Tidal Breathing Research for Respiratory Disease Management

剑桥呼吸创新有限公司（CRiL）已获得Innovate UK拨款，以完成在广泛呼吸条件下潮汐呼吸监测的研究。CRiL团队开发了一种低成本的个人呼吸监测器，可以测量正常潮汐呼吸中的二氧化碳。他们的目标是开发一系列个人呼吸监测器，帮助患有一系列呼吸系统疾病的人更好地控制自己的病情。CRiL的N-Tidal C由先进的外展式LED二氧化碳传感器驱动，该传感器是与Gas Sensing Solutions合作开发的。虽然它采用了先进的技术，但这种医疗设备非常容易使用，因为它不需要强制过期。CRiL的低成本医疗设备在正常潮汐呼吸中每秒精确测量二氧化碳浓度超过50次。CRiL的N-Tidal C最近被用于COPD患者的一项重要的探索性临床研究。呼吸记录显示，COPD患者在COPD加重前48小时左右开始出现呼吸记录的明显变化。CRiL团队正在研究他们的技术是否可以预测哮喘发作，并帮助改善一系列呼吸系统疾病的药物依从性和疾病管理。CRiL创新技术的开发此前得到了Innovate UK和SBRI Healthcare的支持。

Cambridge Respiratory Innovations Limited (CRiL) has been awarded an Innovate UK grant to complete research into tidal breathing monitoring across a wide range of respiratory conditions. The CRiL team have developed a low-cost personal respiratory monitor which measures the CO2 in normal tidal breathing. Their goal is to develop a range of personal respiratory monitors to help people who suffer from a range of respiratory diseases to better manage their condition. CRiL's N-Tidal C is powered by an advanced expitaxially-grown LED CO2 sensor developed in partnership with Gas Sensing Solutions. Although it uses advanced technology, the medical device is very easy to use, since it requires no forced expiration. CRiL's low-cost medical device accurately measures CO2 concentrations more than 50 times per second in normal tidal breathing. CRiL's N-Tidal C has recently been used in a significant exploratory clinical study with patients with COPD. The breathing records demonstrate clear changes in the breath record start to occur in COPD about 48 hours before a COPD exacerbation. The CRiL team are investigating whether their technology can predict attacks in asthma and help to improve medicines adherence and disease management across a range of respiratory conditions. The development of CRiL's innovative technology has been supported previously by both Innovate UK and SBRI Healthcare.