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Balloon Angioplasty Inflation Device

球囊血管成形术充气装置

基本信息

批准号：
10019316
负责人：
Nick Rydberg
金额：
$ 76.13万
依托单位：
MINNESOTA HEALTHSOLUTIONS CORPORATION
依托单位国家：
美国
项目类别：
财政年份：
2017
资助国家：
美国
起止时间：
2017-09-15 至 2021-11-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10019316
关键词：
Affect Algorithm Design Algorithms Amputation Angioplasty Animal Model Area Arteries Atherosclerosis Balloon Angioplasty Beds Bypass Cadaver Caliber Cardiovascular system Catheters Cause of Death Cells Cellular Structures Cessation of life Cholesterol Chronic Collaborations Computer software Coronary Coronary Arteriosclerosis Coronary artery Development Devices Disease Dissection Doctor of Philosophy Elasticity Electrical Engineering Engineering Event Family suidae Fluoroscopy Hand Hospitals Incidence Intervention Ischemic Stroke Lesion Life Style Liquid substance Location Maintenance Manuals Mechanics Medical Minnesota Modality Molecular North America Operative Surgical Procedures Oryctolagus cuniculus Outcome Perforation Performance Periodicity Peripheral arterial disease Persons Pharmaceutical Preparations Phase Physiologic pulse Principal Investigator Procedures Production Quality of life Recording of previous events Relaxation Research Resources Risk Factors Safety Specific qualifier value Specimen Stents Stress Structure Symptoms System Techniques Tissues Tube Ultrasonography United States Vascular Diseases Woman absorption artery occlusion common treatment design experience improved instrumentation loss of function medical schools novel novel therapeutics pressure product development programs prototype repaired research and development response restenosis software development tool

项目摘要

Project Summary/Abstract We propose the development of a novel balloon angioplasty inflation device for improving the safety and efficacy of balloon angioplasty. Atherosclerosis is associated with coronary artery disease, ischemic stroke and peripheral arterial disease. Percutaneous balloon angioplasty, often in conjunction with stent device deployment, has been associated with prolonged survival, increased quality of life and extended delay of restenosis. There exists great enthusiasm for percutaneous interventions to resolve atherosclerotic symptoms. Balloon inflation devices on the market do not adequately consider the molecular composition of the artery nor do they consider elasticity differences between arterial beds. The proposed project explores a novel technique to promote improved inflation performance during balloon angioplasty, resulting in less stress on the artery wall to achieve resultant luminal area. A production prototype device will be developed and evaluated.

项目摘要/摘要我们建议开发一种新型球囊血管成形术充气装置，以提高安全性和有效性。球囊血管成形术。动脉粥样硬化与冠状动脉疾病、缺血性中风和外周动脉疾病。经皮球囊血管成形术，通常结合支架装置的部署，与延长生存时间、提高生活质量和延长再狭窄的延迟有关。那里对经皮介入治疗以解决动脉粥样硬化症状有极大的热情。气球膨胀市场上的设备没有充分考虑动脉的分子组成，也没有考虑到动脉床之间的弹性差异。拟议的项目探索了一种新的技术来促进改进了球囊血管成形术期间的充气性能，从而减少了对动脉壁的应力以实现由此产生的管腔面积。将开发和评估一个生产原型设备。