Training in Advanced Heart Disease Research

锡达斯-西奈医学中心(CSMC)史密特心脏研究所(SHI)正在申请第二届 更新其博士后高级心脏病研究培训计划。这个项目的目标是 是在基础生物医学、翻译或健康服务方面提供出色的团队指导培训 对6名博士后研究员进行研究(每年3次×2年)。我们的目标是为学员提供必要的 在心血管科学领域发展独立而富有成效的学术生涯的技能。我们试图确保 我们所有的实习生，无论是博士、医学博士、医学博士或同等学历的人，都能深入了解 心血管医学中临床相关问题的科学基础，以及全面的 了解严谨的研究设计、适当的方法和专业的基础和技术执行 临床研究。这不仅为临床研究人员提供了正确检验假说所需的技能 在基础科学水平上产生，但也向基础科学家提供关于疾病的临床方面的信息 以促进实验室中与临床相关的最先进的研究。我们的培训计划的领域 研究重点包括心脏生物学、心律失常、血管生物学和动脉粥样硬化、再生 医学、移植免疫学、心血管成像、妇女健康、社区健康、 实施科学、精密医学、人工智能、蛋白质组学和遗传学。培训 该计划充分利用了华西最大的私立教学医院CSMC的独特优势 密西西比州，长期致力于翻译研究和服务于当地社区。 史氏心脏移植是世界上最大的成人心脏移植项目，由美国国立卫生研究院资助，是第一个人类心脏移植项目 心脏干细胞疗法的试验，并吸引了许多NIH资助的基础和翻译 调查人员。其中一些人在CSMC的其他单位共享联合任命，其中包括再生部 医学研究所、生物医学成像研究所、高级临床生物系统研究所和 生物医学科学系、医学系和病理学系。学员们接受了深入的研究 在重点调查领域的经验，加上正规课程，包括基础和 临床研讨会、补助金和手稿写作指导、生物统计学、方法论和伦理学。课程有 由生物医学科学系、CSMC临床学者计划和一个多校区提供 NIH CTSA支持的翻译科学研究所中心(CTSI，包括CSMC、UCLA、Harbor-UCLA、 和查尔斯·R·德鲁大学)。CTSI为我们的学员提供了获得项目种子资金的特权， 临床研究设计、方法学和生物统计学的附加课程，加州大学洛杉矶分校公开学位课程 健康和临床研究，以及进行从工作台到床边到 社区。总而言之，我们设计了一个计划，在以下关键领域提供深入培训 在倡导转化性研究和临床卓越的环境中开展心血管科学。

The Smidt Heart Institute (SHI) at Cedars-Sinai Medical Center (CSMC) is applying for the second competitive renewal of its postdoctoral Advanced Heart Disease Research Training Program. The objective of this program is to provide outstanding team-mentored training in either basic biomedical, translational or health services research to six postdoctoral fellows (3 per year x 2 years). The goal is to provide trainees with the necessary skills to develop independent and productive academic careers in cardiovascular science. We seek to ensure that all our trainees, be they PhDs, MDs, MD/PhDs or equivalent, develop an in-depth knowledge of the basic science underpinning clinically relevant problems in cardiovascular medicine, as well as a comprehensive understanding of rigorous study design, appropriate methodology, and expert technical execution of basic and clinical studies. This not only provides clinical investigators with the skills they need to properly test hypotheses generated at the basic science level, but also informs basic scientists about the clinical aspects of disease in order to stimulate clinically relevant state-of-the-art investigations in the laboratory. Our training program’s areas of research focus include Cardiac Biology, Arrhythmias, Vascular Biology and Atherosclerosis, Regenerative Medicine, Transplant Immunology, Cardiovascular Imaging, Women’s Health, Community Health, Implementation Science, Precision Medicine, Artificial Intelligence, Proteomics, and Genetics. The Training Program takes full advantage of the unique strengths of CSMC, the largest private teaching hospital west of the Mississippi, which has a longstanding commitment to translational research and to serving the local community. The SHI houses the largest adult heart transplant program in the world, performed an NIH-funded first-in-human trial of cardiac-derived stem cell therapy, and has attracted many NIH-funded basic and translational investigators. Some of these share joint appointments in other CSMC units, which include the Regenerative Medicine Institute, Biomedical Imaging Research Institute, Advanced Clinical Biosystems Institute and the Departments of Biomedical Sciences, Medicine, and Pathology. Trainees receive an intensive research experience in a focused area of investigation, augmented by a formal curriculum that includes both basic and clinical seminars, instruction in grant and manuscript writing, biostatistics, methodology, and ethics. Courses are provided by the Department of Biomedical Sciences, the CSMC Clinical Scholars Program, and a multi-campus NIH CTSA-supported Center for Translational Science Institute (CTSI, includes CSMC, UCLA, Harbor-UCLA, and Charles R. Drew University). The CTSI provides our trainees with privileged access to project seed funds, additional courses in clinical research design, methodology and biostatistics, UCLA degree programs in public health and clinical research, and tools for conducting the entire range of studies from bench to bedside to community. In summary, we have designed a program that provides in-depth training in critical areas of cardiovascular science within an environment that champions translational research and clinical excellence.