Advancing womenâÂÂs health through research: the UNC WRHR Career Development Program

项目摘要 妇产科医生在妇女生殖健康研究中发挥着不可或缺的作用。然而，Ob- 妇科调查人员历来在该领域的代表性不足，导致关键的机会， 产生临床相关的研究问题，并将新的发现转化为临床实践。解决 这一重要差距，我们建议重新建立妇女生殖健康研究职业发展 在查佩尔山的北卡罗来纳州大学的项目。我们的目标是促进早期职业发展， 有前途的Ob-Gyn临床研究人员，并支持合作，尖端研究，推进 妇女生殖健康领域。该计划提供指导，结构化的职业发展 活动，并至少75%的保护研究时间为两个Ob-Gyn学者每年。基于先前的WRHR 成功（2005 - 2010年），我们设计了一个程序，解决了早期职业妇产科的需求 研究人员首先，我们的学者嵌入在我们的Ob部门内充满活力的研究环境中， Gyn，每年由NIH，其他联邦机构和 层.我们的学者将在申请中指定的重点领域内进行指导研究， 与女性生殖健康的交集其中包括由以下机构领导的已建立的研究领域： 项目教师和多个NIH奖项的支持（妊娠并发症，情绪障碍和 药物使用、肥胖和心脏代谢疾病、性健康和生殖健康）。工作机会 还将提供由个人供资的调查员负责的新兴领域。第二，我们的学者将得到指导， 经验丰富的教师。导师委员会由NIH资助的Ob-Gyn研究人员领导，并由 合作的教师从医学院，公共卫生，药学，护理和社会工作。 第三，我们已经开发了一个强大的职业发展课程，利用现有的K12/KL2资源 但其目标和宗旨却截然不同。更广泛的早期职业，研究- 面向教师提供网络，共享学习和点对点指导的机会， 最大限度地减少学术孤立的风险。第四，我们的项目得到了北卡罗来纳大学的卓越机构支持 医学院。这包括一个重大的成本分担的承诺，以确保有竞争力的初级教师 工资，在部门的专业和亚专业教师相称。学者们也将获得 通过大学范围内的中心和研究所获得额外的机构资源。的首要目标 EARWRHR计划是为了支持有前途的早期职业妇产科医生在往往脆弱的过渡， 研究独立性。通过获得一个无与伦比的经验丰富的教师导师和 凭借其职业发展课程的优势，我们的计划将开发下一代独立的NIH 妇女生殖健康调查员。

PROJECT SUMMARY Obstetrician-gynecologists have an integral role to play in women’s reproductive health research. However, Ob- Gyn investigators have historically been underrepresented in the field, leading to critical missed opportunities to generate clinically-relevant research questions and to translate new findings into clinical practice. To address this important gap, we propose to re-establish the Women’s Reproductive Health Research Career Development Program at the University of North Carolina at Chapel Hill. Our aims are to catalyze early career development of promising Ob-Gyn clinician investigators and to support collaborative, cutting edge research that advances the field of women’s reproductive health. This program provides mentorship, structured career development activities, and at least 75% protected research time for two Ob-Gyn scholars annually. Building upon prior WRHR success (2005-2010), we have designed a program that addresses the needs of early career Ob-Gyn researchers. First, our scholars are embedded in a vibrant research environment within our Department of Ob- Gyn, which is supported by $14 million in annual research funding from NIH, other federal agencies, and foundations. Our scholars will conduct mentored research within emphasis areas designated in the application, at their intersection with women’s reproductive health. These include established research domains led by program faculty and supported by multiple NIH awards (complications of pregnancy, mood disorders and substance use, obesity and cardiometabolic disease, sexual and reproductive health). Opportunities to work in emerging areas with individual, funded investigators will also be offered. Second, our scholars will be mentored by experienced faculty. Mentorship committees are led by NIH-funded Ob-Gyn investigators and supported by collaborating faculty from the UNC Schools of Medicine, Public Health, Pharmacy, Nursing, and Social Work. Third, we have developed a robust career development curriculum that leverages existing K12/KL2 resources at UNC, while remaining distinct in its goals and purpose. This broader community of early career, research- oriented faculty provides opportunities for networking, shared learning, and peer-to-peer mentorship, and minimizes the risk of academic isolation. Fourth, our program has exceptional institutional support from the UNC School of Medicine. This includes a commitment of significant cost-sharing to ensure competitive junior faculty salaries, commensurate with specialty and subspecialty faculty in the department. Scholars will also have access to additional institutional resources through university-wide centers and institutes. The overarching goal of the UNC WRHR Program is to support promising early career Ob-Gyns during the often tenuous transition to research independence. Through access to an unparalleled group of experienced faculty mentors and the strength of its career development curriculum, our program will develop the next generation of independent NIH investigators in women’s reproductive health.