Pilot Projects Program

试点项目计划 (PPP) 对于临床和转化研究的发展和支持至关重要 西弗吉尼亚临床和转化科学研究所 (WVCTSI)。 PPP 提供基础设施 让早期研究人员 (ESI) 走上提供有意义的研究以对西方产生积极影响的道路 弗吉尼亚人在快速发展和变化的健康相关领域。虽然合格的研究人员存在于 州，PPP 提供了一个平台来匹配 WVCTSI 合作机构内部和之间的专业知识。至 为了实现其目标，PPP 将 (1) 提供创新的融资机制，以促进临床和转化 研究，(2) 努力提高本州临床和转化研究的质量和影响，以及 (3) 刺激ESI发展。为了实现这些目标，PPP 将提供多种融资机制来加强 以开放资助为主要支持机制的临床和转化研究 研究者发起的研究。两项新的 PPP 融资机会将建立基于科学的团队举措 （从实验室到临床的补助金），并通过研究员补助金计划制定新的职业发展计划。 新的快速反应补助金将允许灵活地针对州内新出现的健康问题， 在较短的时间内为有功绩的项目获得资金。促进发展和 新的医疗相关技术的商业化是新启动资助计划的重点， Jumpstart Grant 提供资金来完成手稿或获取校外的关键初步数据 拨款申请。如果 PPP 融资机制的申请重点关注 WVCTSI，则将获得优先权 健康优先领域，由 ESI 和/或临床医生领导，来自合作伙伴站点，或使用基于实践的 研究网．将为提供医学生研究的申请提供激励 经验。我们还将提供一个A1机制，让那些有希望但达不到要求的项目的调查人员 资金额度的一部分将获得指导和重新提交改进提案的机会。此外， 提高合作机构研究人员提交的试点项目的成功率是当务之急。确实， WVCTSI 合作伙伴机构之间建立的信任和友情将促进有影响力的实施 通过 PPP 进行西弗吉尼亚州科学。 PPP 将与其他 WVCTSI 核心协同工作，提供指导和培训 临床和转化研究网络研究者，以提高临床和转化研究的质量和影响 西弗吉尼亚州的转化研究，并提高 WVCTSI 调查人员在确保校外安全方面的成功率 资金。

The Pilot Project Program (PPP) is crucial to the development and support of clinical and translational research for the West Virginia Clinical and Translational Science Institute (WVCTSI). The PPP provides the infrastructure to set early-stage investigators (ESIs) on the path that will provide meaningful research to positively impact West Virginians, in rapidly advancing and changing health-related fields. While qualified researchers exist within the state, the PPP provides a platform to match expertise within and across WVCTSI partner institutions. To accomplish its goals, the PPP will (1) provide innovative funding mechanisms to facilitate clinical and translational research, (2) work to improve the quality and impact of clinical and translational research in the state, and (3) stimulate ESI development. Toward these goals, the PPP will provide several funding mechanisms to enhance clinical and translational research with the Open Grant serving as a primary mechanism for supporting investigator-initiated research. Two new PPP funding opportunities will establish team science-based initiatives (Bench-to-Bedside Grants) and create a new career development initiative through the Fellows Grant program. The new Rapid Response Grant will allow for flexibility in targeting emerging health issues within the state and getting funding to meritorious projects in a shortened time frame. Promoting the development and commercialization of new medically-related technology is the focus of the novel Launch Grant program, with the Jumpstart Grant providing funding to complete a manuscript or obtain key preliminary data for an extramural grant application. Applications for PPP funding mechanisms will receive priority if they are focused on WVCTSI health priority areas, are led by an ESI and/or a clinician, are from a partner site, or use the Practice-Based Research Network. Incentives will be provided for applications that provide a medical student research experience. We will also provide an A1 mechanism whereby investigators with promising projects that fall short of the funding line will be provided mentoring and the opportunity to resubmit an improved proposal. In addition, improving the success rate of pilot projects submitted by partner institution investigators is a priority. Indeed, the trust and camaraderie developed among WVCTSI partner institutions will facilitate implementation of impactful WV science through the PPP. The PPP will work synergistically with other WVCTSI Cores to mentor and train network investigators in clinical and translational research to improve the quality and impact of clinical and translational research in West Virginia and increase the success of WVCTSI investigators in securing extramural funding.