DIGITAL BREAST SPECIMEN RADIOGRAPHY FOR IMPROVED BIOPSY

用于改进活检的数字化乳房标本放射成像

• 批准号: 2111438
• 负责人: Emre Toker
• 金额: $ 10万
• 依托单位: MEDOPTICS CORPORATION
• 依托单位国家: 美国
• 财政年份: 1995
• 资助国家: 美国
• 起止时间: 1995-03-01 至 1995-08-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2111438
• 关键词: biomedical equipment development; biopsy; breast neoplasm /cancer diagnosis; breast neoplasms; breast surgery; charge coupled device camera; image enhancement; radiography; telemedicine

The aim of this proposal is to develop a compact, filmless, electronic x- ray imaging system for high resolution breast specimen radiography. This device is intended for use in the operating room for rapid radiography of excisional breast specimens, and in radiology for needle core biopsy procedures. This approach will enable the surgeon and radiologist to view the image on a computer monitor simultaneously during telephone consultation. It is anticipated that this method will save extremely valuable operating room time and will virtually eliminate the need for the surgeon to make a decision without the immediate availability of a specimen radiograph. The proposed research will investigate the use of a CCD with 1024x1024 pixel resolution, which will detect the light emission from a fine detail x-ray intensifying screen in response to an x-ray beam directed from a micro focus x-ray source. One configuration will be a lens-coupled approach, where the x-ray intensifying screen is optically coupled to a CCD using fast lenses, the other configuration will use fiber optic coupling between the intensifying screen and the CCD. The system will be designed to provide superior image quality as compared to conventional film-based specimen radiography systems. PROPOSED COMMERCIAL APPLICATION: 8,000 to 10,000 breast biopsies are performed each year in the United States. Currently, no dedicated filmless specimen radiography system is commercially available. Given the advantages of filmless radiography, especially for small field-of-view applications, we expect strong commercial interest in this technology.

该提议的目的是开发一个紧凑的，无电影的，电子X- 高分辨率乳房标本射线照相的射线成像系统。 这 设备旨在在手术室中用于快速射线照相 切除乳房标本和针对针核活检的放射学 程序。 这种方法将使外科医生和放射科医生能够查看 电话时同时在计算机监视器上的图像 咨询。 预计这种方法将极大地节省 宝贵的手术室时间，实际上将消除对 外科医生做出决定，而无需立即提供 标本X光片。 拟议的研究将调查使用 CCD具有1024x1024像素分辨率，它将检测到光发射 从一个细节X射线增强屏幕，以响应X射线梁 由微聚焦X射线源指向。 一种配置将是 镜头耦合方法，其中X射线加剧屏幕是光学的 使用快速镜头结合到CCD，另一种配置将使用光纤 加强屏幕和CCD之间的光学耦合。 系统 与 常规的基于膜的标本射线照相系统。 拟议的商业应用：8,000至10,000个乳房活检是 每年在美国进行。目前，没有专门的无电影 标本射线照相系统可商购。 鉴于 无电影射线照相的优点，特别是对于小型视野 应用程序，我们预计对这项技术的商业兴趣很大。