer Institute PathMaker Programs for Cancer Research will bring exceptional cancer research training pipeline programs to Utah and the Mountain West to support the National Cancer Institute’s R25 program goal of increasing diversity of the biomedical, behavioral, and clinical research workforce. The proposed program, building on successful P30 CURE and FRTEP Supplements, will comprise three interrelated and complementary components: PathMaker Scholars, PathMaker Bridge, and PathMaker Connect. PathMaker Scholars is a mentored cancer research experience for high school and undergraduate students; PathMaker Bridge provides mentored cancer research experiences and guided curriculum development for middle and high school science teachers, providing a bridge to their students; with PathMaker Connect we will connect HCI and the two previously-mentioned groups to a specific community through an innovative outreach event. While applicants from all groups underrepresented in biomedical research will be encouraged and welcomed, recruiting efforts will focus on students who belong to one of three minority groups significant to Utah and Salt Lake City: Hispanic/Latino, American Indian or Alaska Native, or Native Hawaiian or Pacific Islander. Hispanic/Latinos comprise Utah’s largest minority population, with 14% of the overall population and nearly 18% of the population under 18 years of age. Also, Utah is home to eight American Indian tribes or nations, and a surprisingly large Pacific Islander population including one-fourth of all Tongan Americans. These groups are massively underrepresented in biomedical research, and they face significant cancer-related health disparities. This project will be led by a team comprising a physician scientist and a basic scientist, who have relevant experience in programs to increase diversity in biomedical research careers, career mentoring, and biomedical research career training. Student research experiences will be enhanced by a rich professional preparation and community-building program. Additionally, PathMaker Bridge will partner with the internationally-recognized University of Utah Genetic Science Learning Center (GSLC) to provide an exceptional professional development program to guide teacher participants in using their research experiences to create novel curricular materials, with the potential for world-wide dissemination on the GSLC website. A professional evaluator will provide formative and summative evaluation to ensure the program achieves its maximum potential.