Microflow ultra high pressure liquid chromatography - high resolution mass spectrometry for chemical exposure monitoring

用于化学品暴露监测的微流超高压液相色谱-高分辨率质谱法

• 批准号: LE140100129
• 负责人: Prof Jochen Mueller
• 金额: $ 16.6万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Infrastructure, Equipment and Facilities
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2015-05-08
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LE140100129
• 关键词: Microflow; ultra; pressure; liquid; chromatography

Microflow ultra high pressure liquid chromatography – high resolution mass spectrometry for chemical exposure monitoring: Identifying new chemicals of interest in environmental or biological samples is the first critical step toward understanding their impact to human and environment. A state-of-the-art microflow ultra high performance liquid chromatography high resolution mass spectrometer is fundamental to extend our research capabilities to new environmental contaminants and environmental exposure biomarkers, as well as consumption biomarkers of new illicit drugs and their metabolites. This instrument will fill an important gap in our capacity to link health/ecological risk to unknown chemicals and will allow interdisciplinary researchers to advance work in environmental toxicology, chemistry and forensics.

微流超高压液相色谱-高分辨率质谱法用于化学品暴露监测：识别环境或生物样品中感兴趣的新化学品是了解其对人类和环境影响的第一个关键步骤。最先进的微流超高效液相色谱高分辨率质谱仪是将我们的研究能力扩展到新的环境污染物和环境暴露生物标志物以及新的非法药物及其代谢物的消费生物标志物的基础。该仪器将填补我们将健康/生态风险与未知化学品联系起来的能力方面的一个重要空白，并将使跨学科研究人员能够推进环境毒理学、化学和法医学方面的工作。