NMR Core
NMR Core
批准号:
10506950
负责人:
ANGELA M. GRONENBORN
金额:
$96.87万
依托单位国家:
美国
项目类别:
财政年份:
2022
资助国家:
美国
项目状态:
未结题
起止时间:
2022-07-01 至 2027-04-30
关键词:
CapsidCell NucleusCellsCommunitiesComplexData AnalysesDetectionDiseaseEnvironmentEquipmentFluorineFrequenciesFutureGoalsHIVHIV-1InstitutionIntegraseIntegrase InhibitorsIntegration Host FactorsMagicMeasurementMeasuresMethodologyMethodsMolecular ConformationNMR SpectroscopyNatureNuclearNuclear ImportPhysiologicalPositioning AttributeProteinsProtocols documentationRecombinant ProteinsResearchResearch PersonnelResolutionResourcesSavingsSiteSpin LabelsStructureTechnologyTimeWorkbasebiophysical propertiescell typedata acquisitiondesignexperimental studyin vivoinhibitorinnovationinsightinstrumentationmagnetic fieldnew technologyprotein complexprotein structurescreeningsolid statesolid state nuclear magnetic resonancestructural biologytrafficking
中文摘要
点击翻译按钮获取中文摘要
英文摘要
NMR Core
The overall goal of the NMR Core is to provide state-of-the art capabilities for PCHPI researchers, for atomic-
level characterization of structure and dynamics of HIV-1 proteins and their complexes. To accomplish this goal,
we will take advantage of superb instrumentation resources, innovative experimental protocols, and unique
expertise developed during the past decade. Specific aims are designed to i) support PCHPI projects and extra-
center collaborators by providing cutting-edge solid-state NMR capabilities for HIV-1 research, and ii) develop
in-cell solution and solid state 19F NMR for HIV-1 research. The novel technologies developed by the NMR Core
will have major impact on HIV-1 cellular structural biology.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Molecular, Cellular and Behavioral Impact of the R203W PACS1 Syndrome Mutation
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批准号:10440654
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项目类别:
-
资助金额:$65.19万
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财政年份:2022
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负责人:ANGELA M. GRONENBORN
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依托单位:
Administrative Core
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批准号:10653244
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项目类别:
-
资助金额:$41.03万
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财政年份:2022
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负责人:ANGELA M. GRONENBORN
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依托单位:
Pittsburgh Center for HIV Protein Interactions (PCHPI)
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批准号:10506945
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项目类别:
-
资助金额:$496.16万
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财政年份:2022
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负责人:ANGELA M. GRONENBORN
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依托单位:
Pittsburgh Center for HIV Protein Interactions (PCHPI)
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批准号:10653242
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项目类别:
-
资助金额:$541.82万
-
财政年份:2022
-
负责人:ANGELA M. GRONENBORN
-
依托单位:
Administrative Core
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批准号:10506946
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项目类别:
-
资助金额:$39.23万
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财政年份:2022
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负责人:ANGELA M. GRONENBORN
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依托单位:
NMR Core
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批准号:10653256
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项目类别:
-
资助金额:$150.08万
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财政年份:2022
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负责人:ANGELA M. GRONENBORN
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依托单位:
Molecular, Cellular and Behavioral Impact of the R203W PACS1 Syndrome Mutation
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批准号:10612914
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项目类别:
-
资助金额:$65.49万
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财政年份:2022
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负责人:ANGELA M. GRONENBORN
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依托单位:
Structural characterization of interacting and aggregating cataract-associated crystallins
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批准号:10463640
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项目类别:
-
资助金额:$32.51万
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财政年份:2019
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负责人:ANGELA M. GRONENBORN
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依托单位:
MicroCal PEAQ-DSC
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批准号:10047566
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项目类别:
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资助金额:$13.25万
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财政年份:2019
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负责人:ANGELA M. GRONENBORN
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依托单位:
Structural characterization of interacting and aggregating cataract-associated crystallins
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批准号:10395057
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项目类别:
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资助金额:$5.85万
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财政年份:2019
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负责人:ANGELA M. GRONENBORN
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依托单位:
Structural characterization of interacting and aggregating cataract-associated crystallins
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批准号:10218184
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项目类别:
-
资助金额:$32.51万
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财政年份:2019
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负责人:ANGELA M. GRONENBORN
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依托单位:
Structural characterization of interacting and aggregating cataract-associated crystallins
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批准号:10018021
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项目类别:
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资助金额:$33.51万
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财政年份:2019
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负责人:ANGELA M. GRONENBORN
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依托单位:
Allosteric regulation of SIRT1 by a PACS-2 and DBC1 regulatory hub
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批准号:9750069
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项目类别:
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资助金额:$63.15万
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财政年份:2017
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负责人:ANGELA M. GRONENBORN
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依托单位:
Allosteric regulation of SIRT1 by a PACS-2 and DBC1 regulatory hub
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批准号:9976499
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项目类别:
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资助金额:$64.38万
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财政年份:2017
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负责人:ANGELA M. GRONENBORN
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依托单位:
Administrative Core
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批准号:8902483
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项目类别:
-
资助金额:$30.08万
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财政年份:2014
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负责人:ANGELA M. GRONENBORN
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依托单位:
750MHz Wide Bore NMR Spectrometer
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批准号:8334229
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项目类别:
-
资助金额:$200.0万
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财政年份:2013
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负责人:ANGELA M. GRONENBORN
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依托单位:
Conformation and Dynamics of Cataract Mutants of human gammaD crystallin
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批准号:8021928
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项目类别:
-
资助金额:$35.13万
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财政年份:2011
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负责人:ANGELA M. GRONENBORN
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依托单位:
Conformation and Dynamics of Cataract Mutants of human gammaD crystallin
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批准号:8391719
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项目类别:
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资助金额:$33.22万
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财政年份:2011
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负责人:ANGELA M. GRONENBORN
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依托单位:
Conformation and Dynamics of Cataract Mutants of human gammaD crystallin
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批准号:8209151
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项目类别:
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资助金额:$35.05万
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财政年份:2011
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负责人:ANGELA M. GRONENBORN
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依托单位:
Conformation and Dynamics of Cataract Mutants of human gammaD crystallin
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批准号:8599776
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项目类别:
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资助金额:$23.52万
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财政年份:2011
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负责人:ANGELA M. GRONENBORN
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依托单位:
海外基金