Rural Drug Addiction Research Center
农村戒毒研究中心
基本信息
- 批准号:10596483
- 负责人:
- 金额:$ 229.26万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2019
- 资助国家:美国
- 起止时间:2019-04-05 至 2024-03-07
- 项目状态:已结题
- 来源:
- 关键词:AddressAffectAgeAppalachian RegionAreaAttentionBasic ScienceBehavioralBiologicalCenter for Translational Science ActivitiesCessation of lifeChronicClinicalCognitiveCollaborationsCommunitiesCommunity HealthComplexComputer SimulationContractsCountryCoupledDataDedicationsDevelopmentDisciplineDiseaseDisease OutbreaksDrug AddictionDrug abuseDrug usageDrug userEconomicsEmotionalEnsureEnvironmentEpidemiologyEtiologyFacultyFamilyFeedbackFundingGenderGeographyGoalsGrowthHIV InfectionsHealthHealth SciencesHealth StatusHuman BiologyIllicit DrugsImmunologyIncomeIndianaInfectionInfrastructureInjecting drug userInjectionsInstitutionInterdisciplinary StudyInterventionLeadLifeLinkLongitudinal cohort studyMasksMedicalMedical centerMedicineMentorsMethamphetamineMicroscopicNatureNebraskaNervous System PhysiologyNeurologyNeuropharmacologyNeurosciencesOpiate AddictionOutcomeOverdosePathologyPatternPersonsPharmaceutical PreparationsPhysiologicalPilot ProjectsPoliciesProcessReactionRegulationRelapseResearchResearch PersonnelResearch Project GrantsResearch SupportResourcesRuralRural HealthRural drug addictionScientistSexually Transmitted DiseasesSocial EnvironmentSocial NetworkSocial WorkSocietiesStimulantSynapsesTechnical ExpertiseTimeTranslatingUnited StatesUnited States Dept. of Health and Human ServicesUniversitiesUniversity resourcesVirus DiseasesWorkaddictioncareercocaine usecohortcollaborative environmentcombatdrug marketevidence basehealth care availabilityhealth science researchillicit drug usenewspre-clinicalpreventpsychosocialrecruitresearch facilityrural arearural drug userural settingservice organizationservice providerssimulationsocialsocial stigmasocial stressorsoftware developmentsubstance use treatmenturban areaviolence exposurevirtual
项目摘要
PROJECT ABSTRACT
The nature and challenge of illicit drug use in the United States continues to change rapidly, evolving in reaction
to myriad social, economic, and local forces. While drug addiction affects every region of the country, most
information about drug use comes from large urban areas. Emerging data on rural addiction and its harms justify
greater attention. Record drug use, addiction, and overdose rates in rural states, coupled with a dearth of
treatment facilities, point to a rapidly worsening health situation. While health sciences have made considerable
progress in understanding the etiology of drug use and uncovering the link between drug use and its many
associated harms, this promising scientific news has yet to translate to better rural health outcomes. The goal of
this application is to create a sustainable, nationally recognized Center—the Rural Drug Addition Research
Center (RDAR)—dedicated to understanding the causes and impacts of rural drug addiction and its related
challenges and harms. Given the multifactorial nature of addiction, this research must unfold across a continuum
of domains, ranging from the microscopic level of the synapse to larger social contexts. As such, RDAR will draw
on senior investigators and existing resources from the University of Nebraska to mentor early career scientists
in conducting cutting-edge research that addresses rural drug use challenges from multiple angles (i.e., from
synapse to society). For example, initial research projects will focus on the neuroscience of addiction, cognitive
implications of chronic drug use, the relationship between rural drug use and violence exposure, and spatial and
structural simulation of drug-related disease epidemiology. To support these projects, RDAR will found the
Longitudinal Networks Core (LNC), a research core built around cutting-edge cohort tracking and retention
software developed by RDAR senior investigators to offer longitudinal cohort study capacity to RDAR projects.
LNC will recruit and retain a cohort of rural drug users from which RDAR projects will regularly collect data. The
Center will provide dedicated mentoring, professional development, and Center resources to enable early stage
investigators engaged in rural drug addiction research to become independently funded researchers (Aim 1)
while creating a sustainable environment for interdisciplinary research excellence on rural illicit drug use and its
harms (Aim 2). This will lay the groundwork for long-term Center infrastructure (Aim 3) that allows RDAR
researchers to lead efforts to address specific challenges raised by drug addiction in rural settings and develop
appropriate interventions for those settings. RDAR will combine the resources of a nationally recognized
research university (University of Nebraska-Lincoln) and a university-based medical center (University of
Nebraska Medical Center) to create a sustainable research environment, capitalizing on existing collaborations
with local practitioners and state policy and service organizations. Lastly, institutional support in the form of pilot
project funding and new faculty hires in research areas important to RDAR will help ensure the long-term
sustainability of the Center.
项目摘要
美国非法药物使用的性质和挑战继续迅速变化,
无数的社会经济和地方力量虽然吸毒成瘾影响到该国的每一个地区,
有关吸毒的信息来自大城市地区。关于农村成瘾及其危害的新数据证明了
更多的关注。记录药物使用,成瘾,并在农村各州过量的比率,加上缺乏
治疗设施,表明健康状况迅速恶化。虽然健康科学已经取得了相当大的进展,
在了解吸毒病因学和揭示吸毒与其许多方面的
尽管这一充满希望的科学消息与相关危害有关,但尚未转化为更好的农村健康成果。的目标
本申请旨在创建一个可持续发展的、国家认可的中心--农村药物添加研究中心
中心(RDAR)-致力于了解农村吸毒成瘾及其相关问题的原因和影响
挑战和危害。鉴于成瘾的多因素性质,这项研究必须跨越一个连续体展开
从突触的微观层面到更大的社会背景。因此,RDAR将绘制
内布拉斯加大学的高级研究人员和现有资源,以指导早期的职业科学家
在开展从多个角度应对农村毒品使用挑战的前沿研究时(即,从
与社会的联系)。例如,最初的研究项目将集中在成瘾的神经科学,认知,
长期吸毒的影响、农村吸毒与暴力暴露之间的关系以及
药物相关疾病流行病学结构模拟。为了支持这些项目,RDAR将找到
纵向网络核心(LNC),围绕尖端队列跟踪和保留而构建的研究核心
由RDAR高级研究人员开发的软件,为RDAR项目提供纵向队列研究能力。
LNC将招募和保留一批农村吸毒者,RDAR项目将定期收集这些吸毒者的数据。的
中心将提供专门的指导、专业发展和中心资源,
从事农村药物成瘾研究的调查人员成为独立资助的研究人员(目标1)
同时为农村非法药物使用及其
伤害(目标2)。这将为长期中心基础设施(目标3)奠定基础,
研究人员领导努力解决农村吸毒成瘾带来的具体挑战,
对这些情况进行适当干预。RDAR将结合联合收割机的资源,
研究型大学(内布拉斯加大学林肯分校)和大学医学中心(内布拉斯加大学林肯分校)
内布拉斯加州医学中心),以创造一个可持续的研究环境,利用现有的合作
与当地从业者和国家政策和服务组织。最后,以试点形式提供的机构支助
在对RDAR重要的研究领域,项目资金和新的教师招聘将有助于确保长期的
中心的可持续性。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Rick A Bevins其他文献
Rick A Bevins的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Rick A Bevins', 18)}}的其他基金
Understanding and mitigating exacerbated nicotine use resulting from Pavlovianinteroceptive conditioning
了解和缓解巴甫洛夫内感受调节导致的尼古丁使用加剧
- 批准号:
10736191 - 财政年份:2023
- 资助金额:
$ 229.26万 - 项目类别:
National IDeA Symposium of Biomedical Research Excellence - NISBRE
全国 IDeA 生物医学研究卓越研讨会 - NISBRE
- 批准号:
10597964 - 财政年份:2022
- 资助金额:
$ 229.26万 - 项目类别:
Interoceptive conditioning with nicotine: Changes in abuse liability
尼古丁的内感受调节:滥用倾向的变化
- 批准号:
10163151 - 财政年份:2018
- 资助金额:
$ 229.26万 - 项目类别:
Interoceptive conditioning with nicotine: Changes in abuse liability
尼古丁的内感受调节:滥用倾向的变化
- 批准号:
10406337 - 财政年份:2018
- 资助金额:
$ 229.26万 - 项目类别:
Extracellular vesicles, meth relapse and sex differences
细胞外囊泡、冰毒复发和性别差异
- 批准号:
10200728 - 财政年份:2018
- 资助金额:
$ 229.26万 - 项目类别:
相似海外基金
Hormone therapy, age of menopause, previous parity, and APOE genotype affect cognition in aging humans.
激素治疗、绝经年龄、既往产次和 APOE 基因型会影响老年人的认知。
- 批准号:
495182 - 财政年份:2023
- 资助金额:
$ 229.26万 - 项目类别:
Investigating how alternative splicing processes affect cartilage biology from development to old age
研究选择性剪接过程如何影响从发育到老年的软骨生物学
- 批准号:
2601817 - 财政年份:2021
- 资助金额:
$ 229.26万 - 项目类别:
Studentship
RAPID: Coronavirus Risk Communication: How Age and Communication Format Affect Risk Perception and Behaviors
RAPID:冠状病毒风险沟通:年龄和沟通方式如何影响风险认知和行为
- 批准号:
2029039 - 财政年份:2020
- 资助金额:
$ 229.26万 - 项目类别:
Standard Grant
Neighborhood and Parent Variables Affect Low-Income Preschool Age Child Physical Activity
社区和家长变量影响低收入学龄前儿童的身体活动
- 批准号:
9888417 - 财政年份:2019
- 资助金额:
$ 229.26万 - 项目类别:
The affect of Age related hearing loss for cognitive function
年龄相关性听力损失对认知功能的影响
- 批准号:
17K11318 - 财政年份:2017
- 资助金额:
$ 229.26万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Affect regulation and Beta Amyloid: Maturational Factors in Aging and Age-Related Pathology
影响调节和 β 淀粉样蛋白:衰老和年龄相关病理学中的成熟因素
- 批准号:
9320090 - 财政年份:2017
- 资助金额:
$ 229.26万 - 项目类别:
Affect regulation and Beta Amyloid: Maturational Factors in Aging and Age-Related Pathology
影响调节和 β 淀粉样蛋白:衰老和年龄相关病理学中的成熟因素
- 批准号:
10166936 - 财政年份:2017
- 资助金额:
$ 229.26万 - 项目类别:
Affect regulation and Beta Amyloid: Maturational Factors in Aging and Age-Related Pathology
影响调节和 β 淀粉样蛋白:衰老和年龄相关病理学中的成熟因素
- 批准号:
9761593 - 财政年份:2017
- 资助金额:
$ 229.26万 - 项目类别:
How age dependent molecular changes in T follicular helper cells affect their function
滤泡辅助 T 细胞的年龄依赖性分子变化如何影响其功能
- 批准号:
BB/M50306X/1 - 财政年份:2014
- 资助金额:
$ 229.26万 - 项目类别:
Training Grant
Inflamm-aging: What do we know about the effect of inflammation on HIV treatment and disease as we age, and how does this affect our search for a Cure?
炎症衰老:随着年龄的增长,我们对炎症对艾滋病毒治疗和疾病的影响了解多少?这对我们寻找治愈方法有何影响?
- 批准号:
288272 - 财政年份:2013
- 资助金额:
$ 229.26万 - 项目类别:
Miscellaneous Programs