Developmental Research Program

发展研究计划(DRP)：摘要 发育研究计划(DRP)是前列腺孢子的重要组成部分，提供 每年向4-6个经过同行评审并被认为具有潜在翻译潜力的项目提供资金。 资金是灵活的，支持项目的期限为两年或更短时间。预计DRP调查人员 将充分发展和推进其试点项目，以取代没有进展或将 确保前列腺癌研究的独立资金。值得注意的是，更新中提出的所有三个项目 来自试点项目，并提议将调查人员实验室中的发现转化为 诊所。DRP遵循一个高度结构化的过程，向对以下项目感兴趣的调查人员征集项目 开发前列腺癌领域的项目，根据NIH审查标准审查项目，并 监测项目的科学进展。DRP在整个孢子资助期间保持不变。 发展研究方案的具体目标是： ·具体目标1：征集、审查和选择创新和翻译试点项目 结构化流程。向西北大学的调查人员发出申请请求(RFA) (NU)、芝加哥大学及其附属的北岸大学医疗系统。《科学评论》 委员会根据试验项目的质量和对整个孢子任务的重要性进行审查。 ·具体目标2：在孢子总体目标范围内监测试点项目的进展情况。试点项目 调查人员被要求每年两次在孢子调查人员会议上展示他们的结果。他们也 每年与DRP主任举行两次会议，以获得翻译方面的见解，并确保 里程碑正在实现。DRP调查人员必须提交书面进度报告，该报告是 由孢子国际和执行委员会成员进行严格评估。 ·具体目标3：鼓励和招募更多的研究人员通过以下途径开展前列腺癌研究 一个孢子网站，并广泛分发RFA，宣布资金可用。妇女和少数群体 强烈鼓励调查人员提交试点项目。 ·具体目标4：在整个过程中保持发展研究方案的行政程序 孢子资助期。

DEVELOPMENTAL RESEARCH PROGRAM (DRP): ABSTRACT The Developmental Research Program (DRP) is an essential component of the Prostate SPORE, providing yearly funding to 4-6 projects that are peer reviewed and deemed to have promising translational potential. Funding is flexible, supporting projects for a period of two years or less. It is expected that DRP investigators will develop and advance their pilots sufficiently to either replace main projects that are not progressing or will secure independent funding in prostate cancer research. Of note, all three projects presented in the renewal have emanated from pilot projects and propose translating discoveries made in the investigators’ labs to the clinic. The DRP follows a highly structured process to solicit projects from investigators who are interested in developing projects in the area of prostate cancer, to review projects according to NIH review criteria and to monitor projects for scientific progress. The DRP is maintained throughout the entire period of SPORE funding. The specific aims of the Developmental Research Program are: • Specific Aim 1: To solicit, review and select innovative and translational pilot projects through the highly structured process. A request for applications (RFA) is sent out to investigators at the Northwestern University (NU), University of Chicago and its affiliated NorthShore University HealthSystems. The Scientific Review Committee reviews pilot projects based on the quality and importance to the overall SPORE mission. • Specific Aim 2: To monitor progress of pilot projects within the context of the overall SPORE goals. Pilot project investigators are required to present their results twice per year at SPORE investigators meeting. They also meet twice per year with the Directors of the DRP to obtain translational insight and to ensure that scientific milestones are being achieved. DRP investigators are required to submit a written progress report that is rigorously evaluated by the SPORE PI and members of the Executive Committee. • Specific Aim 3: To encourage and recruit additional investigators to pursue research in prostate cancer through a SPORE web site and by widely distributing the RFA announcing the availability of funds. Women and minority investigators are strongly encouraged to submit pilot projects. • Specific Aim 4: To maintain the administrative process for the Developmental Research Program throughout the SPORE funding period.