Pilot Projects Program

试点项目计划(PPP)对临床和转化性研究的发展和支持至关重要 西弗吉尼亚临床与转化科学研究所(WVCTSI)。PPP提供基础设施 让早期调查人员(ESIS)走上提供有意义的研究以积极影响WEST的道路 弗吉尼亚人，在快速发展和变化的健康相关领域。虽然合格的研究人员存在于 在国家，PPP提供了一个平台，以匹配WVCTSI伙伴机构内部和之间的专业知识。至 为了实现其目标，PPP将(1)提供创新的资金机制，以促进临床和翻译 研究，(2)努力提高该州临床和转化性研究的质量和影响，以及(3) 刺激ESI发展。为了实现这些目标，公私合作伙伴关系将提供几种筹资机制，以加强 以开放资助为主要支持机制的临床和转化性研究 由调查员发起的研究。两个新的PPP资助机会将建立基于团队的科学倡议 (长凳到床边助学金)，并通过研究员助学金计划创建一个新的职业发展倡议。 新的快速反应拨款将允许灵活地针对州内新出现的健康问题，并 在更短的时间内为有价值的项目提供资金。促进经济发展和社会进步 新的医疗相关技术的商业化是新的启动赠款计划的重点， JUMPSTART助学金，提供资金以完成手稿或为校外获得关键的初步数据 批准申请。如果PPP资助机制的申请集中在WVCTSI，将获得优先考虑 健康优先领域由ESI和/或临床医生领导，来自合作伙伴网站，或使用基于实践的 研究网络。将为提供医科学生研究的申请者提供奖励 经验。我们还将提供一种A1机制，使调查人员能够找到有希望的项目，但不能 将提供指导，并有机会重新提交改进后的提案。此外, 提高伙伴机构调查员提交的试点项目的成功率是一个优先事项。事实上， WVCTSI伙伴机构之间发展的信任和同志情谊将促进实施有影响力的 WV科学通过购买力平价。PPP将与其他WVCTSI核心协同工作，指导和培训 临床和转化性研究中的网络调查人员，以提高临床和研究的质量和影响 在西弗吉尼亚州进行翻译研究，并增加WVCTSI调查人员在确保校外安全方面的成功 资金问题。

The Pilot Project Program (PPP) is crucial to the development and support of clinical and translational research for the West Virginia Clinical and Translational Science Institute (WVCTSI). The PPP provides the infrastructure to set early-stage investigators (ESIs) on the path that will provide meaningful research to positively impact West Virginians, in rapidly advancing and changing health-related fields. While qualified researchers exist within the state, the PPP provides a platform to match expertise within and across WVCTSI partner institutions. To accomplish its goals, the PPP will (1) provide innovative funding mechanisms to facilitate clinical and translational research, (2) work to improve the quality and impact of clinical and translational research in the state, and (3) stimulate ESI development. Toward these goals, the PPP will provide several funding mechanisms to enhance clinical and translational research with the Open Grant serving as a primary mechanism for supporting investigator-initiated research. Two new PPP funding opportunities will establish team science-based initiatives (Bench-to-Bedside Grants) and create a new career development initiative through the Fellows Grant program. The new Rapid Response Grant will allow for flexibility in targeting emerging health issues within the state and getting funding to meritorious projects in a shortened time frame. Promoting the development and commercialization of new medically-related technology is the focus of the novel Launch Grant program, with the Jumpstart Grant providing funding to complete a manuscript or obtain key preliminary data for an extramural grant application. Applications for PPP funding mechanisms will receive priority if they are focused on WVCTSI health priority areas, are led by an ESI and/or a clinician, are from a partner site, or use the Practice-Based Research Network. Incentives will be provided for applications that provide a medical student research experience. We will also provide an A1 mechanism whereby investigators with promising projects that fall short of the funding line will be provided mentoring and the opportunity to resubmit an improved proposal. In addition, improving the success rate of pilot projects submitted by partner institution investigators is a priority. Indeed, the trust and camaraderie developed among WVCTSI partner institutions will facilitate implementation of impactful WV science through the PPP. The PPP will work synergistically with other WVCTSI Cores to mentor and train network investigators in clinical and translational research to improve the quality and impact of clinical and translational research in West Virginia and increase the success of WVCTSI investigators in securing extramural funding.