Surviving and Thriving in the Real World: A Daily Living Skills Intervention for Adolescents with Autism Spectrum Disorder

在现实世界中生存和发展：自闭症谱系障碍青少年的日常生活技能干预

• 批准号: 10477024
• 负责人: Amie Marie Duncan
• 金额: $ 13.84万
• 依托单位: CINCINNATI CHILDRENS HOSP MED CTR
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-20 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10477024
• 关键词: Activities of Daily Living; Adaptive Behaviors; Adolescent; Adult; Affect; Aftercare; Age; Applications Grants; Area; Assisted Living Facilities; Award; Behavior Therapy; Characteristics; Child; Child Rearing; Chronology; Clinical; Clinical Sciences; Colorado; Communities; Complex; Control Groups; Data; Development; Effectiveness; Employment; Future; Goals; Grant; Group Homes; Home; Hygiene; Impairment; Independent Living; Individual; Intervention; Intervention Trial; K-Series Research Career Programs; Kentucky; Link; Maintenance; Manuscripts; Measures; Medical center; Mentored Patient-Oriented Research Career Development Award; Mentors; Mentorship; Methodology; Modeling; Modification; National Institute of Child Health and Human Development; Obesity; Outcome; Outcome Measure; Parents; Participant; Patient Self-Report; Pediatric Hospitals; Phase; Pilot Projects; Positioning Attribute; Process; Program Evaluation; Psychopathology; Quality of life; Randomized; Randomized Clinical Trials; Reporting; Research; Research Personnel; Secondary Schools; Self Care; Series; Socialization; Statistical Data Interpretation; Technology; Telephone; Testing; Training; Translational Research; Universities; Waiting Lists; Work; Writing; Youth; adolescent with autism spectrum disorder; adult with autism spectrum disorder; associated symptom; autism spectrum disorder; base; behavior observation; clinical center; college; comorbidity; computerized; cooking; coping; design; diaries; effective intervention; efficacy trial; evidence base; executive function; feasibility trial; follow-up; group intervention; improved; individuals with autism spectrum disorder; innovation; intervention program; parental involvement; satisfaction; secondary outcome; skills; social engagement; social skills; surveillance study; treatment group; treatment responders

PROJECT SUMMARY/ABSTRACT Individuals with autism spectrum disorder (ASD), even those defined as high functioning (IQ >70), have significant daily living skills (DLS) deficits that have been linked to poor adult outcome in independent living, post-secondary education, employment, and socializing with others. However, there are currently no intervention packages that target the acquisition of DLS. The resubmission of this Mentored Patient-Oriented Research Career Development Award (K23) supports the candidate's long-term goals of implementing and evaluating effective interventions that target DLS in adolescents with ASD to facilitate a successful transition to adulthood and an increased quality of life. The candidate will pursue her short-term goals by receiving mentorship and training in (1) developing and utilizing rigorous methodology to objectively measure DLS outcomes; (2) conducting randomized clinical trials (RCTs), (3) implementing advanced statistical analyses of RCTs, (4) utilizing goal attainment scaling to measure progress at the individual level, and (5) enhancing manuscript and grant writing skills. The award will be based at Cincinnati Children's Hospital Medical Center under the mentorship of Dr. Lori Stark and co-mentorship of Drs. Avani Modi, Jareen Meinzen-Derr, Judy Reaven (University of Colorado), and Lisa Ruble (University of Kentucky). The proposed research will develop, conduct, and evaluate a feasibility RCT of a group intervention, Surviving and Thriving in the Real World (STRW), to increase DLS (e.g., hygiene, cooking, laundry, and money management) in adolescents with high functioning ASD. An iterative process informed key components of the STRW intervention proposed in the K23 (e.g., specific skills targeted, use of evidence-based strategies, parental involvement, etc.). Prior to conducting the RCT, exploratory DLS outcome measures (i.e., computerized daily phone diaries, behavioral observations of targeted DLS) that directly assess DLS will be developed and piloted. A feasibility RCT of STRW will then be conducted with 56 adolescents with ASD between the ages of 14-21 and their parents. Participants will be randomized to either a STRW or control group (i.e., social skills group). Primary DLS outcomes (i.e., Vineland Adaptive Behavior Scales, 3rd Edition), secondary DLS outcomes (i.e., goal attainment scaling), and exploratory DLS outcomes (i.e., daily phone diaries, direct behavioral observations, self-report of DLS) will be assessed. The preliminary effectiveness of STRW will be compared to the control at post-treatment (Aim 1) and maintenance of treatment gains will be measured at 6-month follow-up (Aim 2). Executive functioning, social skills, psychopathology, and parenting factors will be explored to examine their effect on targeted DLS (Aim 3). A DLS intervention has the potential to directly affect current functioning and future adult outcomes in adolescents with high functioning ASD by increasing capabilities for skills that are needed to be successful in independent living and employment. This research will provide the basis for a more rigorous efficacy trial of the DLS intervention to be proposed in an R01 grant application prior to the end of this K award.

项目总结/文摘

项目成果

Academic Needs in Middle School: Perspectives of Parents and Youth with Autism.

中学的学术需求：自闭症家长和青少年的观点。

• DOI: 10.1007/s10803-019-03995-1
• 发表时间: 2020
• 期刊: Journal of autism and developmental disorders
• 影响因子: 3.9
• 作者: Tamm,Leanne;Duncan,Amie;Vaughn,Aaron;McDade,Rhyanne;Estell,Nicole;Birnschein,Allison;Crosby,Lori
• 通讯作者: Crosby,Lori

School Challenges and Services Related to Executive Functioning for Fully Included Middle Schoolers with Autism.

与全纳自闭症中学生执行功能相关的学校挑战和服务。

• DOI: 10.1177/10883576221110167
• 发表时间: 2023
• 期刊: Focus on autism and other developmental disabilities
• 影响因子: 2
• 作者: Duncan,Amie;Risley,Sydney;Combs,Angela;Lacey,HeatherM;Hamik,Elizabeth;Fershtman,Chaya;Kneeskern,Ellen;Patel,Meera;Crosby,Lori;Hood,AnnaM;Zoromski,AllisonK;Tamm,Leanne
• 通讯作者: Tamm,Leanne

Microanalysis of Daily Living Skills in adolescents with Autism Spectrum Disorder without an intellectual disability.

• DOI: 10.1007/s10803-022-05495-1
• 发表时间: 2023-07
• 期刊: JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
• 影响因子: 3.9
• 作者: Glover, Meredith;Liddle, Melissa;Fassler, Carrie;Duncan, Amie
• 通讯作者: Duncan, Amie

Achieving Independence and Mastery in School: An Open Trial in the Outpatient Setting.

• DOI: 10.1007/s10803-020-04652-8
• 发表时间: 2021-05
• 期刊: Journal of autism and developmental disorders
• 影响因子: 3.9
• 作者: Tamm L;Zoromski AK;Kneeskern EE;Patel M;Lacey HM;Vaughn AJ;Ciesielski HA;Weadick HK;Duncan AW
• 通讯作者: Duncan AW

A Randomized Clinical Trial Targeting Daily Living Skills in Autistic Adolescents Without an Intellectual Disability Before the Transition to Adulthood.

一项针对无智力障碍的自闭症青少年在过渡到成年之前的日常生活技能的随机临床试验。

• DOI: 10.1097/dbp.0000000000001222
• 发表时间: 2023
• 期刊: Journal of developmental and behavioral pediatrics : JDBP
• 作者: Duncan,Amie;Meinzen-Derr,Jareen;Ruble,Lisa;Fassler,Carrie;Stark,LoriJ
• 通讯作者: Stark,LoriJ