Research Training for Physician-Scientists in Gastrointestinal Oncology

胃肠肿瘤学医师科学家研究培训

基本信息

  • 批准号:
    10478062
  • 负责人:
  • 金额:
    $ 27.91万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2015
  • 资助国家:
    美国
  • 起止时间:
    2015-07-01 至 2025-07-31
  • 项目状态:
    未结题

项目摘要

Summary This is the first application for renewal of T32 CA193111 to continue funding the training of next generation of physician-scientists in gastrointestinal oncology. We believe that physician-scientists armed with rigorous research training are necessary to discover and translate new advances in GI oncology as well as to investigate critical issues facing delivery of cancer care to patients. Our trainees are drawn from NYU’s renowned clinical fellowship programs in Medical Oncology or Gastroenterology or top-notch residency programs in Radiation Oncology or Surgery. Trainees take a 2-3 year hiatus from clinical activities to engage in intensive full-time training in GI cancer research. Our program is composed of (i) a Basic/Translational Science track aimed at individuals who wish to direct their own basic science laboratory in GI oncology or individuals who want to lead translational research programs that comfortably interface between the pre-clinical laboratory and clinical investigation and (ii) a Population Sciences tract for trainees who seek careers in the diverse fields of population sciences including cancer epidemiology, comparative effectiveness, disparities, health services, or outcomes research. The program for our Basic/Translational Science track consists of two years of individualized mentored research in faculty laboratories, enhanced by a strong parallel didactic program in cancer biology. The Population Sciences track is centered on a rigorous Masters-level curriculum that teaches clinical trial design, epidemiology, comparative-effectiveness, and outcomes research methodologies along with a mentored research project based in population sciences. The two tracks are united through a weekly 2-hour core curriculum covering essential topics in GI cancer and critical lessons for cancer physicians embarking on independent investigative careers. We plan to continue to have a steady-state of 4 trainees at any given time. Our first group of graduates have been very successful in acquiring the research skills and credentials to eventually lead their own research groups. We are proud that our first graduates have obtained academic positions in oncology and submitted highly scored K grants. Our trainees are nurtured by a cadre of mentors with substantial accomplishments in cancer research and stellar training records. The aim of our training program is to continue to graduate physician- scientists armed with the intellectual capacity and tools to lead their own research programs and become leaders and role models in investigative GI oncology.
摘要 这是T32 CA193111首次申请续签,以继续资助下一代 内科医生-胃肠道肿瘤学的科学家。我们相信,内科科学家配备了严格的 研究培训是必要的,以发现和转化胃肠道肿瘤学的新进展以及调查 向患者提供癌症护理所面临的关键问题。我们的实习生来自纽约大学著名的临床 医学肿瘤学或胃肠病学奖学金项目或放射领域的顶尖住院医师项目 肿瘤学或外科。实习生从临床活动中抽出2-3年的时间从事高强度的全职工作 在胃肠道癌症研究方面的培训。我们的计划由(I)基础/翻译科学轨道组成,旨在 希望指导自己的胃肠道肿瘤学基础科学实验室的个人或希望领导 在临床前实验室和临床之间轻松对接的转化性研究计划 调查和(2)为在不同人口领域寻求职业的受训人员编写的人口科学手册 包括癌症流行病学、比较有效性、差异、卫生服务或结果在内的科学 研究。我们的基础/翻译科学课程包括两年的个性化指导 学院实验室的研究,由癌症生物学的强有力的平行教学计划加强。人口 Science Track以严格的硕士课程为中心,教授临床试验设计、流行病学、 比较有效性和结果研究方法,以及有指导的研究项目 以人口科学为基础。这两个课程通过每周2小时的核心课程统一起来,内容包括 胃肠道癌症的基本主题和癌症医生开始独立研究的重要教训 事业。我们计划继续在任何给定的时间拥有4名学员的稳定状态。我们的第一批毕业生 已经非常成功地获得了研究技能和资质,最终领导自己的研究 组。我们感到自豪的是,我们的第一批毕业生已经获得了肿瘤学的学术职位,并提交了很高的 获得了K级拨款。我们的学员是由一批在癌症方面取得重大成就的导师培养出来的。 研究和一流的训练记录。我们的培训计划的目标是继续毕业于医生- 科学家拥有领导自己的研究计划并成为领导者的智力能力和工具 和研究胃肠道肿瘤学的榜样。

项目成果

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{{ truncateString('DAFNA BAR-SAGI', 18)}}的其他基金

A novel monobody-drug conjugate to treat mutant KRas pancreatic cancer.
一种治疗突变型 KRas 胰腺癌的新型单体药物缀合物。
  • 批准号:
    10666997
  • 财政年份:
    2022
  • 资助金额:
    $ 27.91万
  • 项目类别:
A novel monobody-drug conjugate to treat mutant KRas pancreatic cancer.
一种治疗突变型 KRas 胰腺癌的新型单体药物缀合物。
  • 批准号:
    10323748
  • 财政年份:
    2021
  • 资助金额:
    $ 27.91万
  • 项目类别:
A novel monobody-drug conjugate to treat mutant Ras multiple myeloma
一种治疗突变 Ras 多发性骨髓瘤的新型单体药物偶联物
  • 批准号:
    10080987
  • 财政年份:
    2020
  • 资助金额:
    $ 27.91万
  • 项目类别:
Dectin-1 signaling drives pancreatic oncogenesis by inducing macrophage-mediated adaptive immune suppression
Dectin-1 信号传导通过诱导巨噬细胞介导的适应性免疫抑制来驱动胰腺肿瘤发生
  • 批准号:
    10359672
  • 财政年份:
    2017
  • 资助金额:
    $ 27.91万
  • 项目类别:
Dectin-1 signaling drives pancreatic oncogenesis by inducing macrophage-mediated adaptive immune suppression
Dectin-1 信号传导通过诱导巨噬细胞介导的适应性免疫抑制来驱动胰腺肿瘤发生
  • 批准号:
    10054171
  • 财政年份:
    2017
  • 资助金额:
    $ 27.91万
  • 项目类别:
Oncogenic Ras-induced macropinocytosis: A new paradigm for metabolic adaptation
致癌 Ras 诱导的巨胞饮作用:代谢适应的新范例
  • 批准号:
    10208796
  • 财政年份:
    2016
  • 资助金额:
    $ 27.91万
  • 项目类别:
Oncogenic Ras-induced macropinocytosis: A new paradigm for metabolic adaptation
致癌 Ras 诱导的巨胞饮作用:代谢适应的新范例
  • 批准号:
    9348606
  • 财政年份:
    2016
  • 资助金额:
    $ 27.91万
  • 项目类别:
Oncogenic Ras-induced macropinocytosis: A new paradigm for metabolic adaptation
致癌 Ras 诱导的巨胞饮作用:代谢适应的新范例
  • 批准号:
    9979778
  • 财政年份:
    2016
  • 资助金额:
    $ 27.91万
  • 项目类别:
Oncogenic Ras-induced macropinocytosis: A new paradigm for metabolic adaptation
致癌 Ras 诱导的巨胞饮作用:代谢适应的新范例
  • 批准号:
    10430204
  • 财政年份:
    2016
  • 资助金额:
    $ 27.91万
  • 项目类别:
Oncogenic Ras-induced macropinocytosis: A new paradigm for metabolic adaptation
致癌 Ras 诱导的巨胞饮作用:代谢适应的新范例
  • 批准号:
    9190721
  • 财政年份:
    2016
  • 资助金额:
    $ 27.91万
  • 项目类别:

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