Balloon Angioplasty Inflation Device

球囊血管成形术充气装置

• 批准号: 9410026
• 负责人: Nick Rydberg
• 金额: $ 22.5万
• 依托单位: MINNESOTA HEALTHSOLUTIONS CORPORATION
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-15 至 2018-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9410026
• 关键词: Affect; Algorithms; Amputation; Angioplasty; Area; Arteries; Atherosclerosis; Balloon Angioplasty; Beds; Biological; Bypass; Cadaver; Caliber; Cardiac; Cardiovascular system; Catheters; Cause of Death; Cells; Cellular Structures; Cessation of life; Cholesterol; Chronic; Collaborations; Computer software; Coronary; Coronary Arteriosclerosis; Coronary artery; Custom; Data; Development; Devices; Dissection; Doctor of Philosophy; Economic Inflation; Elasticity; Electrical Engineering; Engineering; Event; Family suidae; Hand; Incidence; Intervention; Ischemic Stroke; Lesion; Life Style; Liquid substance; Location; Maintenance; Mechanics; Medical; Minnesota; Modality; Molecular; North America; Operative Surgical Procedures; Outcome; Perforation; Performance; Periodicity; Peripheral arterial disease; Persons; Pharmaceutical Preparations; Phase; Physiologic pulse; Principal Investigator; Procedures; Process; Pulse Rates; Quality of life; Recording of previous events; Relaxation; Research; Research Personnel; Resources; Risk Factors; Safety; Sampling; Specimen; Stents; Stress; Stretching; Structure; Symptoms; Techniques; Tissues; Tube; United States; Universities; Vascular Diseases; absorption; base; common treatment; design; experience; improved; instrumentation; novel; pressure; product development; programs; prototype; research and development; response; restenosis

Project Summary/Abstract We propose the development of a novel balloon angioplasty inflation device for improving the safety and efficacy of balloon angioplasty. Atherosclerosis is associated with coronary artery disease, ischemic stroke and peripheral arterial disease. Percutaneous balloon angioplasty, often in conjunction with stent device deployment, has been associated with prolonged survival, increased quality of life and extended delay of restenosis. There exists great enthusiasm for percutaneous interventions to resolve atherosclerotic symptoms. Balloon inflation devices on the market do not adequately consider the molecular composition of the artery nor do they consider elasticity differences between arterial beds. The proposed project explores a novel technique to promote improved inflation performance during balloon angioplasty, resulting in less stress on the artery wall to achieve resultant luminal area. A prototype device will be developed and evaluated.

项目总结/摘要 我们建议开发一种新的球囊血管成形术充气装置，以提高安全性和 球囊血管成形术的疗效。动脉粥样硬化与冠状动脉疾病、缺血性中风和 外周动脉疾病经皮球囊血管成形术，通常与支架装置联合使用 部署，已与延长生存期，提高生活质量和延长延迟 再狭窄人们对经皮介入治疗动脉粥样硬化症状有很大的热情。 市场上的球囊膨胀装置没有充分考虑动脉的分子组成， 他们是否考虑了动脉床之间的弹性差异。该项目探索了一种新的技术 在球囊血管成形术期间促进改善的膨胀性能，导致动脉壁上的应力更小 以获得最终的管腔面积。将开发和评价一个原型装置。