DIGITAL BREAST SPECIMEN RADIOGRAPHY FOR IMPROVED BIOPSY

用于改进活检的数字化乳房标本放射成像

• 批准号: 2111438
• 负责人: Emre Toker
• 金额: $ 10万
• 依托单位: MEDOPTICS CORPORATION
• 依托单位国家: 美国
• 财政年份: 1995
• 资助国家: 美国
• 起止时间: 1995-03-01 至 1995-08-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2111438
• 关键词: biomedical equipment development; biopsy; breast neoplasm /cancer diagnosis; breast neoplasms; breast surgery; charge coupled device camera; image enhancement; radiography; telemedicine

The aim of this proposal is to develop a compact, filmless, electronic x- ray imaging system for high resolution breast specimen radiography. This device is intended for use in the operating room for rapid radiography of excisional breast specimens, and in radiology for needle core biopsy procedures. This approach will enable the surgeon and radiologist to view the image on a computer monitor simultaneously during telephone consultation. It is anticipated that this method will save extremely valuable operating room time and will virtually eliminate the need for the surgeon to make a decision without the immediate availability of a specimen radiograph. The proposed research will investigate the use of a CCD with 1024x1024 pixel resolution, which will detect the light emission from a fine detail x-ray intensifying screen in response to an x-ray beam directed from a micro focus x-ray source. One configuration will be a lens-coupled approach, where the x-ray intensifying screen is optically coupled to a CCD using fast lenses, the other configuration will use fiber optic coupling between the intensifying screen and the CCD. The system will be designed to provide superior image quality as compared to conventional film-based specimen radiography systems. PROPOSED COMMERCIAL APPLICATION: 8,000 to 10,000 breast biopsies are performed each year in the United States. Currently, no dedicated filmless specimen radiography system is commercially available. Given the advantages of filmless radiography, especially for small field-of-view applications, we expect strong commercial interest in this technology.

该提案的目的是开发一种紧凑、无胶片、电子 x- 用于高分辨率乳腺标本射线照相的射线成像系统。 这 设备旨在用于手术室中的快速射线照相 切除乳房标本，以及放射学中的针芯活检 程序。 这种方法将使外科医生和放射科医生能够查看 打电话时图像同时显示在计算机显示器上 咨询。 预计此方法将极大地节省 宝贵的手术室时间，几乎消除了对手术的需要 外科医生在没有立即可用的情况下做出决定 射线照片标本。 拟议的研究将调查使用 具有 1024x1024 像素分辨率的 CCD，可检测光发射 来自精细细节 X 射线增感屏对 X 射线束的响应 由微焦点 X 射线源引导。 一种配置是 透镜耦合方法，其中 X 射线增感屏是光学的 使用快速镜头耦合到 CCD，其他配置将使用光纤 增感屏和CCD之间的光耦合。 系统 与相比，将被设计为提供卓越的图像质量 传统的基于胶片的标本射线照相系统。 拟议的商业应用：8,000 至 10,000 个乳房活检 每年都会在美国演出。目前还没有专门的无胶片 样本射线照相系统是市售的。 鉴于 无胶片放射线摄影的优点，特别是对于小视场 应用程序，我们预计对该技术有强烈的商业兴趣。