Polymer nanodiscs

聚合物纳米圆盘

• 批准号: FT200100185
• 负责人: A/Prof Markus Muellner
• 金额: $ 68.3万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: ARC Future Fellowships
• 财政年份: 2021
• 资助国家: 澳大利亚
• 起止时间: 2021-02-01 至 2025-07-25
• 项目状态: 未结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/FT200100185
• 关键词: Polymer; nanodiscs

This project aims to produce disc-shaped polymer nanomaterials by utilising a new self-assembly concept based on oppositely charged polymers. This project expects to generate a modular technology that allows synthesis and control over the geometry and functionality of polymer nanoparticles. This level of control will permit a precise investigation of polymer nanodisc properties for nanomedicine applications. Expected outcomes of this project will be the fundamental understanding of how nanoparticle geometry affects particle-cell interaction and how nanoscale polymer discs can be used to mimic biological nanoparticles in shape and function.

该项目旨在通过利用基于带相反电荷的聚合物的新的自组装概念来生产盘形聚合物纳米材料。该项目预计将产生一种模块化技术，允许合成和控制聚合物纳米颗粒的几何形状和功能。这种水平的控制将允许精确的调查聚合物nanodisc性能的纳米医学应用。该项目的预期成果将是对纳米颗粒几何形状如何影响颗粒-细胞相互作用以及纳米级聚合物圆盘如何用于模拟生物纳米颗粒的形状和功能的基本理解。