Biospecimen Core

生物样本核心

基本信息

项目摘要

BIOSPECIMEN CORE: SUMMARY The Biospecimen Core is a vital resource that supports all brain tumor research at Northwestern, and is especially important in seeing that all projects experience clinical translation within the period of SPORE funding. Regular interactions with the Biostatistics & Bioinformatics Core and Administrative Core will ensure that each project achieves its objectives, and has positive impact on the care of brain tumor patients. The Biospecimen Core will have extensive interactions with all projects and cores by acting as the central repository of patient tissues and renewable tumor resources, by providing the highest quality of tissue analytical services, and by providing neuropathological consultation. The Director of the Core, Dr. Horbinski, as well as the Co-Director, Dr. Daniel Brat, will supervise quality control testing of banked specimens, and will perform all microscopy-based analyses of patient tissues and tumor models for each SPORE project. Biospecimen Core activities will be performed to accomplish the following aims: Aim 1: Provide Northwestern brain tumor researchers with annotated biospecimens from brain tumor patients. Aim 2: Subject all biospecimens to rigorous quality control. Aim 3: Propagate, bank, and characterize surgical specimen derivatives, including PDX and cancer stem cell (CSC) models, to meet ongoing needs for renewable tumor cell sources. Aim 4: Support SPORE projects with biospecimens and neuropathologic analyses.
生物标本芯:总结

项目成果

期刊论文数量(0)
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会议论文数量(0)
专利数量(0)

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Craig Michael Horbinski其他文献

Craig Michael Horbinski的其他文献

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{{ truncateString('Craig Michael Horbinski', 18)}}的其他基金

Targeting IDH mutations to improve seizure control in glioma patients
针对 IDH 突变改善神经胶质瘤患者的癫痫发作控制
  • 批准号:
    10398216
  • 财政年份:
    2020
  • 资助金额:
    $ 24.18万
  • 项目类别:
Targeting IDH mutations to improve seizure control in glioma patients
针对 IDH 突变改善神经胶质瘤患者的癫痫发作控制
  • 批准号:
    10226923
  • 财政年份:
    2020
  • 资助金额:
    $ 24.18万
  • 项目类别:
Interaction between Tissue Factor, Junctional Adhesion Molecule-A, and Integrin B1 to drive self-renewal in glioblastoma
组织因子、连接粘附分子 A 和整合素 B1 之间的相互作用驱动胶质母细胞瘤的自我更新
  • 批准号:
    10331881
  • 财政年份:
    2020
  • 资助金额:
    $ 24.18万
  • 项目类别:
Interaction between Tissue Factor, Junctional Adhesion Molecule-A, and Integrin B1 to drive self-renewal in glioblastoma
组织因子、连接粘附分子 A 和整合素 B1 之间的相互作用驱动胶质母细胞瘤的自我更新
  • 批准号:
    10554404
  • 财政年份:
    2020
  • 资助金额:
    $ 24.18万
  • 项目类别:
Targeting IDH mutations to improve seizure control in glioma patients
针对 IDH 突变改善神经胶质瘤患者的癫痫发作控制
  • 批准号:
    10612395
  • 财政年份:
    2020
  • 资助金额:
    $ 24.18万
  • 项目类别:
Targeting IDH mutations to improve seizure control in glioma patients
针对 IDH 突变改善神经胶质瘤患者的癫痫发作控制
  • 批准号:
    10044076
  • 财政年份:
    2020
  • 资助金额:
    $ 24.18万
  • 项目类别:
Biospecimen Core
生物样本核心
  • 批准号:
    10224122
  • 财政年份:
    2018
  • 资助金额:
    $ 24.18万
  • 项目类别:
Biospecimen Core
生物样本核心
  • 批准号:
    10626397
  • 财政年份:
    2018
  • 资助金额:
    $ 24.18万
  • 项目类别:
Tissue Factor as a Key Determinant of IDH1 Mutant versus IDH1 Wild-type Glioma Thrombosis and Malignancy
组织因子是 IDH1 突变型与 IDH1 野生型胶质瘤血栓形成和恶性肿瘤的关键决定因素
  • 批准号:
    10197235
  • 财政年份:
    2017
  • 资助金额:
    $ 24.18万
  • 项目类别:
Tissue Factor as a Key Determinant of IDH1 Mutant versus IDH1 Wild-type Glioma Thrombosis and Malignancy
组织因子是 IDH1 突变型与 IDH1 野生型胶质瘤血栓形成和恶性肿瘤的关键决定因素
  • 批准号:
    9980502
  • 财政年份:
    2017
  • 资助金额:
    $ 24.18万
  • 项目类别:

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规划方案:CREST生物信息学中心
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Collaborative Research: IIBR: Innovation: Bioinformatics: Linking Chemical and Biological Space: Deep Learning and Experimentation for Property-Controlled Molecule Generation
合作研究:IIBR:创新:生物信息学:连接化学和生物空间:属性控制分子生成的深度学习和实验
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Bioinformatics Core
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    10404414
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