Nutrition, Obesity and Atherosclerosis Training Program

营养、肥胖和动脉粥样硬化培训计划

• 批准号: 10553804
• 负责人: Karin E. Bornfeldt
• 金额: $ 35.32万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 1975
• 资助国家: 美国
• 起止时间: 1975-07-01 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10553804
• 关键词: Atherosclerosis; Obesity; Training Programs; nutrition

The Nutrition, Obesity and Atherosclerosis Training Program at the University of Washington is a successful Training Program, now in its 45th year of funding. The overall goal of the program continues to be to provide a highly qualified group of postdoctoral MD physician-scientists and PhD scientists with the research skills they need to become fully independent investigators in the areas of nutrition, obesity and atherosclerosis. The Training Program utilizes 32 investigators at the University of Washington who are performing basic, population science and clinical research in these areas as preceptors. Use is also made of a number of basic and clinical scientists with whom the core faculty collaborates, additional training opportunities provided by our External Advisors, and institutional support to broaden research training and resources available to trainees in the Program. Trainees entering the Program previously have obtained either an MD or PhD degree (or both) and most MD candidates have completed residency training. Some have had some prior research experience. PhD candidates have demonstrated ability in a basic science or population science discipline and have demonstrated capability for research related to the focus of this Program. Selection of the 4 candidates supported by this training grant is made from a large pool of qualified applicants who continue to apply for research training in nutrition, obesity and atherosclerosis at the University of Washington. This Program provides trainees with research experience in basic- population- and clinical science necessary in preparation for independent research careers. Appointments to the Training Program are for at least 2 years, with an optional 3rd year available. The program also includes opportunities for trainees to obtain Master of Public Health or Master of Science degree in the areas of nutritional sciences, epidemiology, global health, and health systems and population health, to interact through program-specific meetings, and to present their research to peers, preceptors, invited scientists from other academic institutions, and at national scientific meetings. A series of didactic lectures, seminars, and journal clubs related to the topics of lipids, obesity, nutrition and atherosclerosis, as well as in scientific methods and biomedical ethics, complement the research training. Rigorous evaluation of trainees and preceptors is performed bi-annually and is overseen by the Internal Advisory Committee and an External Advisory Committee. The Nutrition, Obesity and Atherosclerosis Training Program has been highly successful in training productive scientists, including scientists from underrepresented groups, in these areas during the current funding period, and will provide an even stronger training environment due to several changes to increase diversity, coherence, and training opportunities during the next funding period.

华盛顿大学的营养、肥胖和动脉粥样硬化培训项目取得了成功 培训计划现已进入资助第 45 个年头。该计划的总体目标仍然是提供 高素质的博士后医学博士科学家和博士科学家团队，拥有他们的研究技能 需要成为营养、肥胖和动脉粥样硬化领域完全独立的研究人员。这 培训计划利用了华盛顿大学的 32 名研究人员，他们正在执行基础、 作为这些领域的人口科学和临床研究的导师。还使用了一些基本的 以及与核心教师合作的临床科学家，我们提供的额外培训机会 外部顾问和机构支持，以扩大受训者可用的研究培训和资源 该计划。 之前进入该计划的学员已获得医学博士或博士学位（或两者兼而有之），并且大多数医学博士 候选人已完成住院医师培训。有些人之前有过一些研究经验。博士 候选人已表现出基础科学或人口科学学科的能力，并且具有 展示了与本计划重点相关的研究能力。 4名候选人的遴选 这项培训补助金的支持来自大量合格的申请人，他们继续申请 华盛顿大学营养、肥胖和动脉粥样硬化研究培训。 该计划为学员提供必要的基础人口和临床科学研究经验 为独立研究生涯做准备。培训计划的任命期限至少为 2 年， 可选择第三年。该计划还包括为学员提供获得硕士学位的机会 公共卫生或营养科学、流行病学、全球健康等领域的理学硕士学位 卫生系统和人口健康，通过特定规划的会议进行互动，并展示其 向同行、导师、其他学术机构和国家科学机构邀请的科学家进行研究 会议。一系列与血脂、肥胖、 营养和动脉粥样硬化以及科学方法和生物医学伦理学补充了研究 训练。对学员和导师的严格评估每两年进行一次，并由 内部咨询委员会和外部咨询委员会。 营养、肥胖和动脉粥样硬化培训计划在培训生产力方面取得了巨大成功 在当前资助期间这些领域的科学家，包括来自代表性不足群体的科学家， 由于增加多样性的一些变化，并将提供更强大的培训环境， 下一个资助期间的一致性和培训机会。

项目成果

Aging Increases Susceptibility to Develop Cardiac Hypertrophy following High Sugar Consumption.

• DOI: 10.3390/nu14214645
• 发表时间: 2022-11-03
• 期刊: Nutrients
• 影响因子: 5.9
• 作者: Valencia AP;Whitson JA;Wang S;Nguyen L;den Hartigh LJ;Rabinovitch PS;Marcinek DJ
• 通讯作者: Marcinek DJ

Long-term parenteral nutrition in unrestrained nonhuman primates: an experimental model.

无限制的非人类灵长类动物的长期肠外营养：实验模型。

• DOI: 10.1093/ajcn/51.3.470
• 发表时间: 1990
• 期刊: The American journal of clinical nutrition
• 作者: Friday,KE;Lipkin,EW
• 通讯作者: Lipkin,EW

ApoE enhances lipid uptake by macrophages in lipoprotein lipase deficiency during pregnancy.

ApoE 增强妊娠期间脂蛋白脂肪酶缺乏症的巨噬细胞对脂质的摄取。

• 发表时间: 1996
• 期刊: Journal of lipid research
• 影响因子: 6.5
• 作者: Steinberg,FM;Tsai,EC;Brunzell,JD;Chait,A
• 通讯作者: Chait,A

An unusual manifestation of olfactory neuroblastoma.

嗅神经母细胞瘤的异常表现。

• DOI: 10.1136/bcr-2017-221661
• 发表时间: 2018
• 期刊: BMJ case reports
• 影响因子: 0.9
• 作者: Batacchi,Zona;Andeen,NicoleK;Trikudanathan,Subbulaxmi
• 通讯作者: Trikudanathan,Subbulaxmi

Deletion of FUNDC2 and CMC4 on Chromosome Xq28 Is Sufficient to Cause Hypergonadotropic Hypogonadism in Men.

• DOI: 10.3389/fgene.2020.557341
• 发表时间: 2020
• 期刊: Frontiers in genetics
• 影响因子: 3.7
• 作者: Deng X;Fang H;Pathak A;Zou AM;Neufeld-Kaiser W;Malouf EA;Failor RA;Hisama FM;Liu YJ
• 通讯作者: Liu YJ