Admin-Core-001

管理核心-001

• 批准号: 10496042
• 负责人: Carlo Maley
• 金额: $ 5.47万
• 依托单位: ARIZONA STATE UNIVERSITY-TEMPE CAMPUS
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-04-12 至 2023-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10496042
• 关键词: Admin; Core; 001

Admin Core Project Summary We propose to establish the Arizona Cancer and Evolution Center (ACE). Arizona State University will lead the Arizona Cancer and Evolution Center effort. Drs. Maley and Shibata, co-principal investigators, will direct the Center in collaboration with NCI program staff. ACE integrates a team of modelers, evolutionary biologists and cancer biologists with a successful track-record of collaborations. The objective of the Arizona Cancer and Evolution Center Administrative Core is to provide the necessary infrastructure for the overall organization and effective management of the Center to achieve the objectives of the CSBC and the NCI, as well as realize the scientific goals of the Center. The ACE Administrative Core will accomplish four Specific Aims during this funding period: Aim 1 Create and maintain a knowledgeable, skilled, and interdisciplinary leadership team that is connected to the research and the wider network; Aim 2 Design and implement a clear and effective communication plan across the Center; Aim 3 Identify and foster pilot projects; Aim 4 Solicit, coordinate, and respond to external advice for the scientific direction and opportunities for ACE. IMPACT: The Administrative Core will enable the Arizona Cancer and Evolution Center to transform current understanding and management of cancer by developing the theory, models, and measures of cancer that will be applicable and clinically relevant across cancers and species.

我们建议建立亚利桑那州癌症与进化中心（ACE）。亚利桑那州立大学将领导亚利桑那癌症和进化中心的工作。Drs。共同首席研究员Maley和Shibata将与NCI项目工作人员合作指导该中心。ACE整合了一个由建模师、进化生物学家和癌症生物学家组成的团队，有着成功的合作记录。亚利桑那癌症与进化中心行政核心的目标是为中心的整体组织和有效管理提供必要的基础设施，以实现CSBC和NCI的目标，并实现中心的科学目标。在此资助期内，ACE行政核心将实现四个具体目标：目标1：建立和维持一支知识渊博、技术熟练、跨学科的领导团队，与研究和更广泛的网络相联系；目标2：在中心范围内设计并实施清晰有效的沟通计划；目标3确定和促进试点项目；目标4征求、协调和回应外部建议，为ACE提供科学方向和机会。影响：行政核心将使亚利桑那州癌症和进化中心能够通过发展癌症的理论、模型和措施来改变目前对癌症的理解和管理，这些理论、模型和措施将适用于癌症和物种的临床相关。