West Virginia IDeA Network of Biomedical Research Excellence (WV-INBRE)

描述（由申请人提供）： 西弗吉尼亚州是一个在获得赠款资金方面成功率历史最低的州， 美国国立卫生研究院，并已被指定为一个IDEA国家。在此更新申请中，马歇尔大学（MU）与西弗吉尼亚大学（WVU）合作，将继续建立在西弗吉尼亚州IDEA生物医学研究卓越网络（WV-INBRE）的成功基础上，以帮助整个网络开发生物医学研究基础设施和能力，并为合作机构的本科生和研究生提供生物医学研究经验。MU与WVU合作，将继续作为由13个主要本科院校（PUI）组成的研究网络的牵头机构。WV-INBRE的多学科主题将是细胞和分子生物学，重点是慢性疾病（癌症、心血管疾病、糖尿病和肥胖相关疾病）。支持该网络活动的将是行政、生物信息学和基因组学核心，这些核心的建立是为了促进研究进展、指导和培训以及牵头机构和伙伴机构的研究人员和学生的职业发展。该网络的研究将得到主要PUI研究奖，教师研究发展奖（FRDAs），天然产物研究中心，基因组学核心和慢性病研究计划试点项目奖的支持。将扩大与WV COBREs和健康科学与技术学院（HSTA; NIH资助的SEPA计划）的联系，并提议与WV IDEA-CTR计划建立联系，为PUI学生提供研究机会，包括夏季研究计划和HSTA研究生计划，以帮助这些学生进入健康相关的研究职业。HSTA高中科学教师和合作机构的教师研究员也将提供夏季研究机会，在领导和网络机构。通过提供讲习班，研讨会，研究培训和指导，并获得最先进的核心设施，WV-INBRE将有助于提高WV劳动力的科学和技术知识和技能基础。

DESCRIPTION (provided by applicant): West Virginia is a State that has had a historically low success rate in obtaining grant funds from the National Institutes of Health and has been designated as an IDeA state. In this renewal application, Marshall University (MU), in partnership with West Virginia University (WVU), will continue to build on the success of the West Virginia IDeA Network of Biomedical Research Excellence (WV-INBRE) to help develop biomedical research infrastructure and capacity throughout the network and provide biomedical research experiences for undergraduate and graduate students from the partner institutions. MU, in partnership with WVU, will continue to serve as lead institutions to a research network consisting of thirteen primarily undergraduate institutions (PUIs). The multi-disciplinary theme for WV-INBRE will be cellular and molecular biology with an emphasis on chronic disease (cancer, cardiovascular disease, diabetes and obesity-related illness). Supporting the activities of the network will be the Administrative, Bioinformatics and Genomics Cores which have been established to facilitate research progress, mentoring and training, and career development of investigators and students at the lead and partner institutions. Research in the network will be supported by major PUI research awards, Faculty Research Development Awards (FRDAs), and Center for Natural Products Research, Genomics Core and Chronic Disease Research Program pilot project awards. Ties to WV COBREs and the Health Sciences and Technology Academy (HSTA; an NIH-funded SEPA program) will be expanded and ties initiated to the WV IDeA-CTR Programs are proposed to provide research opportunities for PUI students, including the summer research program and HSTA graduate initiative, to help serve as a pipeline for these students into health-related research careers. HSTA high school science teachers and partner institution faculty fellows will also be provided summer research opportunities at the lead and network institutions. Through providing workshops, seminars, research training and mentoring, and access to state-of-the-art core facilities, WV-INBRE will help enhance the science and technology knowledge and skill base of the WV workforce.