Transforming our understanding of the chemical exposome

改变我们对化学暴露组的理解

• 批准号: FL200100028
• 负责人: Prof Jochen Mueller
• 金额: $ 203.13万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Australian Laureate Fellowships
• 财政年份: 2021
• 资助国家: 澳大利亚
• 起止时间: 2021-01-04 至 2026-01-03
• 项目状态: 未结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/FL200100028
• 关键词: Transforming; our; understanding; chemical; exposome

Despite many benefits associated with the use of chemicals, there is consensus that their accelerated production and use is increasingly affecting environmental health. Effective tools to understand spatiotemporal trends and factors that drive chemical exposure are urgently needed. This project aims to develop these tools by combining established programs in systematic sampling and archiving with advanced informatics and analytical techniques. The project expects to identify emerging chemicals of concern, assess factors that affect exposure and model exposure based on chemical production, use and fate. Outcomes will support evidence-based regulation and management of chemicals to minimise adverse impacts of chemical exposure in Australia.

尽管化学品的使用带来了许多好处，但人们一致认为，化学品的加速生产和使用正在日益影响环境健康。迫切需要有效的工具来了解时空趋势和驱动化学品接触的因素。该项目旨在通过将系统采样和存档方面的既定方案与先进的信息学和分析技术相结合，开发这些工具。该项目预计将确定新出现的令人关切的化学品，评估影响接触的因素，并根据化学品的生产、使用和转归建立接触模型。其成果将支持以证据为基础的化学品监管和管理，以最大限度地减少澳大利亚化学品暴露的不利影响。