Training in Advanced Heart Disease Research
高级心脏病研究培训
基本信息
- 批准号:10556039
- 负责人:
- 金额:$ 54.02万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2013
- 资助国家:美国
- 起止时间:2013-08-01 至 2028-07-31
- 项目状态:未结题
- 来源:
- 关键词:
项目摘要
The Smidt Heart Institute (SHI) at Cedars-Sinai Medical Center (CSMC) is applying for the second competitive
renewal of its postdoctoral Advanced Heart Disease Research Training Program. The objective of this program
is to provide outstanding team-mentored training in either basic biomedical, translational or health services
research to six postdoctoral fellows (3 per year x 2 years). The goal is to provide trainees with the necessary
skills to develop independent and productive academic careers in cardiovascular science. We seek to ensure
that all our trainees, be they PhDs, MDs, MD/PhDs or equivalent, develop an in-depth knowledge of the basic
science underpinning clinically relevant problems in cardiovascular medicine, as well as a comprehensive
understanding of rigorous study design, appropriate methodology, and expert technical execution of basic and
clinical studies. This not only provides clinical investigators with the skills they need to properly test hypotheses
generated at the basic science level, but also informs basic scientists about the clinical aspects of disease in
order to stimulate clinically relevant state-of-the-art investigations in the laboratory. Our training program’s areas
of research focus include Cardiac Biology, Arrhythmias, Vascular Biology and Atherosclerosis, Regenerative
Medicine, Transplant Immunology, Cardiovascular Imaging, Women’s Health, Community Health,
Implementation Science, Precision Medicine, Artificial Intelligence, Proteomics, and Genetics. The Training
Program takes full advantage of the unique strengths of CSMC, the largest private teaching hospital west of the
Mississippi, which has a longstanding commitment to translational research and to serving the local community.
The SHI houses the largest adult heart transplant program in the world, performed an NIH-funded first-in-human
trial of cardiac-derived stem cell therapy, and has attracted many NIH-funded basic and translational
investigators. Some of these share joint appointments in other CSMC units, which include the Regenerative
Medicine Institute, Biomedical Imaging Research Institute, Advanced Clinical Biosystems Institute and the
Departments of Biomedical Sciences, Medicine, and Pathology. Trainees receive an intensive research
experience in a focused area of investigation, augmented by a formal curriculum that includes both basic and
clinical seminars, instruction in grant and manuscript writing, biostatistics, methodology, and ethics. Courses are
provided by the Department of Biomedical Sciences, the CSMC Clinical Scholars Program, and a multi-campus
NIH CTSA-supported Center for Translational Science Institute (CTSI, includes CSMC, UCLA, Harbor-UCLA,
and Charles R. Drew University). The CTSI provides our trainees with privileged access to project seed funds,
additional courses in clinical research design, methodology and biostatistics, UCLA degree programs in public
health and clinical research, and tools for conducting the entire range of studies from bench to bedside to
community. In summary, we have designed a program that provides in-depth training in critical areas of
cardiovascular science within an environment that champions translational research and clinical excellence.
Cedars-Sinai医学中心(CSMC)的心脏研究所(SHI)正在申请第二次竞争性
更新其博士后高级心脏病研究培训计划。该计划的目标
在基础生物医学、翻译或健康服务方面提供出色的团队指导培训
为6名博士后研究员提供研究(每年3名x2年)。目标是为学员提供必要的
培养心血管科学独立和富有成效的学术生涯的技能。我们寻求确保
我们所有的学员,无论是博士,医学博士,医学博士/博士或同等学历,都要深入了解基本的
心血管医学临床相关问题的科学基础,以及一个全面的
了解严格的研究设计,适当的方法学,以及基本和
临床研究。这不仅为临床研究者提供了正确检验假设所需的技能
在基础科学水平上产生,但也告知基础科学家关于疾病的临床方面,
以刺激实验室中临床相关的最新研究。我们的培训项目
研究方向包括心脏生物学、心律失常、血管生物学和动脉粥样硬化、再生
医学,移植免疫学,心血管成像,妇女健康,社区健康,
实施科学、精准医学、人工智能、蛋白质组学和遗传学。培训
该计划充分利用了CSMC的独特优势,CSMC是美国西部最大的私立教学医院。
密西西比,它有一个长期致力于转化研究和服务当地社区。
SHI拥有世界上最大的成人心脏移植计划,进行了NIH资助的首次人体心脏移植。
心脏源性干细胞治疗的试验,并吸引了许多NIH资助的基础和转化
investigators.其中一些人在其他CSMC单位共享联合任命,其中包括再生
医学研究所、生物医学成像研究所、高级临床生物系统研究所和
生物医学科学、医学和病理学系。学员接受密集的研究
在调查的重点领域的经验,通过正式的课程,包括基础和补充,
临床研讨会,指导赠款和手稿写作,生物统计学,方法学和伦理学。课程
由生物医学科学系,CSMC临床学者计划和多校区提供
NIH CTSA支持的转化科学研究中心(CTSI,包括CSMC,UCLA,Harbor-UCLA,
查尔斯·R。德鲁大学)。CTSI为我们的学员提供获得项目种子基金的特权,
在临床研究设计,方法学和生物统计学,加州大学洛杉矶分校学位课程在公共附加课程
健康和临床研究,以及用于进行从实验台到床边的整个研究范围的工具,
社区总之,我们设计了一个计划,在关键领域提供深入的培训,
心血管科学在一个环境中,冠军转化研究和临床卓越。
项目成果
期刊论文数量(57)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Refining Safe Contrast Limits for Preventing Acute Kidney Injury After Percutaneous Coronary Intervention.
- DOI:10.1161/jaha.120.018890
- 发表时间:2021-01-05
- 期刊:
- 影响因子:5.4
- 作者:Yuan N;Latif K;Botting PG;Elad Y;Bradley SM;Nuckols TK;Cheng S;Ebinger JE
- 通讯作者:Ebinger JE
Evaluating age-based eligibility thresholds for heart re-transplantation - an analysis of the united network for organ sharing database.
评估基于年龄的心脏再移植资格阈值——对器官共享数据库联合网络的分析。
- DOI:10.1016/j.healun.2022.11.012
- 发表时间:2023
- 期刊:
- 影响因子:0
- 作者:Chen,Qiudong;Malas,Jad;Chan,Joshua;Esmailian,Gabriel;Emerson,Dominic;Megna,Dominick;Catarino,Pedro;Bowdish,MichaelE;Kittleson,Michelle;Patel,Jignesh;Chikwe,Joanna;Kobashigawa,Jon;Esmailian,Fardad
- 通讯作者:Esmailian,Fardad
Allogeneic cardiospheres delivered via percutaneous transendocardial injection increase viable myocardium, decrease scar size, and attenuate cardiac dilatation in porcine ischemic cardiomyopathy.
- DOI:10.1371/journal.pone.0113805
- 发表时间:2014
- 期刊:
- 影响因子:3.7
- 作者:Yee K;Malliaras K;Kanazawa H;Tseliou E;Cheng K;Luthringer DJ;Ho CS;Takayama K;Minamino N;Dawkins JF;Chowdhury S;Duong DT;Seinfeld J;Middleton RC;Dharmakumar R;Li D;Marbán L;Makkar RR;Marbán E
- 通讯作者:Marbán E
Impact of minimally invasive lung transplantation on early outcomes and analgesia use: A matched cohort study.
微创肺移植对早期结果和镇痛使用的影响:一项匹配队列研究。
- DOI:10.1016/j.healun.2024.01.014
- 发表时间:2024
- 期刊:
- 影响因子:0
- 作者:Thomas,Jason;Chen,Qiudong;Malas,Jad;Barnes,Darina;Roach,Amy;Peiris,Achille;Premananthan,Sharmini;Krishnan,Aasha;Rowe,Georgina;Gill,George;Zaffiri,Lorenzo;Chikwe,Joanna;Emerson,Dominic;Catarino,Pedro;Rampolla,Reinaldo;Megna,D
- 通讯作者:Megna,D
Heart transplantation using donation after circulatory death in the United States.
在美国,循环死亡后使用捐赠进行心脏移植。
- DOI:10.1016/j.jtcvs.2022.05.005
- 发表时间:2023
- 期刊:
- 影响因子:0
- 作者:Chen,Qiudong;Emerson,Dominic;Megna,Dominick;Osho,Asishana;Roach,Amy;Chan,Joshua;Rowe,Georgina;Gill,George;Esmailian,Fardad;Chikwe,Joanna;Egorova,Natalia;Kirklin,JamesK;Kobashigawa,Jon;Catarino,Pedro
- 通讯作者:Catarino,Pedro
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Joshua I Goldhaber其他文献
Joshua I Goldhaber的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Joshua I Goldhaber', 18)}}的其他基金
Cardiac Myocyte Protein Partners in Heart Function
心肌细胞蛋白在心脏功能中的伙伴
- 批准号:
10502152 - 财政年份:2022
- 资助金额:
$ 54.02万 - 项目类别:
Cardiac Myocyte Protein Partners in Heart Function
心肌细胞蛋白在心脏功能中的伙伴
- 批准号:
10667626 - 财政年份:2022
- 资助金额:
$ 54.02万 - 项目类别:
Regulation of cellular calcium by cardiac sodium-calcium exchange
通过心脏钠钙交换调节细胞钙
- 批准号:
9906764 - 财政年份:2019
- 资助金额:
$ 54.02万 - 项目类别:
Regulation of cellular calcium by cardiac sodium-calcium exchange
通过心脏钠钙交换调节细胞钙
- 批准号:
10376807 - 财政年份:2019
- 资助金额:
$ 54.02万 - 项目类别:
Regulation of cellular calcium by cardiac sodium-calcium exchange
通过心脏钠钙交换调节细胞钙
- 批准号:
9766112 - 财政年份:2019
- 资助金额:
$ 54.02万 - 项目类别:
相似国自然基金
Research on Quantum Field Theory without a Lagrangian Description
- 批准号:24ZR1403900
- 批准年份:2024
- 资助金额:0.0 万元
- 项目类别:省市级项目
Cell Research
- 批准号:31224802
- 批准年份:2012
- 资助金额:24.0 万元
- 项目类别:专项基金项目
Cell Research
- 批准号:31024804
- 批准年份:2010
- 资助金额:24.0 万元
- 项目类别:专项基金项目
Cell Research (细胞研究)
- 批准号:30824808
- 批准年份:2008
- 资助金额:24.0 万元
- 项目类别:专项基金项目
Research on the Rapid Growth Mechanism of KDP Crystal
- 批准号:10774081
- 批准年份:2007
- 资助金额:45.0 万元
- 项目类别:面上项目
相似海外基金
TARGET Mineral Resources - Training And Research Group for Energy Transition Mineral Resources
TARGET 矿产资源 - 能源转型矿产资源培训与研究小组
- 批准号:
NE/Y005457/1 - 财政年份:2024
- 资助金额:
$ 54.02万 - 项目类别:
Training Grant
Collaborative Research: CyberTraining: Pilot: PowerCyber: Computational Training for Power Engineering Researchers
协作研究:CyberTraining:试点:PowerCyber:电力工程研究人员的计算培训
- 批准号:
2319895 - 财政年份:2024
- 资助金额:
$ 54.02万 - 项目类别:
Standard Grant
Collaborative Research: CyberTraining: Implementation: Medium: Training Users, Developers, and Instructors at the Chemistry/Physics/Materials Science Interface
协作研究:网络培训:实施:媒介:在化学/物理/材料科学界面培训用户、开发人员和讲师
- 批准号:
2321102 - 财政年份:2024
- 资助金额:
$ 54.02万 - 项目类别:
Standard Grant
Project Incubation: Training Undergraduates in Collaborative Research Ethics
项目孵化:培养本科生合作研究伦理
- 批准号:
2316154 - 财政年份:2024
- 资助金额:
$ 54.02万 - 项目类别:
Standard Grant
REU Site: ASL-English Bilingual Cognitive and Educational Neuroscience Training and Research Experience (ASL-English Bilingual CENTRE)
REU网站:ASL-英语双语认知和教育神经科学培训和研究经验(ASL-英语双语中心)
- 批准号:
2349454 - 财政年份:2024
- 资助金额:
$ 54.02万 - 项目类别:
Standard Grant
Travel: Support for U.S. Students to Receive Training on Research Cyberinfrastructure at the 2024 Annual Modeling and Simulation Conference (ANNSIM)
旅行:支持美国学生在 2024 年年度建模与仿真会议 (ANNSIM) 上接受研究网络基础设施培训
- 批准号:
2425778 - 财政年份:2024
- 资助金额:
$ 54.02万 - 项目类别:
Standard Grant
Collaborative Research: CyberTraining: Implementation: Medium: Training Users, Developers, and Instructors at the Chemistry/Physics/Materials Science Interface
协作研究:网络培训:实施:媒介:在化学/物理/材料科学界面培训用户、开发人员和讲师
- 批准号:
2321103 - 财政年份:2024
- 资助金额:
$ 54.02万 - 项目类别:
Standard Grant
Broadening Participation, Fostering Cultural Wealth, and Increasing Student Success Through an Undergraduate Research Training Program
通过本科生研究培训计划扩大参与、培育文化财富并提高学生的成功
- 批准号:
2345290 - 财政年份:2024
- 资助金额:
$ 54.02万 - 项目类别:
Standard Grant
Collaborative Research: CyberTraining: Pilot: PowerCyber: Computational Training for Power Engineering Researchers
协作研究:CyberTraining:试点:PowerCyber:电力工程研究人员的计算培训
- 批准号:
2319896 - 财政年份:2024
- 资助金额:
$ 54.02万 - 项目类别:
Standard Grant
REU Site: Interdisciplinary Training for Research and Outreach in Climate Science (IT-ROCS)
REU 网站:气候科学研究和推广跨学科培训 (IT-ROCS)
- 批准号:
2243657 - 财政年份:2024
- 资助金额:
$ 54.02万 - 项目类别:
Standard Grant