Research Training for Physician-Scientists in Gastrointestinal Oncology

胃肠肿瘤学医师科学家研究培训

基本信息

  • 批准号:
    10478062
  • 负责人:
  • 金额:
    $ 27.91万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2015
  • 资助国家:
    美国
  • 起止时间:
    2015-07-01 至 2025-07-31
  • 项目状态:
    未结题

项目摘要

Summary This is the first application for renewal of T32 CA193111 to continue funding the training of next generation of physician-scientists in gastrointestinal oncology. We believe that physician-scientists armed with rigorous research training are necessary to discover and translate new advances in GI oncology as well as to investigate critical issues facing delivery of cancer care to patients. Our trainees are drawn from NYU’s renowned clinical fellowship programs in Medical Oncology or Gastroenterology or top-notch residency programs in Radiation Oncology or Surgery. Trainees take a 2-3 year hiatus from clinical activities to engage in intensive full-time training in GI cancer research. Our program is composed of (i) a Basic/Translational Science track aimed at individuals who wish to direct their own basic science laboratory in GI oncology or individuals who want to lead translational research programs that comfortably interface between the pre-clinical laboratory and clinical investigation and (ii) a Population Sciences tract for trainees who seek careers in the diverse fields of population sciences including cancer epidemiology, comparative effectiveness, disparities, health services, or outcomes research. The program for our Basic/Translational Science track consists of two years of individualized mentored research in faculty laboratories, enhanced by a strong parallel didactic program in cancer biology. The Population Sciences track is centered on a rigorous Masters-level curriculum that teaches clinical trial design, epidemiology, comparative-effectiveness, and outcomes research methodologies along with a mentored research project based in population sciences. The two tracks are united through a weekly 2-hour core curriculum covering essential topics in GI cancer and critical lessons for cancer physicians embarking on independent investigative careers. We plan to continue to have a steady-state of 4 trainees at any given time. Our first group of graduates have been very successful in acquiring the research skills and credentials to eventually lead their own research groups. We are proud that our first graduates have obtained academic positions in oncology and submitted highly scored K grants. Our trainees are nurtured by a cadre of mentors with substantial accomplishments in cancer research and stellar training records. The aim of our training program is to continue to graduate physician- scientists armed with the intellectual capacity and tools to lead their own research programs and become leaders and role models in investigative GI oncology.
概括 这是T32 CA193111的首个续签申请,以继续资助下一代的培训 胃肠道肿瘤学的医师科学家。我们相信,拥有严格的医学科学家 研究培训对于发现和转化胃肠道肿瘤学的新进展以及调查是必要的 向患者提供癌症护理面临的关键问题。我们的学员来自纽约大学著名的临床 肿瘤内科或胃肠病学研究金计划或放射科一流住院医师计划 肿瘤学或外科。学员会中断临床活动 2-3 年,从事强化全职工作 胃肠道癌症研究培训。我们的计划由 (i) 基础/转化科学轨道组成,旨在 希望领导自己的胃肠道肿瘤学基础科学实验室的个人或想要领导的个人 临床前实验室和临床之间顺利衔接的转化研究项目 调查和 (ii) 为在人口不同领域寻求职业的学员提供的人口科学手册 科学,包括癌症流行病学、比较有效性、差异、卫生服务或结果 研究。我们的基础/转化科学课程包括两年的个性化指导 学院实验室的研究,通过癌症生物学方面强大的并行教学计划得到加强。人口 科学课程以严格的硕士水平课程为中心,教授临床试验设计、流行病学、 比较有效性和结果研究方法以及指导研究项目 以人口科学为基础。这两个方向通过每周 2 小时的核心课程结合在一起,涵盖 胃肠道癌症的基本主题以及癌症医生开展独立研究的重要教训 职业生涯。我们计划在任何特定时间继续保持 4 名学员的稳定状态。我们的第一批毕业生 非常成功地获得了研究技能和证书,最终领导了自己的研究 组。我们感到自豪的是,我们的第一批毕业生获得了肿瘤学领域的学术职位,并提交了高度评价 获得 K 补助金。我们的学员由一批在癌症领域取得重大成就的导师培养 研究和出色的培训记录。我们培训计划的目的是继续毕业医师 拥有智力能力和工具的科学家可以领导自己的研究项目并成为领导者 和研究胃肠道肿瘤学的榜样。

项目成果

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{{ truncateString('DAFNA BAR-SAGI', 18)}}的其他基金

A novel monobody-drug conjugate to treat mutant KRas pancreatic cancer.
一种治疗突变型 KRas 胰腺癌的新型单体药物缀合物。
  • 批准号:
    10666997
  • 财政年份:
    2022
  • 资助金额:
    $ 27.91万
  • 项目类别:
A novel monobody-drug conjugate to treat mutant KRas pancreatic cancer.
一种治疗突变型 KRas 胰腺癌的新型单体药物缀合物。
  • 批准号:
    10323748
  • 财政年份:
    2021
  • 资助金额:
    $ 27.91万
  • 项目类别:
A novel monobody-drug conjugate to treat mutant Ras multiple myeloma
一种治疗突变 Ras 多发性骨髓瘤的新型单体药物偶联物
  • 批准号:
    10080987
  • 财政年份:
    2020
  • 资助金额:
    $ 27.91万
  • 项目类别:
Dectin-1 signaling drives pancreatic oncogenesis by inducing macrophage-mediated adaptive immune suppression
Dectin-1 信号传导通过诱导巨噬细胞介导的适应性免疫抑制来驱动胰腺肿瘤发生
  • 批准号:
    10359672
  • 财政年份:
    2017
  • 资助金额:
    $ 27.91万
  • 项目类别:
Dectin-1 signaling drives pancreatic oncogenesis by inducing macrophage-mediated adaptive immune suppression
Dectin-1 信号传导通过诱导巨噬细胞介导的适应性免疫抑制来驱动胰腺肿瘤发生
  • 批准号:
    10054171
  • 财政年份:
    2017
  • 资助金额:
    $ 27.91万
  • 项目类别:
Oncogenic Ras-induced macropinocytosis: A new paradigm for metabolic adaptation
致癌 Ras 诱导的巨胞饮作用:代谢适应的新范例
  • 批准号:
    10208796
  • 财政年份:
    2016
  • 资助金额:
    $ 27.91万
  • 项目类别:
Oncogenic Ras-induced macropinocytosis: A new paradigm for metabolic adaptation
致癌 Ras 诱导的巨胞饮作用:代谢适应的新范例
  • 批准号:
    9348606
  • 财政年份:
    2016
  • 资助金额:
    $ 27.91万
  • 项目类别:
Oncogenic Ras-induced macropinocytosis: A new paradigm for metabolic adaptation
致癌 Ras 诱导的巨胞饮作用:代谢适应的新范例
  • 批准号:
    9979778
  • 财政年份:
    2016
  • 资助金额:
    $ 27.91万
  • 项目类别:
Oncogenic Ras-induced macropinocytosis: A new paradigm for metabolic adaptation
致癌 Ras 诱导的巨胞饮作用:代谢适应的新范例
  • 批准号:
    10430204
  • 财政年份:
    2016
  • 资助金额:
    $ 27.91万
  • 项目类别:
Oncogenic Ras-induced macropinocytosis: A new paradigm for metabolic adaptation
致癌 Ras 诱导的巨胞饮作用:代谢适应的新范例
  • 批准号:
    9190721
  • 财政年份:
    2016
  • 资助金额:
    $ 27.91万
  • 项目类别:

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