Pilot Projects Program

试点项目计划

• 批准号: 10213759
• 负责人: GARY O RANKIN
• 金额: $ 27.03万
• 依托单位: WEST VIRGINIA UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-08-15 至 2022-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10213759
• 关键词: Address; Appalachian Region; Area; Award; Cardiovascular Diseases; Chronic lung disease; Clinical; Clinical Investigator; Clinical Research; Clinical Sciences; Collaborations; Community Outreach; Development; Diffusion; Education; Epidemic; Extramural Activities; Fellowship; Funding; Funding Agency; Funding Opportunities; Future; Goals; Health; Health Benefit; Health Priorities; Hepatitis C; Infrastructure; Institutes; Institution; Intellectual Property; Investments; Legal patent; Malignant Neoplasms; Measurable; Medical Residency; Mentors; Mission; Outcome; Pilot Projects; Play; Population; Preparation; Principal Investigator; Productivity; Publications; Request for Applications; Research; Research Personnel; Research Proposals; Role; Rural Community; Science; Scientist; Secure; Series; Translational Research; Translations; United States National Institutes of Health; Universities; West Virginia; addiction; career; clinically relevant; commercialization; community engagement; design; experience; feasibility testing; improved; innovation; invention; multidisciplinary; novel; programs; success; translational scientist

Clinical and translational (C/T) research plays a vital role within the West Virginia Clinical and Translational Institute (WVCTSI) network. The overall goal of the Pilot Project Core (PPC) is to increase the number of externally-funded C/T investigators across the state addressing West Virginia health issues. To achieve this goal, the PPC will accomplish three specific aims: 1) provide infrastructure supporting competitive pilot funding opportunities for early stage (ESI) and new investigators (NI) with subsequent mentored progression to project completion, publication, and external funding application, 2) advance intra- and inter-state collaborative research endeavors to address WVCTSI priority health areas within WV as well as throughout the Appalachian region, and 3) implement the Launch Pad Pilot Program to maximize opportunities for commercialization of novel science. In Aim 1, the PPC will solicit and rigorously review relevant C/T research applications from WVCTSI investigators. Applicants will receive intensive mentoring from project initiation through publication preparation and subsequent extramural funding of applications. Emphasis will be placed on new investigators (investigators with no independent - R01 level - funding) and Early Stage Investigators (< 10 years into their career post education, including medical residency and fellowships). PPC will engage successful senior investigators as two Scientific Senior Advisors (one a clinician scientist, the other a translational scientist). These Senior Advisors will aid PPC in its mentoring mission by working closely with new and early stage investigators to assure research productivity through the creation of appropriate mentoring teams in collaboration with the Professional Development Core. The PPC will prioritize pilot awards to promote clinical projects, particularly those conducted in rural communities. In Aim 2, the PPC will promote intra- and inter-state collaborative research efforts that target WVCTSI priority health areas through specific “requests for applications” and programs that require or include principal investigators from more than one WVCTSI partner. The PPC will also assist other Cores (e.g. Community Engagement and Outreach) with their focused research programs through facilitating application solicitation and review. Aim 3 will focus on implementing the “Launch Pad” pilot program that was tested for feasibility during Year 4 of the initial funding cycle. Launch Pad is an innovative program intended to accelerate the translation of intellectual property developed by researchers within the WVCTSI network into realized inventions and patents, thereby broadening the potential sources of funding. Collectively, the PPC initiatives will significantly advance the conduct of C/T research in West Virginia to benefit the health of all West Virginians and regional Appalachian populations.

临床和转化（C/T）研究在西弗吉尼亚州临床和转化研究中心发挥着至关重要的作用。 研究所（WVCTSI）网络。核心试点项目的总体目标是增加 外部资助的C/T调查员在整个国家解决西弗吉尼亚州的健康问题。实现 为了实现这一目标，PPC将实现三个具体目标：1） 提供支持竞争性试点的基础设施 为早期阶段（ESI）和新研究者（NI）提供资助机会，随后指导进展， 项目完成、出版和外部资金申请，2）推进国家内部和国家间的合作 研究努力解决西弗吉尼亚州以及整个阿巴拉契亚地区的WVCTSI优先健康领域 3）实施发射台试点计划，以最大限度地增加新技术商业化的机会。 科学在目标1中，PPC将征求并严格审查相关的C/T研究申请， WVCTSI调查员。申请人将从项目启动到 出版物的准备和随后的校外资助的应用程序。重点将 安置在新研究者（无独立研究者-R 01级-资金）和早期阶段 研究者（职业后教育< 10年，包括医疗住院医师和研究员）。PPC将 聘请成功的高级研究者担任两名科学高级顾问（一名是临床科学家，另一名是 翻译科学家）。这些高级顾问将通过与新的 和早期研究人员，通过建立适当的指导团队来确保研究生产力 与专业发展核心合作。PPC将优先考虑试点奖励，以促进 临床项目，特别是在农村社区开展的项目。在目标2中，PPC将促进内部 州际合作研究工作，通过具体的“要求， 申请”和需要或包括来自一个以上WVCTSI合作伙伴的主要研究者的计划。 PPC还将协助其他核心（例如社区参与和外联）进行重点研究 通过促进申请征集和审查来开展项目。目标3将侧重于实施“启动 在初始供资周期的第4年期间测试可行性的“PAD”试点方案。发射台是一个 创新计划，旨在加快由研究人员开发的知识产权的翻译， WVCTSI的网络转化为已实现的发明和专利，从而扩大了潜在的资金来源。 总的来说，PPC计划将大大推进西弗吉尼亚州的C/T研究， 所有西弗吉尼亚人和阿巴拉契亚地区人口的健康。