Advancing womenâÂÂs health through research: the UNC WRHR Career Development Program

通过研究促进女性健康：北卡罗来纳大学 WRHR 职业发展计划

• 批准号: 10677529
• 负责人: Genevieve S. Neal-Perry
• 金额: $ 16.27万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-07-23 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10677529
• 关键词: Address; Area; Award; Cardiometabolic Disease; Collaborations; Communities; Cost Sharing; Discipline of Nursing; Ensure; Environment; Faculty; Foundations; Funding; Goals; Gynecologist; Health; Individual; Institution; Learning; Mentored Clinical Scientist Development Program; Mentors; Mentorship; Mood Disorders; North Carolina; Obesity; Pharmacy facility; Play; Pregnancy Complications; Program Development; Public Health; Reproductive Health; Research; Research Personnel; Resources; Role; Sexual Health; Social Work; Structure; Time; Translating; United States National Institutes of Health; Universities; Wages; Woman; Work; career; career development; clinical practice; clinically relevant; curriculum development; design; experience; faculty mentor; medical schools; medical specialties; next generation; peer; programs; risk minimization; substance use; success

PROJECT SUMMARY Obstetrician-gynecologists have an integral role to play in women’s reproductive health research. However, Ob- Gyn investigators have historically been underrepresented in the field, leading to critical missed opportunities to generate clinically-relevant research questions and to translate new findings into clinical practice. To address this important gap, we propose to re-establish the Women’s Reproductive Health Research Career Development Program at the University of North Carolina at Chapel Hill. Our aims are to catalyze early career development of promising Ob-Gyn clinician investigators and to support collaborative, cutting edge research that advances the field of women’s reproductive health. This program provides mentorship, structured career development activities, and at least 75% protected research time for two Ob-Gyn scholars annually. Building upon prior WRHR success (2005-2010), we have designed a program that addresses the needs of early career Ob-Gyn researchers. First, our scholars are embedded in a vibrant research environment within our Department of Ob- Gyn, which is supported by $14 million in annual research funding from NIH, other federal agencies, and foundations. Our scholars will conduct mentored research within emphasis areas designated in the application, at their intersection with women’s reproductive health. These include established research domains led by program faculty and supported by multiple NIH awards (complications of pregnancy, mood disorders and substance use, obesity and cardiometabolic disease, sexual and reproductive health). Opportunities to work in emerging areas with individual, funded investigators will also be offered. Second, our scholars will be mentored by experienced faculty. Mentorship committees are led by NIH-funded Ob-Gyn investigators and supported by collaborating faculty from the UNC Schools of Medicine, Public Health, Pharmacy, Nursing, and Social Work. Third, we have developed a robust career development curriculum that leverages existing K12/KL2 resources at UNC, while remaining distinct in its goals and purpose. This broader community of early career, research- oriented faculty provides opportunities for networking, shared learning, and peer-to-peer mentorship, and minimizes the risk of academic isolation. Fourth, our program has exceptional institutional support from the UNC School of Medicine. This includes a commitment of significant cost-sharing to ensure competitive junior faculty salaries, commensurate with specialty and subspecialty faculty in the department. Scholars will also have access to additional institutional resources through university-wide centers and institutes. The overarching goal of the UNC WRHR Program is to support promising early career Ob-Gyns during the often tenuous transition to research independence. Through access to an unparalleled group of experienced faculty mentors and the strength of its career development curriculum, our program will develop the next generation of independent NIH investigators in women’s reproductive health.

项目总结 妇产科医生在妇女生殖健康研究中发挥着不可或缺的作用。然而，Ob- 从历史上看，妇科调查人员在现场的代表性一直偏低，导致严重错失了 产生与临床相关的研究问题，并将新发现转化为临床实践。致信地址 这一重大差距，我们建议重新确立女性生殖健康研究的事业发展方向 北卡罗来纳大学教堂山分校的课程。我们的目标是促进早期职业发展 有前途的妇产科临床医生研究人员，并支持合作的尖端研究，推动 妇女生殖健康领域。该计划提供导师指导、有组织的职业发展 活动，每年至少75%保护两名妇产科学者的研究时间。在先前WRHR的基础上构建 成功(2005-2010)，我们设计了一项计划，满足早期职业妇产科的需求 研究人员。首先，我们的学者置身于我们Ob系内充满活力的研究环境中- GYN由美国国立卫生研究院、其他联邦机构提供的1400万美元年度研究资金支持，以及 基金会。我们的学者将在申请中指定的重点领域进行指导性研究， 在她们与女性生殖健康的交叉点。这些领域包括由 计划教职员工，并得到多个NIH奖项的支持(怀孕并发症、情绪障碍和 物质使用、肥胖和心脏代谢性疾病、性健康和生殖健康)。工作机会 新兴领域也将提供有个人、有资金的调查人员。第二，我们的学者将得到指导 由经验丰富的教职员工。导师委员会由美国国立卫生研究院资助的妇产科调查人员领导，并由 来自北卡罗来纳大学医学院、公共卫生、药学、护理和社会工作学院的合作教员。 第三，我们开发了一套健全的职业发展课程，利用现有的K12/KL2资源 在北卡罗来纳大学，同时保持其目标和宗旨的鲜明。这个更广泛的早期职业、研究社区- 以教师为导向提供网络、共享学习和点对点指导的机会，以及 将学术孤立的风险降至最低。第四，我们的项目得到了北卡罗来纳州大学的特殊机构支持 医学院。这包括承诺大量分担成本，以确保具有竞争力的初级教员 工资，与系中的专业和次级专业教职员工相称。学者们也将有机会 通过大学范围内的中心和研究所提供更多的机构资源。的首要目标是 北卡罗来纳大学WRHR计划是在通常微不足道的过渡期间支持有前途的早期职业Ob-GYN 研究独立性。通过接触到一群经验丰富的教师导师和 凭借其强大的职业发展课程，我们的计划将培养下一代独立的NIH 女性生殖健康方面的研究人员。

项目成果

Endocarditis, drug use and biological sex: A statewide analysis comparing sex differences in drug use-associated infective endocarditis with other drug-related harms.

心内膜炎、吸毒和生物性别：一项全州范围内的分析，比较了吸毒相关感染性心内膜炎与其他吸毒相关危害的性别差异。

• DOI: 10.1016/j.drugpo.2023.104280
• 发表时间: 2024
• 期刊: The International journal on drug policy
• 作者: McCrary,LMadeline;Cox,MaryE;Roberts,KateE;Knittel,AndreaK;Jordan,RobynA;Proescholdbell,ScottK;Schranz,AsherJ
• 通讯作者: Schranz,AsherJ

Experiences of menopause during incarceration.

在监禁期间更年期的经历。

• DOI: 10.1097/gme.0000000000001762
• 发表时间: 2021-03-11
• 期刊: Menopause (New York, N.Y.)
• 作者: Jaffe EF;Palmquist AEL;Knittel AK
• 通讯作者: Knittel AK

Ethical inclusion: Risks and benefits of research from the perspective of perinatal people with opioid use disorders who have experienced incarceration.

• DOI: 10.1371/journal.pone.0294604
• 发表时间: 2023
• 期刊: PLOS ONE
• 影响因子: 3.7
• 作者: Reddy, Julia;Black, Kristel;Bazemore, Keia;Jordan, Kiva;Jackson, Jamie B.;Knittel, Andrea K.
• 通讯作者: Knittel, Andrea K.

Standardized outcome measures of mental health in research with older adults who are incarcerated.

• DOI: 10.1108/ijph-08-2021-0085
• 发表时间: 2022-04-05
• 期刊: International journal of prisoner health
• 影响因子: 1.4

Fractured and delayed: A qualitative analysis of disruptions in care for gynecologic malignancies during incarceration.

骨折和延迟：对监禁期间妇科恶性肿瘤护理中断的定性分析。

• DOI: 10.1016/j.ygyno.2023.06.017
• 发表时间: 2023
• 期刊: Gynecologic oncology
• 影响因子: 4.7
• 作者: Burkett,WesleyC;Iwai,Yoshiko;Gehrig,PaolaA;Knittel,AndreaK
• 通讯作者: Knittel,AndreaK