Novel Wiring Catheter for Crossing Complex Chronic Total Occlusions

项目总结/摘要 我们建议开发一种创新的布线导管系统，以可靠地引导内膜下交叉和再进入 在治疗复杂动脉慢性完全闭塞（CTO）期间，将导管插入动脉真腔。拟议 该系统将改善经皮冠状动脉和外周动脉手术中治疗复杂CTO的技术 干预（PCI）。动脉粥样硬化驱动冠状动脉、脑血管和外周血管的发育 动脉疾病改进的CTO交叉设备和技术将允许更多的操作员执行这些操作 改善患者护理。拟议中的项目研究了一种新型制导重返大气层的关键要素 导管系统将用于会合机动，以提高精度、速度、可靠性和安全性， 逆行CTO PCI通过。将开发和评价一个原型装置。

Project Summary/Abstract We propose to develop an innovative wiring catheter system to reliably direct subintimal crossing and re-entry into the artery true lumen during treatment of complex arterial chronic total occlusions (CTO). The proposed system will improve techniques for treating complex CTOs during percutaneous coronary and peripheral artery interventions (PCI). Atherosclerosis drives development of coronary artery, cerebrovascular, and peripheral arterial disease. Improved CTO crossing devices and techniques will allow more operators to perform these procedures and improve patient care. The proposed project investigates key elements of a novel guided re-entry catheter system to be used in a rendezvous maneuver to increase the precision, speed, reliability, and safety of retrograde CTO PCI crossing. A prototype device will be developed and evaluated.