Career Enhancement Program

职业提升计划

• 批准号: 10554480
• 负责人: MATS LJUNGMAN
• 金额: $ 9.57万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-08-14 至 2028-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10554480
• 关键词: Applications Grants; Area; Articulation; Basic Science; Cancer Biology; Cancer Patient; Clinical Trials; Clinical Trials Design; Conduct Clinical Trials; Correlative Study; Development; Early identification; Educational Curriculum; Ensure; Ethnic Population; Evidence based practice; Faculty; Fostering; Funding Mechanisms; Goals; Grant; Health Sciences; Individual; Laboratories; Leadership; Life; Locally Advanced Malignant Neoplasm; Manuscripts; Measures; Mediation; Mentors; Mentorship; Michigan; Minority Groups; Minority-Serving Institution; Molecular Target; Monitor; Participant; Patient Care; Peer Review; Preclinical Testing; Qualifying; Radiation; Radiobiology; Radiosensitization; Reporting; Research; Research Infrastructure; Research Personnel; Research Project Grants; Resources; Scientist; Testing; Training; Training Support; Translating; Translational Research; Translations; Universities; Woman; Work; Writing; anticancer research; career; career development; clinical practice; expectation; experience; health equity; interest; leadership development; member; novel; novel strategies; peer; preclinical study; programs; racial population; senior faculty; skills; success; support network; translational potential; translational scientist

PROJECT SUMMARY/ABSTRACT (CAREER ENHANCEMENT PROGRAM) The Career Enhancement Program (CEP) of the Molecularly Targeted Radiosensitization of Locally Advanced Cancers SPORE at the University of Michigan seeks to identify and foster a trained and engaged pool of investigators focused on studies of molecularly targeted radiosensitization. Translating basic discoveries into clinical practice remains a major challenge to the implementation of many promising funding mechanisms. Accordingly, our program strives to identify and mentor a diverse group of scientists committed to engaging in this challenge. We firmly believe that progress in translational research is dependent on supporting and enhancing early career development of investigators committed to make a difference in cancer patients’ lives. The CEP identifies early career investigators who demonstrate excellent progress towards achieving independence, as well as established investigators interested in transitioning their research program to translation of radiation cancer biology to patient care, and senior investigators with cancer research experience who desire to develop additional expertise in translational science. Examples of the latter are basic science investigators who plan to test the translation of their studies first in pre-clinical testing followed by clinical trials. Similarly, clinicians conducting clinical trials who plan to develop novel approaches grounded in the laboratory but who do not have basic science expertise or a wet lab in which to conduct necessary preclinical and correlative studies are also considered. A high priority of the CEP is to identify, support and mentor members of groups traditionally under-represented in academic health sciences. The SPORE will employ evidence-based practices to encourage proposals from faculty who are members of groups traditionally under-represented, including women and those from under- represented racial and ethnic groups, among others. In addition, the SPORE will develop relationships that will enable identification and encourage proposals from groups traditionally underrepresented in academic health sciences from nearby institutions that serve minority populations. SPORE leadership and investigators will encourage best practices to ensure successful mentorship and career development of participants. Mentoring teams will include experienced mentors who will also be provided with formal training in both mentorship and sponsorship. The program will articulate clear expectations and goals for career development and mentoring relationships. It will support participants’ professional development in areas like clinical trial design and grant writing; it will also offer real-world opportunities for honing presentation and networking skills in the SPORE annual retreats. The CEP curriculum will target skills in areas like negotiation, work-life integration, and leadership development, encouraging peer mentorship in addition to the other forms of mentorship established in the program. Impact will be carefully measured and evaluated.

项目概要/摘要（职业发展计划） 分子靶向局部放射增敏的职业提升计划（CEP） 密歇根大学的先进癌症孢子旨在识别和培养一个训练有素和参与 集中研究分子靶向放射增敏作用的研究人员。翻译基础 临床实践中的发现仍然是实施许多有希望的 供资机制。因此，我们的计划致力于确定和指导不同的科学家群体 致力于应对这一挑战。我们坚信，转化研究的进展是 依赖于支持和加强致力于使调查员的职业生涯更有意义的早期发展， 癌症患者的生活差异。CEP确定了表现出色的早期职业调查员 在实现独立性方面取得的进展，以及对过渡感兴趣的常设调查员 他们的研究计划，以翻译放射癌症生物学的病人护理，和高级研究人员 具有癌症研究经验，希望在转化科学方面发展更多专业知识的人。 后者的例子是基础科学研究人员，他们计划首先测试他们研究的翻译， 临床前测试，然后是临床试验。同样，进行临床试验的临床医生计划 在实验室中开发新的方法，但他们没有基本的科学专业知识或湿 还考虑了进行必要的临床前和相关研究的实验室。的一个高度优先事项 CEP的目的是识别、支持和指导传统上在学术领域代表性不足的群体的成员， 健康科学SPORE将采用基于证据的做法，鼓励教师提出建议 传统上代表性不足的群体的成员，包括妇女和代表性不足的群体， 代表种族和族裔群体等。此外，SPORE将发展关系， 将能够识别并鼓励传统上在学术界代表性不足的群体提出建议。 为少数民族服务的附近机构的健康科学。SPORE领导力和 调查人员将鼓励最佳做法，以确保成功的指导和职业发展， 参与者指导团队将包括经验丰富的指导者，他们还将获得正式的 指导和赞助方面的培训。该计划将阐明明确的期望和目标， 职业发展和指导关系。它将支持参与者的专业发展， 临床试验设计和赠款写作等领域;它还将提供现实世界的磨练机会 在SPORE年度务虚会中的演讲和网络技能。CEP课程将针对以下技能： 在谈判、工作与生活融合和领导力发展等领域，鼓励在 除了在该计划中建立的其他形式的导师。将仔细衡量影响 和评价