Data Coordinating Core

数据协调核心

• 批准号: 10241892
• 负责人: DOUGLAS J WIEBE
• 金额: $ 16.48万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-30 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10241892
• 关键词: Age; Alzheimer' s Disease; Brain; Clinical Data; Clinical assessments; Collaborations; Common Data Element; Communities; Data; Data Analyses; Data Element; Data Linkages; Data Reporting; Development; Informatics; Injury; Institution; Laboratories; Link; Mind; National Institute of Neurological Disorders and Stroke; Nerve Degeneration; Neurodegenerative Disorders; Parkinson Disease; Phase; Population; Recovery; Research; Research Personnel; Research Project Grants; Severities; Site; Standardization; System; Traumatic Brain Injury; central database; chronic traumatic encephalopathy; data archive; data infrastructure; data repository; data sharing; design; digital; digital repositories; patient population; repository; response

Data Coordinating Core SUMMARY A key factor which has hindered research into TBI related neurodegeneration (TReND) is the narrow focus on chronic traumatic encephalopathy (CTE) with far less consideration given to the broader group of neuropathological effects of TBI. Indeed, most TReND research efforts involve a single, localized population and are conducted at a single site; furthermore, the data derived is largely unavailable to the broader community. As has been demonstrated in related neurodegenerative diseases such as Alzheimer’s and Parkinson’s disease, broad, coordinated, and multi-institution efforts bolster the quality of research by drawing data from multiple populations. To achieve this for the TBI research community, the CONNECT-TBI Data Coordinating Core will focus its efforts on the establishing central, standardized, and reliable handling of all data relating to the Research Projects. Through close interaction with the Administrative and Brain Bank Core, a central repository of all neuropathological and clinical data will be made available to all authorized investigators. This Core intends to implement the NINDS established sets of Common Data Elements (CDEs) to characterize TBI at local sites and compile these data in the central database.

数据协调核心