Administrative Core

项目摘要 内布拉斯加大学农村药物成瘾研究中心（RDAR）的行政核心将 协调广泛的调查人员和设施的活动，从而更好地了解 农村地区吸毒所构成的新出现的重大公共卫生挑战。行政目标 核心是领导，实施和支持RDAR向可持续的，国家认可的中心发展 致力于了解农村吸毒成瘾的挑战和危害， 干预措施。为此，行政核心将提供技能、方案领导和 确保中心有效运作所需的基础设施，实现其总体目标， 积极参与新兴的研究机会（目标1）。它还将实施全面的师资队伍 加速早期职业研究人员向独立研究者地位过渡的发展计划， 招募和发展其他人来填补他们的位置（目标2）。行政核心将支持中心附属机构 开展与中心计划重点相关的新颖和合作调查的研究项目 通过进入纵向网络核心（LNC）和实施试点赠款计划， 利用LNC和其他资源进行创新研究（目标3）。在这一过程中，它将为 代表中心成员向NIH提交大型多研究者提案。中心赞助 这些项目将从广泛的学科角度处理农村非法药物使用问题，包括 神经科学、认知和决策、模拟和流行病学以及临床研究。的 行政核心将积极促进四项战略，以促进RDAR项目之间的协同作用， 包括：1）协调跨学科活动，如每月一次的强制性研讨会，每年一次的翻译， 研讨会和合作赠款开发研讨会; 2）为中心提供共同的研究空间 3）促进使用协调一致的数据收集战略;以及4）维持一个 中心会议的定期日程安排，其中合作规划将是一个定期议程项目。通过 这些协调功能，RDAR将使研究人员，博士后研究员，研究生 学生和人员在内布拉斯加大学研究农村吸毒成瘾。中心的领导力 团队将接受外部咨询委员会和内部指导的持续指导， 咨询委员会，委员会将帮助指导中心战略的有效性和可持续性。 RDAR还将建立一支经验丰富的翻译和传播团队，以最大限度地扩大 中心赞助的项目（目标4）。最后，RDAR将通过以下方式实施一个强大的多层次评估计划： 联邦认证的评估员这一整体结构旨在最大限度地提高中心成员的生产力， RDAR的科学进步对这一关键健康问题的影响。

PROJECT ABSTRACT The Administrative Core of the Rural Drug Addiction Research Center (RDAR) at the University of Nebraska will coordinate the activities of a broad range of investigators and facilities, resulting in a better understanding of the critical, emerging public health challenges posed by drug use in rural settings. The goal of the Administrative Core is to lead, implement, and support RDAR’s evolution toward a sustainable, nationally recognized Center dedicated to understanding the challenges and harms of rural drug addiction and developing appropriate interventions. Toward this end, the Administrative Core will provide the skills, programmatic leadership, and infrastructure necessary to ensure the Center functions efficiently, accomplishes its overall goals, and responsively engages emerging research opportunities (Aim 1). It will also implement a comprehensive faculty development plan to accelerate the transition of early career researchers to independent investigator status and recruit and develop others to fill their places (Aim 2). The Administrative Core will support Center-affiliated research projects conducting novel and collaborative investigations related to the Center’s programmatic focus through access to the Longitudinal Networks Core (LNC) and implementation of a pilot grant program to develop innovative research using LNC and other resources (Aim 3). In this process, it will lay the groundwork for the submission of large, multi-investigator proposals to NIH on behalf of Center members. Center-sponsored projects will address the problems of rural illicit drug use from a wide range of disciplinary perspectives, including neuroscience, cognition and decision-making, simulation and epidemiology, and clinical research. The Administrative Core will actively facilitate four strategies for synergy across RDAR projects, including: 1) coordinating interdisciplinary activities such as a mandatory monthly seminar, an annual translation symposium, and collaborative grant development workshops; 2) providing a common research space for Center members and their teams; 3) facilitating the use of a coordinated data collection strategy; and 4) maintaining a regular schedule of Center meetings in which collaboration planning will be a regular agenda item. Through these coordinating functions, RDAR will enable a critical mass of investigators, postdoctoral fellows, graduate students, and personnel to study rural drug addiction at the University of Nebraska. The Center’s Leadership Team will receive ongoing guidance from an External Advisory Committee and an Internal Mentoring and Advisory Committee, committees that will help guide Center strategy toward effectiveness and sustainability. RDAR will also establish an experienced translation and dissemination team to maximize the broader impact of Center-sponsored projects (Aim 4). Finally, RDAR will implement a robust and multilayered evaluation plan by a federally certified evaluator. This overall structure is designed to maximize productivity of Center members and the impact of RDAR’s scientific advances on this critical health issue.