Production of Secondary Metabolites by Plant Cell Suspension Cultures (Metavesse)
Production of Secondary Metabolites by Plant Cell Suspension Cultures (Metavesse)
批准号:
100961
负责人:
金额:
$12.56万
依托单位:
依托单位国家:
英国
项目类别:
Collaborative R&D
财政年份:
2011
资助国家:
英国
项目状态:
已结题
起止时间:
2011 至 --
中文摘要
Metavesse是一个研究从两个特别选择的植物细胞系中产生植物细胞次级代谢产物的项目。基于(-)-表儿茶素单体和特异性矢车菊苷配质低聚物的预计产量,从Evesse Apple品种中选择细胞系。这些细胞系预期用于化妆品和药妆。第一种细胞系被繁殖以产生高水平的(-)-表儿茶素的清洁和可再现的来源,第二种细胞系被繁殖以产生先前已显示出提供“表面”血管舒张和抗癌特性的特别鉴定的分子。这些细胞系用于生产标准化产品,这些产品在抗氧化剂、细胞坏死和细胞保护特性方面已成功表征。
英文摘要
Metavesse is a project which investigated the production of plant cell secondary metabolites derived from two specially selected plant cell lines. The cell lines were selected from amongst Evesse Apple vaieties based on their projected yield of (-)-epicatechin monomers and specific procyanidin oligomers. These cell lines are intended for use in cosmetics and cosmaceuticals. The first cell line was propagated to produce a clean and reproducible source of high levels of (-)-epciatechin and the second was propagated to produce specially identified molecules which had previously been shown to provide "surface" vasodilation and anti-cancer properties. The cell lines were used to produce standardised products which have been successfully characerised in terms of their anti-oxidant, cell necrosis and cell protection characteristics.
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