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Northern New England Clinical and Translational Research Network

新英格兰北部临床和转化研究网络

基本信息

批准号：
10505149
负责人：
CLIFFORD JAMES ROSEN
金额：
$ 430万
依托单位：
MAINEHEALTH
依托单位国家：
美国
项目类别：
财政年份：
2017
资助国家：
美国
起止时间：
2017-07-03 至 2027-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10505149
关键词：
Acute Address Aging American Area Atherosclerosis Award Biometry COVID-19 COVID-19 pandemic Cardiovascular Diseases Centers of Research Excellence Chronic Clinical Clinical Data Clinical Investigator Clinical Research Clinical Trials Collaborations Communication Communities Community Health Community Outreach Coupled Cultural Diversity Data Development Diabetes Mellitus Disease Environment Evaluation Extramural Activities Faculty Food Analysis Foundations Funding Funding Mechanisms Goals Governing Board Grant Health Healthcare Human Papilloma Virus Vaccine Human Resources Immigrant Infrastructure Institutes Institution Investigation Leadership Learning Link Maine Malignant Neoplasms Mentors Mentorship Modeling Native Americans New England New Hampshire Obesity Opiate Addiction Opioid Passamaquoddy Tribe of Maine Patient Care Peer Review Penobscot Pilot Projects Play Population Populations at Risk Post-Acute Sequelae of SARS-CoV-2 Infection Predisposition Primary Health Care Public Health Publications Registries Research Research Design Research Infrastructure Research Personnel Research Support Reservations Resource Sharing Resources Role Rural Rural Health Rural Population Services Site Substance Use Disorder Substance abuse problem Sum Technology Toxic Environmental Substances Training Training Programs Translational Research Tribes United States Health Resources and Services Administration United States National Institutes of Health Universities Urban Population Vermont base career cohort community based research community engagement coronavirus disease diversity and inclusion epidemiology study flexibility food insecurity health communication health difference health disparity health equity improved innovation learning progression novel novel strategies patient oriented post-COVID-19 practice-based research network programs rural underserved rurality suburban communities technical report telehealth underserved community vaccine hesitancy

项目摘要

The long-term goal of the Northern New England Clinical and Translational Research Network (NNE-CTR), composed of MaineHealth, the University of Vermont, and the University of Southern Maine, is to sustain a clinical and translational research infrastructure that supports improvements in community health for northern New England inhabitants. Maine and Vermont have the oldest populations in the U.S. and that, coupled with rurality, predisposes residents to a range of disorders ranging from cancer to substance use disorders, food insecurity, obesity, diabetes and cardiovascular disease. In addition, northern New England has a growing underserved immigrant population, as well as a Native American population. Our communities have been challenged by the Covid-19 pandemic, and we are addressing these challenges by linking primary care practice centers with academic centers and developing innovative approaches to community-based research. During our first four years, the NNE-CTR has built a strong foundation for clinical research. We partnered with the oldest regional practice-based research network (PBRN), the Dartmouth Co-Op, and actively supported successful NIH program applications, including two COBREs, two NCI program grants, an infrastructure grant for a new Center for Biomedical Shared Resources, and a HRSA grant to build on the opioid treatment model pioneered in Vermont. The NNE-CTR PI is playing a leadership role in coordinating a national CTR network, including the CTR National COVID Cohort Collaborative (N3C), a registry to share clinical data on Covid-19 nationally, and the NIH-sponsored RECOVER trial, which will define the long-term sequelae of Covid-19. In this renewal, we plan to expand our collaborations both regionally and nationally, strengthen our PBRN, and embrace cultural diversity. We will strengthen Core resources that include: the Biostatistics, Epidemiology and Research Design Core, which will improve data capability and research navigation services; the Professional Development Core, which will offer an array of new educational and mentorship opportunities; the Pilot Projects Program, which will provide new and flexible funding mechanisms to offer more support for community-based projects; the Translational Research and Technology Core, offering state-of-the-art technologies and training for new investigators, and the Community Engagement and Outreach Core, which will build stronger bridges to underserved communities. We propose three specific aims: 1-Expand infrastructure and resources to address clinical and translational research needs in northern New England; 2- Strengthen clinical and translational research that addresses health equity and disparities encountered by at- risk populations, including expansion of clinical trial access, telehealth, and mentored training programs for new investigators; and 3-Accelerate regional and national collaborative initiatives within the IDeA networks and through NIH such as N3C and RECOVER. In sum, we will strengthen the NNE-CTR through continuous learning and improvement supported by the principles of diversity, inclusion, and equity.

新英格兰北部临床和转化研究网络（NNE-CTR）的长期目标，