Chicago CCFC for the new AsA-NHPI cohort

芝加哥 CCFC 新 AsA-NHPI 队列

• 批准号: 10724064
• 负责人: Briseis A Aschebrook-Kilfoy
• 金额: $ 59.57万
• 依托单位: UNIVERSITY OF CHICAGO
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-08-15 至 2025-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10724064
• 关键词: Address; Adopted; Adult; Advocacy; Agreement; All of Us Research Program; Ancillary Study; Area; Asian; Asian Americans; Asian population; Behavioral; Cambodian; Censuses; Chicago; Clinic; Clinical; Clinical Protocols; Cohort Studies; Collaborations; Communities; Complement; Consent; Data; Data Collection; Development; Disease; Disparity; Documentation; Enrollment; Ensure; Epidemiology; Equilibrium; Filipino; Focus Groups; Funding; Funding Opportunities; Genetic; Genetic Research; Geography; Goals; Grant; Health; Health Promotion; Home; Human Resources; Institution; Intervention; Investigation; Knowledge; Koreans; Lead; Leadership; Logistics; Medical; Methods; Minority Health Research; Modeling; Molecular; Neighborhoods; Organizational Objectives; Participant; Performance; Phase; Pilot Projects; Precision Health; Prevention; Process; Protocols documentation; Questionnaires; Randomized; Readiness; Research; Research Infrastructure; Research Methodology; Research Personnel; Resources; Sampling; Science; Site; South Asian; Subgroup; Surveys; Training; Underrepresented Minority; United States National Institutes of Health; Universities; Vietnamese; Work; bilingualism; biobank; cohort; collaborative approach; community based participatory research; community engagement; community partnership; community setting; cost; cultural competence; design; diverse data; ethnic diversity; experience; follow-up; health disparity; health equity; improved; innovation; metropolitan; multidisciplinary; outreach; pilot test; population based; population health; racial diversity; recruit; research study; response; social; southeast Asian; success

PROJECT SUMMARY/ABSTRACT The University of Chicago (UChicago) Center for Asian Health Equity (CAHE) and the Institute for Population and Precision Health (IPPH) put forth this plan to leverage decades of experience enrolling underrepresented minorities, and especially Asian Americans, into health studies and epidemiologic cohorts as a clinic/community field site for the new NIH-funded AsA-NHPI Cohort (NAC). We plan to enroll 2,500 participants from communities in the metropolitan Chicago area with large Asian subgroup representation using a population-based sampling framework. We will specifically target South Asian, Korean, Filipino and Southeast Asians (Cambodian, Vietnamese, and Laotian) in randomized census tracts using a 2-stage sampling design. Our long-term partner, the Asian Health Coalition (AHC) has been serving as the national engagement lead for the All of Us Research Program and has set the national model for community engaged cohorts tailored to Asian inclusion. We have identified active community partners who are already supporting enrollment into a similar protocol. In this proposal, the UChicago MPIs and team enthusiastically propose a collaborative approach to meet the RFA milestones; building on prior success and experience working on national multisite cohorts with an emphasis on racial diversity, scientific rigor, and innovative approaches to improve health disparities. We suggest an approach and methods for consideration for the common protocol during the UG3 period, with full appreciation for the balance of decisions that will need to be made to ensure efficient recruitment, comprehensive yet not burdensome surveys, thoughtful clinical protocols that can be implemented in a community or in-home setting, and high-quality biospecimens processed and banked to support scientific investigation and ancillary studies. We plan to hire bilingual, bicultural individuals from the Asian community and train them to work as “community ambassadors (CAs)” during the entire study period, a model that has proven highly effective in Asian communities previously, promoting both participation and retention. We have an institutional commitment to deploy mobile medical units (MMUs) and study vans to targeted study areas at no cost to the grant to ensure that we can lower barriers to participation. We are confident that our proposed approach will allow us to meet the cohort UG3 and UH3 milestones, short-, mid- and long-term goals, and contribute significantly to this important effort in all phases.

项目摘要/摘要 芝加哥大学（U芝加哥）亚洲健康公平中心（CAHE）和人口研究所 和精准健康（IPPH）提出了这一计划，以利用数十年的经验，招募代表性不足 少数民族，特别是亚裔美国人，进入健康研究和流行病学队列， 新的NIH资助的AsA-NHPI队列（NAC）的诊所/社区现场。我们计划招收2500人 来自大都会芝加哥地区社区的参与者，其中有大量亚洲亚组代表 使用基于人口的抽样框架。我们将专门针对南亚、韩国、菲律宾和 使用2阶段随机人口普查区域中的东南亚人（柬埔寨人、越南人和老挝人） 抽样设计我们的长期合作伙伴，亚洲健康联盟（AHC）一直担任国家 参与领导我们所有的研究计划，并建立了国家模式，社区参与 专为亚洲人群设计的队列。我们已经确定了积极的社区合作伙伴， 入组类似方案。在这个提案中，芝加哥大学的MPI和团队热情地提出了一个 采用协作方式实现RFA里程碑;在先前的成功和经验的基础上， 国家多地点队列，强调种族多样性，科学严谨性和创新方法， 改善健康差距。我们提出了一个共同议定书的审议办法和方法 在UG 3期间，充分认识到需要作出的决定的平衡，以确保 有效的招募，全面但不繁琐的调查，周到的临床协议，可以 在社区或家庭环境中实施，并处理和储存高质量的生物标本， 支持科学调查和辅助研究。我们计划聘请双语，双文化的个人从 亚洲社区，并培训他们在整个学习期间担任“社区大使（CA）”， 这种模式以前在亚洲社区被证明非常有效，既促进了参与， 潴留我们有一个机构的承诺，部署移动的医疗单位（MMU）和研究车， 有针对性的研究领域，在没有费用的赠款，以确保我们可以降低参与的障碍。我们 相信我们提出的方法将使我们能够满足UG 3和UH 3队列的里程碑，短期，中期， 和长期目标，并在所有阶段为这一重要努力作出重大贡献。