Career Enhancement Program

项目摘要/摘要(职业发展方案) 局部分子靶向放射增敏的职业促进计划 密歇根大学的晚期癌症孢子寻求识别和培养一名训练有素、敬业的 研究人员集中在分子靶向放射增敏的研究上。翻译基础知识 临床实践的发现仍然是实施许多有希望的计划的主要挑战 融资机制。因此，我们的计划努力确定和指导不同的科学家群体 致力于参与这一挑战。我们坚信，翻译研究的进展是 依赖于支持和促进调查员的早期职业发展 癌症患者生活的不同之处。CEP确定了那些表现出色的早期职业调查人员 在实现独立方面取得进展，以及对过渡感兴趣的知名调查人员 他们的研究计划将辐射癌症生物学转化为患者护理，以及高级研究人员 具有癌症研究经验，希望在翻译科学方面发展更多专业知识。 后者的例子是基础科学研究人员，他们计划首先测试他们研究的翻译 临床前试验，然后是临床试验。同样，进行临床试验的临床医生计划 开发以实验室为基础的新方法，但他们没有基础科学专业知识或 进行必要的临床前研究和相关研究的实验室也被考虑。高度优先的 CEP将确定、支持和指导传统上在学术上代表性不足的团体的成员 健康科学。孢子将采用基于证据的做法来鼓励教职员工的提案。 他们是传统上代表人数不足的群体的成员，包括妇女和来自 代表种族和民族群体，以及其他群体。此外，孢子还会发展出 将有助于确定和鼓励传统上在学术界代表性较低的团体提出的建议 来自附近为少数族裔人口服务的机构的健康科学。孢子领导力和 调查人员将鼓励最佳做法，以确保成功的指导和职业发展 参与者。指导团队将包括经验丰富的导师，他们也将获得正式的 在指导和赞助两方面进行培训。该计划将阐明以下方面的明确期望和目标 职业发展和指导关系。它将支持参与者在以下领域的专业发展 临床试验设计和拨款撰写等领域；它还将提供现实世界中磨练的机会 在孢子年度务虚会上的展示和网络技巧。CEP课程将针对以下技能 谈判、工作与生活融合和领导力发展等领域，鼓励在 除了在该计划中建立的其他形式的指导之外。将仔细衡量影响 并进行了评估。

PROJECT SUMMARY/ABSTRACT (CAREER ENHANCEMENT PROGRAM) The Career Enhancement Program (CEP) of the Molecularly Targeted Radiosensitization of Locally Advanced Cancers SPORE at the University of Michigan seeks to identify and foster a trained and engaged pool of investigators focused on studies of molecularly targeted radiosensitization. Translating basic discoveries into clinical practice remains a major challenge to the implementation of many promising funding mechanisms. Accordingly, our program strives to identify and mentor a diverse group of scientists committed to engaging in this challenge. We firmly believe that progress in translational research is dependent on supporting and enhancing early career development of investigators committed to make a difference in cancer patients’ lives. The CEP identifies early career investigators who demonstrate excellent progress towards achieving independence, as well as established investigators interested in transitioning their research program to translation of radiation cancer biology to patient care, and senior investigators with cancer research experience who desire to develop additional expertise in translational science. Examples of the latter are basic science investigators who plan to test the translation of their studies first in pre-clinical testing followed by clinical trials. Similarly, clinicians conducting clinical trials who plan to develop novel approaches grounded in the laboratory but who do not have basic science expertise or a wet lab in which to conduct necessary preclinical and correlative studies are also considered. A high priority of the CEP is to identify, support and mentor members of groups traditionally under-represented in academic health sciences. The SPORE will employ evidence-based practices to encourage proposals from faculty who are members of groups traditionally under-represented, including women and those from under- represented racial and ethnic groups, among others. In addition, the SPORE will develop relationships that will enable identification and encourage proposals from groups traditionally underrepresented in academic health sciences from nearby institutions that serve minority populations. SPORE leadership and investigators will encourage best practices to ensure successful mentorship and career development of participants. Mentoring teams will include experienced mentors who will also be provided with formal training in both mentorship and sponsorship. The program will articulate clear expectations and goals for career development and mentoring relationships. It will support participants’ professional development in areas like clinical trial design and grant writing; it will also offer real-world opportunities for honing presentation and networking skills in the SPORE annual retreats. The CEP curriculum will target skills in areas like negotiation, work-life integration, and leadership development, encouraging peer mentorship in addition to the other forms of mentorship established in the program. Impact will be carefully measured and evaluated.