Admin Core

项目摘要/摘要-管理核心 该方案项目赠款包括三个项目和四个核心，包括这一行政核心。我们 提出一个高度协作的科学研究计划，在基础和基础之间具有明确和深入的协同作用 科学发现，体外和体内临床前建模和临床试验。该协作计划包括 来自移植和细胞治疗部门的主要研究人员，儿童移植 项目和达纳·法伯癌症研究所的生物统计部，以及 波士顿儿童医院和明尼苏达大学。其他几个中心表示为 单个项目的贡献者。为了实现这些目标，提出了一个集中的管理核心。 该核心将协调参与该计划的所有调查人员和合作者的努力；组织 并主持P01参与者会议和计划项目参与者年会；准备 与计划项目活动相关的必要文件，包括计划项目调查员的报告 举行会议，并为官方机构编写进度报告；促进各个项目之间的互动 以及项目和核心之间的关系，并定期监测个别项目的进展情况； 对项目和核心进行适当的财政监督，并编写必要的官方机构财政报告； 并确保遵守有关人体试验的适当法规和 脊椎动物。协调所有这些管理方面将是该计划成功的关键。

Project Summary/Abstract – Admin Core This program project grant includes three Projects and four Cores, inclusive of this Administrative Core. We propose a highly collaborative scientific research program with clear and deep synergies between the basic science discovery, in vitro and in vivo pre-clinical modeling and a clinical trial. This collaborative program includes key investigators from the Divisions of Transplantation and Cellular Therapies, the Pediatric Transplantation Program, and the Department of Biostatistics at Dana Farber Cancer Institute, as well as investigators at Children’s Hospital Boston and the University of Minnesota. Several other centers are represented as contributors to individual Projects. To accomplish these goals, a centralized Administrative Core is proposed. This core will coordinate the efforts of all the investigators and collaborators involved in this Program; organize and conduct meetings of P01 participants and annual meetings of Program Project participants; prepare the necessary documents related to Program Project activities, including reports of Program Project investigator meetings, and prepare progress reports for official agencies; facilitate interaction between individual Projects and between Projects and Cores and monitor the progress of the individual Projects on a regular basis; maintain appropriate fiscal oversight of the Projects and Cores and prepare necessary fiscal reports of official agencies; and assure compliance with appropriate regulations regarding experimentation with human subjects and vertebrate animals. Coordinating all of these administrative facets will be a key to the success of this Program.