FASEB SRC: The Gastrointestinal Tract XIX Conference: Making and Breaking a Gut

项目概要/摘要 该申请请求对题为“胃肠道”的FASEB科学研究会议的部分支持 道十九：制造和打破肠道”，定于8月7日至12日，2022年在汽船泉，有限公司。 这次会议将召集一批不同的发言者，包括许多妇女，代表人数不足的少数民族， 和年轻的研究人员，讨论胃肠道的生物学及其在环境中的失调 疾病。一个主题演讲加上八个讲座将解决胃肠道干细胞稳态 以及对损伤/疾病、营养和代谢的响应的可塑性，使用GI类器官的新方法， 微生物群-肠-脑轴，上皮生理学，微生物稳态和疾病发病机制，粘膜 炎症和IBD，以及癌症。大会将预留充裕时间供与会者讨论， 将优先提供未公布的数据。也将有两个海报会议以及几个 为早期职业调查员和受训人员举办职业发展活动，并提供晋升机会 这些代表该领域未来的个人的知名度。我们已经建立了一个创新的 该计划由在地理信息相关研究领域具有不同专业知识的领导者承诺参与。 总的来说，在一个亲密和隐蔽的环境中，鼓励科学家之间的非正式互动， 我们提供了一个创新的方法来交流思想和科学的综合，这将推动 地理信息系统研究的前沿。该会议将产生很大的影响，因为该计划涵盖基础科学 这一发现对胃肠道健康和疾病具有临床意义。因此，预计会议将提供 新的见解，不仅对基本的胃肠道生理学，神经生物学，发育生物学， 微生物学，而且如何治疗，并最终治愈，各种各样的消化系统疾病状态。

Project summary/abstract This application requests partial support for a FASEB Scientific Research Conference entitled “Gastrointestinal Tract XIX: Making and Breaking the Gut” that is scheduled for August 7-12, 2022 in Steamboat Springs, CO. The meeting will convene a diverse group of speakers, including many women, underrepresented minorities and young investigators, to discuss the biology of the gastrointestinal tract and its dysregulation in the setting of disease. A keynote address plus eight lecture sessions will address gastrointestinal stem cell homeostasis and plasticity in response to injury/disease, nutrition and metabolism, novel approaches using GI organoids, the microbiota-gut-brain axis, epithelial physiology, microbial homeostasis and disease pathogenesis, mucosal inflammation and IBD, and cancer. Ample time will be set aside for discussions amongst participants, and the presentation of unpublished data will be prioritized. There will also be two poster sessions as well as several career development activities for early career investigators and trainees, as well as opportunities to promote the visibility of these individuals who represent the future of the field. We have assembled an innovative program with committed participation from leaders with diverse expertise within GI-related research fields. Overall, in an intimate and secluded setting that encourages informal interactions between scientists at all levels, we provide an innovative approach to the exchange of ideas and synthesis of science that will move the field of GI research forward. The conference will have high impact as the program spans basic science discovery to clinical significance for GI health and disease. It is therefore expected that the meeting will provide new insights not only into basic gastrointestinal physiology, neurobiology, developmental biology and microbiology, but also how to treat, and ultimately cure, a wide variety of digestive disease states.