Novel Wiring Catheter for Crossing Complex Chronic Total Occlusions

项目摘要/摘要 我们建议开发一种创新的导线导管系统，以可靠地指导内膜下交叉和再入。 在复杂动脉慢性完全闭塞(CTO)治疗中进入动脉真正管腔。建议数 系统将改进经皮冠状动脉和外周动脉治疗复杂CTO的技术 干预措施(PCI)。动脉粥样硬化推动冠状动脉、脑血管和外周血管的发展 动脉疾病。改进的CTO交叉设备和技术将允许更多的运营商执行这些操作 程序和改善病人护理。拟议的项目调查了一种新型制导再入的关键要素。 在会合动作中使用的导管系统，以提高精确度、速度、可靠性和安全性 逆行CTO经皮冠状动脉介入治疗。将开发和评估一个原型设备。

Project Summary/Abstract We propose to develop an innovative wiring catheter system to reliably direct subintimal crossing and re-entry into the artery true lumen during treatment of complex arterial chronic total occlusions (CTO). The proposed system will improve techniques for treating complex CTOs during percutaneous coronary and peripheral artery interventions (PCI). Atherosclerosis drives development of coronary artery, cerebrovascular, and peripheral arterial disease. Improved CTO crossing devices and techniques will allow more operators to perform these procedures and improve patient care. The proposed project investigates key elements of a novel guided re-entry catheter system to be used in a rendezvous maneuver to increase the precision, speed, reliability, and safety of retrograde CTO PCI crossing. A prototype device will be developed and evaluated.