Scientific Leadership Group Core

科学领导小组核心

• 批准号: 10595900
• 负责人: Lisa B Hightow-Weidman
• 金额: $ 425.15万
• 依托单位: FLORIDA STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-01-25 至 2029-11-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10595900
• 关键词: Accountability; Acquired Immunodeficiency Syndrome; Address; Adolescent; Adolescent Medicine Trials Network; Adolescent and Young Adult; Area; Articulation; Bioethics; Caring; Clinical; Clinical Investigator; Clinical Protocols; Clinical Trials; Cognitive; Collaborations; Communication; Community Practice; Development; Discipline; Dissemination and Implementation; Effectiveness; Emotional; Ensure; Epidemic; Equity; Fostering; Funding; Future; Gender Identity; Geography; Goals; HIV; HIV-infected adolescents; HIV/AIDS; Infrastructure; Institution; Interdisciplinary Study; Intervention; Intervention Studies; Intervention Trial; Investments; Knowledge; Leadership; Mentors; Mission; Outcome; Policies; Positioning Attribute; Practice Guidelines; Prevention; Prevention strategy; Problem Solving; Public Health; Publications; Qualifying; Research; Research Activity; Research Personnel; Research Priority; Research Project Grants; Resource-limited setting; Risk; Role; Science; Site; Therapeutic; Training; Translating; Translations; Underrepresented Minority; United States; United States National Institutes of Health; Youth; adolescent HIV prevention; clinical development; clinical practice; co-infection; comorbidity; data management; design; diagnostic technologies; ethnic identity; experience; flexibility; health equity; industry partner; innovation; laboratory equipment; lens; member; mobile computing; multidisciplinary; next generation; operation; policy recommendation; racial identity; resilience; response; sexual identity; social; synergism; therapy design; working group

PROJECT SUMMARY The Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN) fills a unique role among the NIH- funded networks by bringing together scientific and clinical investigators with the requisite knowledge and experience to design and implement interdisciplinary, developmentally appropriate prevention strategies for youth living with HIV and those at-risk in the United States (US). An experienced, multidisciplinary, and visionary Scientific Leadership Group (SLG) is needed who is poised to develop, refine, and support both an established and emerging ATN scientific agenda that impacts the HIV epidemic among youth domestically. Seamless collaboration will be essential at all levels, expecting and requiring innovation from investigators invested in addressing the significant challenges and seizing opportunities within the field of adolescent HIV prevention and care research. Efficient and effective communication strategies to accomplish high-impact research obligates synergies between the ATN SLG and Scientific Leadership Center (SLC), the Statistical and Data Management Core (SDMC), the Operations and Collaborations Center (OCC), the Research Project teams, Site Consortiums and NIH and industry partners. The SLG, working collaboratively with the SLC, SDMC, OCC and NIH is poised to actuate the unique mission, strengths, and expertise housed within the ATN, to identify gaps in the ATN research portfolio, and to form additional strategic partnerships that ensure the ATN’s swift response to high priority and emergent research areas. Given the broad ATN agenda, we have formulated a strong, interdisciplinary SLG which includes the world’s experts in all areas relevant to ending the HIV epidemic among adolescents in the US. This team consists of investigators with diverse expertise and experiences, including diversity in terms of race/ethnicity, sexual and gender identity, HIV-status, geography, discipline, and training. Building upon years of collective experience, Drs. Hightow-Weidman and Hosek will provide the necessary leadership and infrastructure to support the SLG to develop and refine the research agenda of the ATN, convene working groups as needed, prioritize emerging research projects, efficiently manage the development of clinical protocols, implement, and complete clinical trials and ensure timely publication and communication of results. Drs. Hightow-Weidman and Hosek aim to use an approach toward management of the SLG, honed through decades of prior ATN and clinical trials experiences, that will foster innovation and effectiveness through flexibility, open communication between all SLG team members, mutual respect, collective problem solving, and shared accountability. The SLG is configured through Leadership Teams organized around six areas: Biomedical Therapeutics, Comorbidities and Coinfections, Laboratory, Diagnostics and Mobile Technologies, Institutions, Organizations and Policy, Equity, Inclusion, and Engagement, and Risk and Resilience, and supported by a Bioethics Committee. These content areas encompass the areas of focus required to truly catalyze multidisciplinary research and translate the findings to ensure maximum clinical and policy impact by the ATN.

项目摘要 艾滋病毒/艾滋病干预青少年医学试验网络（ATN）在NIH中发挥着独特的作用， 通过将具有必要知识的科学和临床研究人员聚集在一起， 设计和执行适合发展的跨学科预防战略的经验， 美国艾滋病毒感染者和高危青年。一个经验丰富，多学科，有远见的 科学领导小组（SLG）是需要谁是准备发展，完善，并支持这两个既定的 和正在出现的ATN科学议程，影响国内青年中的艾滋病毒流行。无缝 在各个层面的合作都是必不可少的，期待并要求投资于 在预防青少年艾滋病毒领域应对重大挑战并抓住机遇， 护理研究。高效和有效的沟通策略，以完成高影响力的研究义务 ATN SLG和科学领导中心（SLC）之间的协同作用，统计和数据管理 核心（SDMC）、运营和协作中心（OCC）、研究项目团队、研究中心联盟 以及国家卫生研究院和行业合作伙伴。SLG与SLC、SDMC、OCC和NIH合作， 激活ATN的独特使命、优势和专业知识，识别ATN的差距 研究组合，并形成额外的战略伙伴关系，以确保ATN的快速反应，高 优先和紧急研究领域。鉴于ATN的广泛议程，我们制定了一个强大的， 跨学科的SLG，其中包括世界各地的专家在所有有关领域结束艾滋病毒的流行， 美国的青少年。该团队由具有不同专业知识和经验的调查人员组成，包括 在种族/民族、性和性别认同、艾滋病毒状况、地理、纪律和培训方面的多样性。 基于多年的集体经验，Hightow-Weidman和Hosek博士将提供必要的 领导和基础设施，以支持SLG制定和完善ATN的研究议程，召集 工作组根据需要，优先考虑新兴的研究项目，有效地管理临床开发 方案，实施和完成临床试验，并确保及时公布和交流结果。 Drs. Hightow-Weidman和Hosek的目标是使用一种管理SLG的方法， 数十年的ATN和临床试验经验，将通过以下方式促进创新和有效性： 灵活性，所有SLG团队成员之间的开放式沟通，相互尊重，集体解决问题， 分担责任。SLG通过围绕六个领域组织的领导团队进行配置：生物医学 治疗，合并症和合并感染，实验室，诊断和移动的技术，机构， 组织和政策，公平，包容和参与，风险和弹性，并得到支持， 生物伦理委员会。这些内容领域涵盖了真正促进 多学科研究和翻译的结果，以确保最大的临床和政策的影响，由ATN。