Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN) Scientific Leadership Center
艾滋病毒/艾滋病干预青少年医学试验网络 (ATN) 科学领导中心
基本信息
- 批准号:10595899
- 负责人:
- 金额:$ 1116.21万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2023
- 资助国家:美国
- 起止时间:2023-01-25 至 2029-11-30
- 项目状态:未结题
- 来源:
- 关键词:AIDS preventionAchievementAcquired Immunodeficiency SyndromeAddressAdolescenceAdolescentAdolescent Medicine Trials NetworkAdolescent and Young AdultAgeAreaCaringClinical ResearchClinical TrialsCollaborationsCommunicationCommunitiesComplexContinuity of Patient CareDevelopmentElementsEmotionalEnsureEpidemicEvolutionFriendsGoalsGrowthHIVHIV InfectionsHIV SeronegativityHIV/AIDSHIV/STDIndividualInfectionInfrastructureInterventionLeadershipMental HealthMissionNeurocognitiveOilsOwnershipPharmaceutical PreparationsPhasePopulationPovertyPrevalencePreventionProductivityQualifyingResearchResearch PriorityResourcesScienceSocial ChangeStructureSubstance abuse problemSystemTalentsUnited StatesUnited States National Institutes of HealthViolenceViralVisionWorkYouthadolescent HIV preventionadolescent health outcomesage groupcareerclinical research sitecommunity-level factordesignevidence baseexperienceimprovedinnovationinsightmedical appointmentmultidisciplinaryoperationpre-exposure prophylaxisprogramsracismresiliencesocial stigmauptakeyoung adult
项目摘要
Adolescents and young adults (AYA) under the age of 25 in the United States (US) are the least likely of all age
groups to: 1) know their HIV status, 2) initiate PrEP if HIV-negative even when indicated, 3) take medication as
prescribed, attend medical appointments, and be virally suppressed if living with HIV. Persistent rates of new
infections among US youth indicate that evidence-based and integrated approaches to increase the uptake and
use of effective biomedical prevention and treatment products are required. Adolescence and young adulthood
are challenging developmental periods, with significant physical, neurocognitive, emotional, and social changes.
While multiple vulnerabilities and complex community factors drive the HIV epidemic among youth, these
developmental periods are also characterized by opportunities for growth, achievement, and resilience. HIV
research networks must be broad in agenda, go beyond traditional clinical sites and individual level interventions
and address the multi-faceted, multi-level barriers that have thwarted HIV prevention and care progress among
AYA. The newly envisioned Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN) is a multi-
component collaborative research enterprise focused on the reduction of new HIV infections among AYA in the
US as well as improvements across the HIV continuum of care for youth living with HIV. Such a large-scale,
complex clinical research program demands high productivity and strong contributions from each essential
component. Our proposed overall network structure is conceptualized as a well-oiled machine with
interdependent structures working together seamlessly to achieve the mission of the ATN. The Scientific
Leadership Center (SLC) will bring all elements together and ensure that they function collaboratively, effectively,
and efficiently with the Operations and Collaboration Center (OCC), NIH, and the overall network. The ATN has
identified five high priority research areas to address the substantial and disproportionate gaps in the health
outcomes of AYA across the HIV prevention and care continuum. With this application, we include seven highly
innovative and impactful clinical trials led by talented multi-disciplinary teams, addressing all five priority research
areas, spanning key populations of youth, multiple socioecological systems, and a variety of regulatory phases.
We are also poised to accept emerging research opportunities as the field of prevention and treatment science
advances. Communities will be situated at the center of the ATN’s work because community ownership,
engagement, and connectedness are critical for successful research implementation. Drs. Hightow-Weidman
and Hosek are uniquely qualified as MPIs to lead the SLC. Both have worked in the field of adolescent HIV
prevention and treatment for the entirety of their careers and have worked collaboratively within the ATN for >16
years, giving them clear insight on how best to make this new iteration successful. Our overall vision for a
redesigned and robust ATN is one that not only anticipates and plans for ongoing evolution in the HIV field and
an emerging scientific agenda but one with a renewed focus on the most impactful science and priority areas.
在美国,25岁以下的青少年和年轻人(AYA)是所有年龄段中最不可能的
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Lisa B Hightow-Weidman其他文献
Studying the Digital Intervention Engagement–Mediated Relationship Between Intrapersonal Measures and Pre-Exposure Prophylaxis Adherence in Sexual and Gender Minority Youth: Secondary Analysis of a Randomized Controlled Trial
研究数字干预参与度——性少数青年中人际测量与暴露前预防依从性之间的中介关系:一项随机对照试验的二次分析
- DOI:
10.2196/57619 - 发表时间:
2025-01-01 - 期刊:
- 影响因子:6.000
- 作者:
Michael P Williams;Justin Manjourides;Louisa H Smith;Crissi B Rainer;Lisa B Hightow-Weidman;Danielle F Haley - 通讯作者:
Danielle F Haley
Lisa B Hightow-Weidman的其他文献
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{{ truncateString('Lisa B Hightow-Weidman', 18)}}的其他基金
Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN)Scientific Leadership Center; ADMIN SUPPLEMENT
艾滋病毒/艾滋病干预青少年医学试验网络 (ATN) 科学领导中心;
- 批准号:
10855435 - 财政年份:2023
- 资助金额:
$ 1116.21万 - 项目类别:
PrEP Choice: Increasing the Use of HIV Pre-exposure Prophylaxis in an Era of Choices
PrEP 选择:在选择时代增加 HIV 暴露前预防的使用
- 批准号:
10775220 - 财政年份:2022
- 资助金额:
$ 1116.21万 - 项目类别:
PrEP Choice: Increasing the Use of HIV Pre-exposure Prophylaxis in an Era of Choices
PrEP 选择:在选择时代增加 HIV 暴露前预防的使用
- 批准号:
10804710 - 财政年份:2022
- 资助金额:
$ 1116.21万 - 项目类别:
The UNC/Emory Center for Innovative Technology (iTech) across the prevention and care continuum
北卡罗来纳大学/埃默里大学创新技术中心 (iTech) 涵盖预防和护理连续体
- 批准号:
10399185 - 财政年份:2021
- 资助金额:
$ 1116.21万 - 项目类别:
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