2022 American Society for Matrix Biology Workshop on Fibroblasts: The Many Faces of Fibroblasts

项目摘要 2000年成立的美国基质生物学学会（ASMB），推动细胞外基质领域的研究 (ECM)生物学促进知识的发展，并激发以ECM为中心的科学的转化，以改善人类健康 面对衰老和疾病。ASMB支持类似规模和范围的两年期讲习班， 戈登研究会议和Keystone研讨会。这些讲习班的总体目标是 是深入研究关键的主题，是及时的，特别是相关的矩阵生物学。2022年的主题 ASMB研讨会是成纤维细胞的许多面孔和功能。此R13应用程序的具体目标 是（目的1）传播和分享有关成纤维细胞生物学的新知识，他们的异质性， 表型分化，以及如何定量测量成纤维细胞的结果;（目的2）促进 （三）促进青年科学家的教育成长和职业发展;（四）促进妇女和未成年人的职业发展。 代表少数民族。为了实现这些目标，我们召集了一批世界各地的专家， 成纤维细胞生物学，从细胞概况和发育起源到它们的异质性和多样性， 疾病进展。青年科学家将在现有的会谈中尽可能突出 从摘要中选出，并在会议日程中包括一次指导会议和三次旅行奖励 资助年轻的研究人员参加会议。最后，妇女的代表性 少数民族科学家在受邀演讲者和主持人名单中的比例为59%。这些目的是 符合NIH的使命和R13资助机制的目标。R13基金将 主要用于部分支持主旨发言人的差旅和住宿费用、差旅奖励，以及 会议租赁和A/V支持，以确保会议成功。

PROJECT SUMMARY The American Society for Matrix Biology (ASMB), founded in 2000, promotes the field of extracellular matrix (ECM) biology to advance knowledge and inspire translation of ECM-centric science to improve human health in the face of aging and disease. ASMB supports biennial workshops that are of similar scale and scope to individual Gordon Research Conferences and Keystone Symposia. The overarching goals of these workshops are to delve into key topics that are timely and of particular relevance to matrix biology. The theme of the 2022 ASMB Workshop is the Many Faces and Functions of Fibroblasts. The specific aims of this R13 application are (Aim 1) to disseminate and share new knowledge about fibroblast biology, their heterogeneity, the patterns of phenotypic differentiation, and how to quantitatively measure fibroblast outcomes; (Aim 2) to promote the educational growth and careers of young scientists; and (Aim 3) to promote the careers of women and under- represented minorities. To achieve these aims we have assembled a slate of world experts in the field of fibroblast biology, from cellular profiling and developmental origins to their heterogeneity and diversity in disease progression. Young scientists will be featured as prominently as possible in the available talks selected from abstracts and a mentoring session is included in the meeting schedule and three travel awards are being offered to support young investigators’ travel to the conference. Finally, the representation of women and minority scientists in the slate of invited speakers and moderators altogether is 59%. These Aims are consistent with the mission of the NIH and the goals of the R13 funding mechanism. R13 funds will be primarily allocated to partially support travel and housing expenses of keynote speakers, travel awards, and conference rental and A/V support to ensure a successful meeting.