Admin Core

管理核心

• 批准号: 10493795
• 负责人: Corey S Cutler
• 金额: $ 5.12万
• 依托单位: DANA-FARBER CANCER INST
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-15 至 2027-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10493795
• 关键词: Basic Science; Biometry; Boston; Cell Therapy; Childhood; Chronic; Clinical Trials; Dana-Farber Cancer Institute; Disease; Goals; In Vitro; Individual; Minnesota; Monitor; Participant; Pediatric Hospitals; Pre-Clinical Model; Program Research Project Grants; Progress Reports; Regulation; Reporting; Research; Research Personnel; Transplantation; Universities; Vertebrates; human subject; in vivo; meetings; programs; success; synergism; transplantation therapy

Project Summary/Abstract – Admin Core This program project grant includes three Projects and four Cores, inclusive of this Administrative Core. We propose a highly collaborative scientific research program with clear and deep synergies between the basic science discovery, in vitro and in vivo pre-clinical modeling and a clinical trial. This collaborative program includes key investigators from the Divisions of Transplantation and Cellular Therapies, the Pediatric Transplantation Program, and the Department of Biostatistics at Dana Farber Cancer Institute, as well as investigators at Children’s Hospital Boston and the University of Minnesota. Several other centers are represented as contributors to individual Projects. To accomplish these goals, a centralized Administrative Core is proposed. This core will coordinate the efforts of all the investigators and collaborators involved in this Program; organize and conduct meetings of P01 participants and annual meetings of Program Project participants; prepare the necessary documents related to Program Project activities, including reports of Program Project investigator meetings, and prepare progress reports for official agencies; facilitate interaction between individual Projects and between Projects and Cores and monitor the progress of the individual Projects on a regular basis; maintain appropriate fiscal oversight of the Projects and Cores and prepare necessary fiscal reports of official agencies; and assure compliance with appropriate regulations regarding experimentation with human subjects and vertebrate animals. Coordinating all of these administrative facets will be a key to the success of this Program.

项目摘要/摘要-管理核心 该计划项目赠款包括三个项目和四个核心，包括本行政核心。我们 提出一个高度合作的科学研究计划，在基本的 科学发现、体外和体内临床前建模和临床试验。该合作计划包括 来自移植和细胞治疗部门，儿科移植部门的主要研究人员 项目，达纳法伯癌症研究所的生物统计学系，以及 波士顿儿童医院和明尼苏达大学。其他几个中心表示为 个人项目的贡献者。为了实现这些目标，提出了一个集中的行政核心。 该核心将协调参与该计划的所有研究人员和合作者的努力;组织 并召开P01参与者会议和计划项目参与者年度会议;准备 与计划项目活动相关的必要文件，包括计划项目调查员的报告 会议，并为官方机构编写进度报告;促进各个项目之间的互动 以及项目与核心之间的沟通，并定期监控各个项目的进度; 对项目和核心进行适当的财务监督，并准备官方机构的必要财务报告; 并确保遵守有关人类受试者实验的适当法规， 脊椎动物协调所有这些行政方面将是该方案成功的关键。