Super-resolution dual-energy dental CT based on distributed x-ray source and photon counting detector
Super-resolution dual-energy dental CT based on distributed x-ray source and photon counting detector
批准号:
10258444
负责人:
Emre Toker
金额:
$22.17万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2021
资助国家:
美国
项目状态:
已结题
起止时间:
2021-09-21 至 2023-09-21
关键词:
3-DimensionalAddressAdvanced DevelopmentAlgorithmsAnatomyAnimalsAnodesBenchmarkingCadaverClinicalComputer-Aided DesignComputer-Assisted ManufacturingDentalDental CareDental ClinicsDental EducationDental General PracticeDentistryDetectionDiagnosisDiagnostic ImagingDiagnostic radiologic examinationEffectivenessElectronicsEvaluation StudiesFlying body movementFreezingGeometryGoalsImageImaging TechniquesImaging technologyImmuneImplantInferiorKnowledgeLesionLocationModelingMorphologic artifactsMotionNoiseOperative Surgical ProceduresOpticsOralOral PathologyOutcomeOutcomes ResearchPatient CarePatient-Focused OutcomesPatientsPerformancePhasePhotonsPlayProceduresProductivityQuality of CareRadiation exposureRehabilitation therapyResearch PersonnelResolutionRoentgen RaysRoleRotationSaintsScanningSmall Business Technology Transfer ResearchSourceSpottingsStarvationStructureSystemTechnologyThree-Dimensional ImageThree-Dimensional ImagingTimeTissuesTubeUniversitiesX-Ray Computed Tomographybaseclinical implementationcommercial applicationcone-beam computed tomographydensitydesigndetectorhigh resolution imagingimage reconstructionimaging modalityimaging systemimprovedinferior alveolar nerveinnovationinterestnovelphoton-counting detectorpoint of careprototypereconstructionresearch clinical testingsoft tissuestem
中文摘要
摘要
英文摘要
ABSTRACT
With cone-beam CT's introduction in dentistry, dental clinicians could not only have profound knowledge of
oral pathology but could also enhance the access to a detailed view of the underlying structures and their
relations. Dental CBCT could be justified for presurgical diagnosis, preoperative planning and preoperative
transfer for oral implant rehabilitation. The image quality of CBCT, however, is suboptimal and suffers from
strong image artifacts stemming from excessive x-ray scattering, limited detector performance. Spatial
resolution, the most important parameter objectively defining image quality, is insufficient for many dental
applications where the fine details often have to be depicted. We will develop and validate a novel dental
imaging system that not only fundamentally eliminates the image quality problems and but also can produce
superior image resolution in 3D images. The super-resolution dual-energy Tetrahedron Beam CT (TBCT)
employs a novel multi-pixel thermionic emission x-ray (MPTEX) source with wobbling focal spots as well as
an energy-resolved photon-counting detector (PCD). TBCT scans the patient with a stack of fan beams that
have a very low scatter-to-primary ratio (SPR); The PCD detector can count x-ray photons without
electronics noises, thus can reduce radiation exposure and dental artifacts due to photon starvation; The
dual-energy capacity of PCD further eliminates beam-hardening artifacts and supports material
decomposition; The flying focal spots and Time-delay-integration (TDI) detection will compensate gantry
motion, and super-resolution 3D images can be reconstructed with optics-model based iterative image
reconstruction (IIR). Super-resolution dental TBCT will fit in the gap of high-performance 3D imaging in
dentistry, allow further advancing the productivity and quality of care in dental practice. The following
specific aims have been designed to accomplish this goal: Aim 1: Develop MPTEX source with variable
focal spot size and location; Aim 2: To develop and validate a super-resolution dental TBCT benchtop
imaging system.
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Sentinel lymph node biopsy system for breast cancer
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财政年份:1995
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负责人:Emre Toker
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依托单位:
海外基金