Developmental Research Program

药物研究计划（DRP）：摘要 发展研究计划（DRP）是前列腺孢子的重要组成部分，提供 每年资助4-6个经过同行评审并被认为具有翻译潜力的项目。 资金是灵活的，支持项目为期两年或更短。 将充分发展和推进其试点项目，以取代没有进展的主要项目，或将 确保前列腺癌研究的独立资金。值得注意的是，所有三个项目提出的更新 来自试点项目，并建议将研究人员实验室中的发现转化为 诊所DRP遵循一个高度结构化的流程，从感兴趣的研究人员那里征集项目， 制定前列腺癌领域的项目，根据NIH审查标准审查项目， 监测项目以促进科学进步。DRP在整个SPORE供资期间保持不变。 发展研究方案的具体目标是： ·具体目标1：通过高度重视的国际合作，征求、审查和选择创新和转化试点项目。 结构化过程。申请请求（RFA）被发送给西北大学的研究人员 (NU)，芝加哥大学及其附属的北岸大学健康系统。科学审查 委员会根据质量和对整个SPORE使命的重要性审查试点项目。 ·具体目标2：在整个SPORE目标范围内监测试点项目的进展情况。试点项目 要求研究者每年在SPORE研究者会议上提交两次研究结果。他们还 每年与DRP主任会面两次，以获得翻译见解，并确保科学 正在实现里程碑。DRP研究者需要提交书面进度报告， 由SPORE PI和执行委员会成员严格评估。 ·具体目标3：鼓励和招募更多的研究人员进行前列腺癌的研究， 一个SPORE网站，并广泛分发RFA，宣布资金的可用性。妇女和少数 大力鼓励调查人员提交试点项目。 ·具体目标4：在整个过程中维持发展研究计划的行政程序 融资周期。

DEVELOPMENTAL RESEARCH PROGRAM (DRP): ABSTRACT The Developmental Research Program (DRP) is an essential component of the Prostate SPORE, providing yearly funding to 4-6 projects that are peer reviewed and deemed to have promising translational potential. Funding is flexible, supporting projects for a period of two years or less. It is expected that DRP investigators will develop and advance their pilots sufficiently to either replace main projects that are not progressing or will secure independent funding in prostate cancer research. Of note, all three projects presented in the renewal have emanated from pilot projects and propose translating discoveries made in the investigators’ labs to the clinic. The DRP follows a highly structured process to solicit projects from investigators who are interested in developing projects in the area of prostate cancer, to review projects according to NIH review criteria and to monitor projects for scientific progress. The DRP is maintained throughout the entire period of SPORE funding. The specific aims of the Developmental Research Program are: • Specific Aim 1: To solicit, review and select innovative and translational pilot projects through the highly structured process. A request for applications (RFA) is sent out to investigators at the Northwestern University (NU), University of Chicago and its affiliated NorthShore University HealthSystems. The Scientific Review Committee reviews pilot projects based on the quality and importance to the overall SPORE mission. • Specific Aim 2: To monitor progress of pilot projects within the context of the overall SPORE goals. Pilot project investigators are required to present their results twice per year at SPORE investigators meeting. They also meet twice per year with the Directors of the DRP to obtain translational insight and to ensure that scientific milestones are being achieved. DRP investigators are required to submit a written progress report that is rigorously evaluated by the SPORE PI and members of the Executive Committee. • Specific Aim 3: To encourage and recruit additional investigators to pursue research in prostate cancer through a SPORE web site and by widely distributing the RFA announcing the availability of funds. Women and minority investigators are strongly encouraged to submit pilot projects. • Specific Aim 4: To maintain the administrative process for the Developmental Research Program throughout the SPORE funding period.