Tidal Breathing Research for Respiratory Disease Management

呼吸系统疾病管理的潮汐呼吸研究

• 批准号: 102977
• 金额: $ 27.11万
• 依托单位: CAMBRIDGE RESPIRATORY INNOVATIONS LIMITED
• 依托单位国家: 英国
• 项目类别: Feasibility Studies
• 财政年份: 2017
• 资助国家: 英国
• 起止时间: 2017 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=102977
• 关键词: Tidal; Breathing; Research; Respiratory; Disease

Cambridge Respiratory Innovations Limited (CRiL) has been awarded an Innovate UK grant to complete research into tidal breathing monitoring across a wide range of respiratory conditions. The CRiL team have developed a low-cost personal respiratory monitor which measures the CO2 in normal tidal breathing. Their goal is to develop a range of personal respiratory monitors to help people who suffer from a range of respiratory diseases to better manage their condition. CRiL's N-Tidal C is powered by an advanced expitaxially-grown LED CO2 sensor developed in partnership with Gas Sensing Solutions. Although it uses advanced technology, the medical device is very easy to use, since it requires no forced expiration. CRiL's low-cost medical device accurately measures CO2 concentrations more than 50 times per second in normal tidal breathing. CRiL's N-Tidal C has recently been used in a significant exploratory clinical study with patients with COPD. The breathing records demonstrate clear changes in the breath record start to occur in COPD about 48 hours before a COPD exacerbation. The CRiL team are investigating whether their technology can predict attacks in asthma and help to improve medicines adherence and disease management across a range of respiratory conditions. The development of CRiL's innovative technology has been supported previously by both Innovate UK and SBRI Healthcare.

剑桥呼吸创新有限公司(CRIL)获得了英国创新基金，以完成对各种呼吸条件下的潮气呼吸监测的研究。CRIL团队开发了一种低成本的个人呼吸监测仪，可以测量正常潮气呼吸中的二氧化碳。他们的目标是开发一系列个人呼吸监测仪，以帮助患有一系列呼吸道疾病的人更好地管理自己的病情。CRIL的N型潮汐C由与气体传感解决方案公司合作开发的先进的外延生长的LED二氧化碳传感器提供动力。虽然它使用了先进的技术，但医疗设备非常容易使用，因为它不需要强制过期。CRIL的低成本医疗设备在正常潮气呼吸时每秒准确测量二氧化碳浓度超过50次。CRIL的N-TdaC最近已被用于COPD患者的一项重要的探索性临床研究。呼吸记录表明，呼吸记录在COPD恶化前48小时开始发生明显的变化。CRIL团队正在调查他们的技术是否可以预测哮喘的发作，并帮助改善一系列呼吸道疾病的用药依从性和疾病管理。CRIL创新技术的开发此前得到了Innovate UK和SBRI Healthcare的支持。