Data Coordinating Core
Data Coordinating Core
批准号:
10483201
负责人:
DOUGLAS J WIEBE
金额:
$15.95万
依托单位国家:
美国
项目类别:
财政年份:
2019
资助国家:
美国
项目状态:
已结题
起止时间:
2019-09-30 至 2024-08-31
关键词:
AgeAlzheimer&aposs DiseaseBrainClinical DataClinical assessmentsCollaborationsCommon Data ElementCommunitiesDataData AnalysesData ElementData LinkagesData ReportingDevelopmentInformaticsInjuryInstitutionLaboratoriesLinkMindNational Institute of Neurological Disorders and StrokeNerve DegenerationNeurodegenerative DisordersParkinson DiseasePhasePopulationRecoveryResearchResearch PersonnelResearch Project GrantsSeveritiesSiteStandardizationSystemTraumatic Brain Injurycentral databasechronic traumatic encephalopathydata archivedata infrastructuredata repositorydata sharingdesigndigitaldigital repositoriespatient populationrepositoryresponse
中文摘要
数据协调核心
摘要
阻碍脑外伤相关神经变性(趋势)研究的一个关键因素是对
慢性创伤性脑病(CTE),对更广泛的人群考虑要少得多
颅脑损伤的神经病理效应。事实上,大多数趋势研究工作涉及单一的、本地化的人口
并在单个站点进行;此外,导出的数据在很大程度上无法向更广泛的人提供
社区。在相关的神经退行性疾病如阿尔茨海默氏症和
帕金森氏病,广泛的,协调的,多机构的努力,通过吸引
来自多个人群的数据。为了让TBI研究社区实现这一点,CONNECT-TBI数据
协调核心将专注于建立集中、标准化和可靠的所有
与研究项目有关的数据。通过与行政和智库核心部门的密切互动,
所有神经病理和临床数据的中央储存库将提供给所有授权的
调查人员。此核心旨在实施NINDS建立的公共数据元素(CDE)集
描述本地站点的TBI,并将这些数据汇编到中央数据库中。
英文摘要
Data Coordinating Core
SUMMARY
A key factor which has hindered research into TBI related neurodegeneration (TReND) is the narrow focus on
chronic traumatic encephalopathy (CTE) with far less consideration given to the broader group of
neuropathological effects of TBI. Indeed, most TReND research efforts involve a single, localized population
and are conducted at a single site; furthermore, the data derived is largely unavailable to the broader
community. As has been demonstrated in related neurodegenerative diseases such as Alzheimer’s and
Parkinson’s disease, broad, coordinated, and multi-institution efforts bolster the quality of research by drawing
data from multiple populations. To achieve this for the TBI research community, the CONNECT-TBI Data
Coordinating Core will focus its efforts on the establishing central, standardized, and reliable handling of all
data relating to the Research Projects. Through close interaction with the Administrative and Brain Bank Core,
a central repository of all neuropathological and clinical data will be made available to all authorized
investigators. This Core intends to implement the NINDS established sets of Common Data Elements (CDEs)
to characterize TBI at local sites and compile these data in the central database.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
CE19-001, The Penn Injury Science Center
-
批准号:10220751
-
项目类别:
-
资助金额:$84.02万
-
财政年份:2019
-
负责人:DOUGLAS J WIEBE
-
依托单位:
CE19-001, The Penn Injury Science Center
-
批准号:10054921
-
项目类别:
-
资助金额:$84.02万
-
财政年份:2019
-
负责人:DOUGLAS J WIEBE
-
依托单位:
Data Coordinating Core
-
批准号:10024095
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项目类别:
-
资助金额:$16.95万
-
财政年份:2019
-
负责人:DOUGLAS J WIEBE
-
依托单位:
CE19-001, The Penn Injury Science Center
-
批准号:10451463
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项目类别:
-
资助金额:$84.02万
-
财政年份:2019
-
负责人:DOUGLAS J WIEBE
-
依托单位:
CE19-001, The Penn Injury Science Center
-
批准号:10691934
-
项目类别:
-
资助金额:$1.0万
-
财政年份:2019
-
负责人:DOUGLAS J WIEBE
-
依托单位:
Data Coordinating Core
-
批准号:10241892
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项目类别:
-
资助金额:$16.48万
-
财政年份:2019
-
负责人:DOUGLAS J WIEBE
-
依托单位:
Injury and Trauma Research Training Program For Botswana
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批准号:9353891
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项目类别:
-
资助金额:$26.58万
-
财政年份:2016
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负责人:DOUGLAS J WIEBE
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依托单位:
Injury and Trauma Research Training Program For Botswana
-
批准号:9231865
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项目类别:
-
资助金额:$17.15万
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财政年份:2016
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负责人:DOUGLAS J WIEBE
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依托单位:
The geography of acute care
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批准号:8801812
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项目类别:
-
资助金额:$95.45万
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财政年份:2014
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负责人:DOUGLAS J WIEBE
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依托单位:
The Penn Violence and Injury Control Research Center
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批准号:9323820
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项目类别:
-
资助金额:$43.8万
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财政年份:2014
-
负责人:DOUGLAS J WIEBE
-
依托单位:
The Penn Violence and Injury Control Research Center
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批准号:9119503
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项目类别:
-
资助金额:$43.8万
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财政年份:2014
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负责人:DOUGLAS J WIEBE
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依托单位:
Determining National Injury Prevention Priorities
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批准号:8409786
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项目类别:
-
资助金额:$7.59万
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财政年份:2012
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负责人:DOUGLAS J WIEBE
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依托单位:
Determining National Injury Prevention Priorities
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批准号:8243058
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项目类别:
-
资助金额:$8.0万
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财政年份:2012
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负责人:DOUGLAS J WIEBE
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依托单位:
Studies of space-time activity patterns and fear in urban landscapes
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批准号:8528427
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项目类别:
-
资助金额:$12.6万
-
财政年份:2009
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负责人:DOUGLAS J WIEBE
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依托单位:
Studies of space-time activity patterns and fear in urban landscapes
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批准号:7921359
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项目类别:
-
资助金额:$13.51万
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财政年份:2009
-
负责人:DOUGLAS J WIEBE
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依托单位:
Studies of space-time activity patterns and fear in urban landscapes
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批准号:7741429
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项目类别:
-
资助金额:$13.17万
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财政年份:2009
-
负责人:DOUGLAS J WIEBE
-
依托单位:
Studies of space-time activity patterns and fear in urban landscapes
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批准号:8321617
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项目类别:
-
资助金额:$13.62万
-
财政年份:2009
-
负责人:DOUGLAS J WIEBE
-
依托单位:
Studies of space-time activity patterns and fear in urban landscapes
-
批准号:8137170
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项目类别:
-
资助金额:$13.7万
-
财政年份:2009
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负责人:DOUGLAS J WIEBE
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依托单位:
Alcohol, firearms, and adolescent gunshot injury risk
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批准号:7267109
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项目类别:
-
资助金额:$64.58万
-
财政年份:2005
-
负责人:DOUGLAS J WIEBE
-
依托单位:
Alcohol, firearms, and adolescent gunshot injury risk
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批准号:6968576
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项目类别:
-
资助金额:$68.61万
-
财政年份:2005
-
负责人:DOUGLAS J WIEBE
-
依托单位: