Bioinformatics Advanced Technology Platform (BAT Plat)

生物信息学先进技术平台（BAT平台）

• 批准号: 102512
• 金额: $ 26.51万
• 依托单位: ANALYTICS ENGINES LIMITED
• 依托单位国家: 英国
• 项目类别: Collaborative R&D
• 财政年份: 2015
• 资助国家: 英国
• 起止时间: 2015 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=102512
• 关键词: Bioinformatics; Advanced; Technology; Platform; BAT

This project will build a bioinformatics pipeline on top of the Analytics Engines big data platform enabling:diagnostic/companion diagnostic repositioning, target selection, data-driven drug discovery, data-driven drugrepositioning and pre-clinicial model system alignment.This is enabled by driving the translation of bioinformatics pipelines from ad-hoc, research-drivenenvironments into industrialised clinical processes. In order to achieve this aim, pipelines need to be fullytraceable, repeatable and scalable. Enterprise-grade technologies offering scalable storage and computationare already available, this proposal addresses the challenge of mapping bioinformatics pipelines to thesetechnologies.

该项目将在Analytics Engines大数据平台的基础上建立一条生物信息学管道，实现以下功能：诊断/伴随诊断重新定位、目标选择、数据驱动的药物发现、数据驱动的药物定位和临床前模型系统对齐。这是通过推动生物信息管道从临时的、研究驱动的环境转化为工业化的临床过程来实现的。为了实现这一目标，管道需要完全可追溯、可重复和可扩展。提供可扩展存储和计算的企业级技术已经可用，该提议解决了将生物信息管道映射到这些技术的挑战。