Research Education Component
研究教育部分
基本信息
- 批准号:10475322
- 负责人:
- 金额:$ 25.84万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2021
- 资助国家:美国
- 起止时间:2021-09-01 至 2026-06-30
- 项目状态:未结题
- 来源:
- 关键词:AddressAgingAlzheimer&aposs DiseaseAlzheimer&aposs disease related dementiaAmericanAmerican IndiansBasic ScienceBiological MarkersBiology of AgingCapsicumClinicClinicalClinical InvestigatorClinical ResearchCollaborationsCommunicationCommunity DevelopmentsDevelopmentDisciplineDoctor of PhilosophyEducational CurriculumEducational workshopEnvironmentExposure toFaceFacultyFosteringFoundationsFutureGoalsHealthHistorically Black Colleges and UniversitiesInstitutionJournalsKnowledgeLearningLongevityManuscriptsMediatingMedicalMedical ResearchMedical StudentsMentorsMentorshipNeurosciencesNorth CarolinaOutcomePathologicPathologyPatient RecruitmentsPopulationPositioning AttributePostdoctoral FellowPreventive measureResearchResearch DesignResearch EthicsResearch PersonnelResearch SupportResearch TrainingResourcesSamplingScienceScientistSiteSpecimenStatistical Data InterpretationStudentsTalentsTrainingTraining ProgramsTraining and EducationTranslational ResearchUnderserved PopulationUniversitiesage relatedbasebiobankcareerdisparity reductioneducation researchexperiencehealth care deliveryimprovedinnovationinsightinterdisciplinary collaborationinterestmedical specialtiesmultidisciplinarynext generationnovelonline coursepostersprogramsresearch data disseminationresponsible research conductrural healthcaresummer researchsymposiumtargeted deliverytraining opportunity
项目摘要
ABSTRACT - Research Education Component
The primary goal of the Duke/UNC Alzheimer’s Disease Research Center (ADRC) Research Education
Component (REC) is to develop future leaders in Alzheimer’s disease (AD) and AD-related dementias
(AD+ADRD) research, including within the Center’s theme of identifying age-related changes across the lifespan
that mediate the development, progression and experience of AD. There are unique challenges facing
AD+ADRD research, including limited training in researchprinciples, a lack of early-career exposure to
AD+ADRD research, and research silos that impede knowledge transfer between basic and clinical investigators.
To overcome these challenges, the REC research training program will broadly disseminate a foundational
AD+ADRD research curriculum spanning both basic and clinical research, delivered to five universities across
North Carolina and made available to the public (Aim 1). In addition to delivering broad cross-campus AD+ADRD
research education, the REC will solicit “REC Scholar” applications and select 2-4 scholars annually from a
diverse pool of talented early-career AD+ADRD investigators (Aim 2). REC Scholars will receive intensive
research training and tailored professional development under the guidance of a faculty mentorship team
comprised of a clinical researcher and a basic scientist. The REC will expand the reach of its training program
by leveraging existing training assets at Duke and UNC (e.g., Duke’s “Creating AD Researchers for the Next
Generation” STARR Program (R38), UNC’s “Summer Research Training in Aging for Medical Students” (T35)
and Duke’s Claude D. Pepper Older Americans Independence Center and Edward R. Roybal Center). The
REC’s close integration with the other Duke/UNC ADRC cores provides synergistic interactions with key
research training opportunities in specimen biobanking, statistical analysis, study design, pathologic sample
analysis, patient recruitment, and research dissemination. The REC will diversify AD+ADRD researcher
perspectives and the workforce by partnering with UNC Pembroke (a designated historically American Indian
university), NC Central University (an historically black university), and East Carolina University (an institution
with expertise in rural healthcare delivery) (Aim 3). Investigators and trainees at these institutions will participate
in monthly research colloquia, the online curriculum, monthly journal clubs, research consultancies that leverage
Duke/UNC expertise to augment AD+ADRD research at other sites, and the annual Symposium for Learning
about Alzheimer’s disease-related Medical research at Duke and UNC (SLAM-DUNC), hosted by each institution
in turn. REC programming will foster interest in AD+ADRD research and cultivate the multidisciplinary expertise
needed in its next generation of leaders. By fostering interactions among investigators from different disciplines
and backgrounds through the REC’s innovative and inclusive programming, the REC will develop new
AD+ADRD researchers prepared to engage in interdisciplinary collaborations aimed at improving health
outcomes and reducing disparities by bringing novel treatments to the clinic and novel preventive measures to
the population.
摘要-研究教育部分
杜克/杜克阿尔茨海默病研究中心(ADRC)研究教育的主要目标
组成部分(REC)是发展阿尔茨海默病(AD)和AD相关痴呆症的未来领导者
(AD+ADRD)研究,包括该中心的主题,即确定整个生命周期中与年龄相关的变化
介导AD的发生、进展和经历。我们面临着独特的挑战
AD+ADRD研究,包括研究原则的培训有限,缺乏早期职业接触,
AD+ADRD研究,以及阻碍基础和临床研究者之间知识转移的研究孤岛。
为了克服这些挑战,REC研究培训计划将广泛传播一个基本的
AD+ADRD研究课程涵盖基础和临床研究,提供给五所大学,
北卡罗来纳州,并提供给公众(目标1)。除了提供广泛的跨校园AD+ADRD
研究教育,REC将征求“REC学者”的申请,并选择2-4学者每年从一个
多样化的有才华的早期职业AD+ADRD研究者库(目标2)。REC学者将获得密集的
在教师指导团队的指导下进行研究培训和量身定制的专业发展
由一名临床研究员和一名基础科学家组成。REC将扩大其培训计划的范围
通过利用杜克和杜克大学的现有培训资产(例如,杜克的“为下一代创造广告研究人员”
一代”STARR计划(R38),ESTA的“夏季研究培训医学生老龄化”(T35)
还有杜克的克劳德·D佩珀老年美国人独立中心和爱德华R。Roybal Center)。的
REC与其他杜克/杜克ADRC核心的紧密集成提供了与关键
标本生物库、统计分析、研究设计、病理样本方面的研究培训机会
分析、患者招募和研究传播。REC将使AD+ADRD研究人员多样化
观点和劳动力的合作,与彭布罗克(一个指定的历史上美国印第安人
大学),北卡罗来纳中央大学(一所历史悠久的黑人大学)和东卡罗莱纳大学(一所机构
(三)农村医疗卫生服务(目标3)。这些机构的调查人员和受训人员将参加
在每月的研究座谈会,在线课程,每月的期刊俱乐部,研究咨询,
杜克/杜克大学的专业知识,以增加在其他网站的AD+ADRD研究,以及年度研讨会的学习
关于阿尔茨海默病相关的医学研究在杜克和杜克大学(SLAM-DUNK),由每个机构主办
依次REC计划将培养对AD+ADRD研究的兴趣,并培养多学科的专业知识
需要下一代领导人。通过促进不同学科研究者之间的互动,
通过REC的创新和包容性规划,REC将开发新的
AD+ADRD研究人员准备参与旨在改善健康的跨学科合作
通过将新的治疗方法引入临床和采取新的预防措施,
人口。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Kyle M Walsh其他文献
Kyle M Walsh的其他文献
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{{ truncateString('Kyle M Walsh', 18)}}的其他基金
Immune Correlates and Mechanisms of Perinatal Cytomegalovirus Infection and Later Life ALL Development
围产期巨细胞病毒感染和以后生活中 ALL 发展的免疫相关性和机制
- 批准号:
9982817 - 财政年份:2019
- 资助金额:
$ 25.84万 - 项目类别:
Immune Correlates and Mechanisms of Perinatal Cytomegalovirus Infection and Later Life ALL Development
围产期巨细胞病毒感染和以后生活中 ALL 发展的免疫相关性和机制
- 批准号:
9809304 - 财政年份:2019
- 资助金额:
$ 25.84万 - 项目类别:
Genetic Susceptibility to Pediatric Glioma inIndividuals and Diverse populations
个体和不同人群对儿童胶质瘤的遗传易感性
- 批准号:
9742734 - 财政年份:2015
- 资助金额:
$ 25.84万 - 项目类别:
Genetic Susceptibility to Pediatric Glioma inIndividuals and Diverse populations
个体和不同人群对儿童胶质瘤的遗传易感性
- 批准号:
9548184 - 财政年份:2015
- 资助金额:
$ 25.84万 - 项目类别:
Genetic Susceptibility to Pediatric Glioma inIndividuals and Diverse populations
个体和不同人群对儿童胶质瘤的遗传易感性
- 批准号:
9142298 - 财政年份:2015
- 资助金额:
$ 25.84万 - 项目类别:
Genetic Susceptibility to Pediatric Glioma inIndividuals and Diverse populations
个体和不同人群对儿童胶质瘤的遗传易感性
- 批准号:
8864775 - 财政年份:2015
- 资助金额:
$ 25.84万 - 项目类别:
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