Advancing womenâÂÂs health through research: the UNC WRHR Career Development Program

通过研究促进女性健康：北卡罗来纳大学 WRHR 职业发展计划

• 批准号: 10677529
• 负责人: Genevieve S. Neal-Perry
• 金额: $ 16.27万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-07-23 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10677529
• 关键词: Address; Area; Award; Cardiometabolic Disease; Collaborations; Communities; Cost Sharing; Discipline of Nursing; Ensure; Environment; Faculty; Foundations; Funding; Goals; Gynecologist; Health; Individual; Institution; Learning; Mentored Clinical Scientist Development Program; Mentors; Mentorship; Mood Disorders; North Carolina; Obesity; Pharmacy facility; Play; Pregnancy Complications; Program Development; Public Health; Reproductive Health; Research; Research Personnel; Resources; Role; Sexual Health; Social Work; Structure; Time; Translating; United States National Institutes of Health; Universities; Wages; Woman; Work; career; career development; clinical practice; clinically relevant; curriculum development; design; experience; faculty mentor; medical schools; medical specialties; next generation; peer; programs; risk minimization; substance use; success

PROJECT SUMMARY Obstetrician-gynecologists have an integral role to play in women’s reproductive health research. However, Ob- Gyn investigators have historically been underrepresented in the field, leading to critical missed opportunities to generate clinically-relevant research questions and to translate new findings into clinical practice. To address this important gap, we propose to re-establish the Women’s Reproductive Health Research Career Development Program at the University of North Carolina at Chapel Hill. Our aims are to catalyze early career development of promising Ob-Gyn clinician investigators and to support collaborative, cutting edge research that advances the field of women’s reproductive health. This program provides mentorship, structured career development activities, and at least 75% protected research time for two Ob-Gyn scholars annually. Building upon prior WRHR success (2005-2010), we have designed a program that addresses the needs of early career Ob-Gyn researchers. First, our scholars are embedded in a vibrant research environment within our Department of Ob- Gyn, which is supported by $14 million in annual research funding from NIH, other federal agencies, and foundations. Our scholars will conduct mentored research within emphasis areas designated in the application, at their intersection with women’s reproductive health. These include established research domains led by program faculty and supported by multiple NIH awards (complications of pregnancy, mood disorders and substance use, obesity and cardiometabolic disease, sexual and reproductive health). Opportunities to work in emerging areas with individual, funded investigators will also be offered. Second, our scholars will be mentored by experienced faculty. Mentorship committees are led by NIH-funded Ob-Gyn investigators and supported by collaborating faculty from the UNC Schools of Medicine, Public Health, Pharmacy, Nursing, and Social Work. Third, we have developed a robust career development curriculum that leverages existing K12/KL2 resources at UNC, while remaining distinct in its goals and purpose. This broader community of early career, research- oriented faculty provides opportunities for networking, shared learning, and peer-to-peer mentorship, and minimizes the risk of academic isolation. Fourth, our program has exceptional institutional support from the UNC School of Medicine. This includes a commitment of significant cost-sharing to ensure competitive junior faculty salaries, commensurate with specialty and subspecialty faculty in the department. Scholars will also have access to additional institutional resources through university-wide centers and institutes. The overarching goal of the UNC WRHR Program is to support promising early career Ob-Gyns during the often tenuous transition to research independence. Through access to an unparalleled group of experienced faculty mentors and the strength of its career development curriculum, our program will develop the next generation of independent NIH investigators in women’s reproductive health.

项目摘要 妇产科医生在妇女的生殖健康研究中起着不可或缺的作用。但是，ob- GYN调查人员历来在该领域的人数不足，导致了严重的错过机会 产生与临床相关的研究问题，并将新发现转化为临床实践。解决 这一重要差距，我们建议重新建立妇女的生殖健康研究职业发展 在北卡罗来纳大学教堂山的计划。我们的目的是促进早期职业发展 有希望的OB-GYN临床研究人员并支持合作，尖端的研究进步 妇女生殖健康领域。该计划提供了精通，结构化的职业发展 每年两名OB-GYN学者的活动至少有75％的研究时间。在先前的WRHR之后 成功（2005-2010），我们设计了一个计划，以满足早期职业生涯的需求 研究人员。首先，我们的学者被嵌入到我们的Ob-部门的充满活力的研究环境中 Gyn，由NIH，其他联邦机构和 基础。我们的学者将在应用程序指定的重点领域内进行指导的研究， 在与女性生殖健康的交汇处。这些包括由 计划教师，并获得多个NIH奖项（怀孕的并发症，情绪障碍和 药物使用，肥胖和心脏代谢疾病，性和生殖健康）。工作机会 还将提供带有个人资助的调查人员的新兴地区。其次，我们的学者将被考虑 由经验丰富的教师。指导委员会由NIH资助的OB-GYN调查人员领导，并由 与UNC医学，公共卫生，药房，护理和社会工作的UNC学校合作。 第三，我们开发了一个强大的职业发展课程，利用现有的K12/KL2资源 在UNC上，同时在其目标和目的方面保持截然不同。这个更广泛的早期职业社区，研究 - 面向的教师为网络，共享学习和点对点心态提供机会，以及 最小化学术隔离的风险。第四，我们的计划获得了UNC的特殊机构支持 医学院。这包括大量成本分担的承诺，以确保有竞争力的初级教师 工资与该系的专业和专业教师相称。学者也将可以访问 通过大学范围内的中心和机构提供其他机构资源。总体目标 UNC WRHR计划是在经常微弱的过渡中支持承诺早期职业生涯 研究独立性。通过进入无与伦比的一群经验丰富的教师导师和 我们的职业发展课程的优势，我们的计划将发展下一代独立NIH 妇女复制健康的调查人员。

项目成果

Endocarditis, drug use and biological sex: A statewide analysis comparing sex differences in drug use-associated infective endocarditis with other drug-related harms.

心内膜炎、吸毒和生物性别：一项全州范围内的分析，比较了吸毒相关感染性心内膜炎与其他吸毒相关危害的性别差异。

• DOI: 10.1016/j.drugpo.2023.104280
• 发表时间: 2024
• 期刊: The International journal on drug policy
• 作者: McCrary,LMadeline;Cox,MaryE;Roberts,KateE;Knittel,AndreaK;Jordan,RobynA;Proescholdbell,ScottK;Schranz,AsherJ
• 通讯作者: Schranz,AsherJ

Ethical inclusion: Risks and benefits of research from the perspective of perinatal people with opioid use disorders who have experienced incarceration.

• DOI: 10.1371/journal.pone.0294604
• 发表时间: 2023
• 期刊: PLOS ONE
• 影响因子: 3.7
• 作者: Reddy, Julia;Black, Kristel;Bazemore, Keia;Jordan, Kiva;Jackson, Jamie B.;Knittel, Andrea K.
• 通讯作者: Knittel, Andrea K.

Experiences of menopause during incarceration.

• DOI: 10.1097/gme.0000000000001762
• 发表时间: 2021-03-11
• 期刊: Menopause (New York, N.Y.)
• 作者: Jaffe EF;Palmquist AEL;Knittel AK
• 通讯作者: Knittel AK

Standardized outcome measures of mental health in research with older adults who are incarcerated.

• DOI: 10.1108/ijph-08-2021-0085
• 发表时间: 2022-04-05
• 期刊: International journal of prisoner health
• 影响因子: 1.4

Fractured and delayed: A qualitative analysis of disruptions in care for gynecologic malignancies during incarceration.

骨折和延迟：对监禁期间妇科恶性肿瘤护理中断的定性分析。

• DOI: 10.1016/j.ygyno.2023.06.017
• 发表时间: 2023
• 期刊: Gynecologic oncology
• 影响因子: 4.7
• 作者: Burkett,WesleyC;Iwai,Yoshiko;Gehrig,PaolaA;Knittel,AndreaK
• 通讯作者: Knittel,AndreaK