Proof of Market and Feasibility Study for Point-of Care SAMBA Respiratory Multiplex Test

呼吸道感染每年导致全球约425万人死亡。在英国，许多患者因疑似流感感染而访问他们的家庭医生，大量患者住院治疗。由于流感感染与包括普通感冒在内的许多其他感染有许多共同之处，因此患者经常被错误地对待。目前，没有简单准确的即时检测（POC）可用于快速诊断感染，医生依赖症状进行诊断。世界卫生组织已将发展呼吸道病毒感染的准确POC检测列为优先事项。这种测试的发展可能会改变医生评估和治疗急性呼吸道感染患者的方式。快速诊断导致呼吸道感染的病毒将允许给予正确的治疗，从而降低高危人群的发病率和死亡率，从而为患者提供更好的治疗，并为医疗保健提供者节省资源和成本。然而，在开发此类测试之前，诊断专家了解临床医生对测试的要求至关重要。本项目的目标是：1）通过确定临床和健康经济学要求，了解诊断呼吸道感染的POC检测市场; 2）确定开发用于DRW CE认证桑巴舞平台的检测的可行性。DRW将利用这些信息为开发用于诊断呼吸道病毒感染的创新性多重诊断POC检测提供信息，并降低其财务风险。

Respiratory infections cause around 4.25 million deaths worldwide every year. In the UK, many patients visit their GP for a suspected flu infection and large numbers are hospitalised. Since a flu infection shares many symtoms with a number of other infections, including the common cold, patients are often treated incorrectly. Currently, there is no simple accurate point-of-care test (POC) that can be used to quickly diagnose infections, and doctors rely on symptoms for diagnosis. The World Health Organisation has listed development of accurate POC tests for respiratory viral infections as a priority. Development of such a test may transform the way doctors assess and treat patients with acute respiratory infections. Rapid diagnosis of the virus causing the respiratory infections would allow the correct treatment to be administered, thereby reducing morbidity and mortality in at-risk groups, leading to better treatment for patients and resource and cost savings for healthcare providers. However, before such as test is developed it is critical that diagnostic manufactureres understand the clinicians requirement for the test. The objective of this project is to 1) generate understanding of the market for a POC test to diagnose respiratory infections by determining the clinical and health enconomic requirements and 2) determine the feasibility of developing the test for use on DRW's CE marked SAMBA platform. DRW will use this information to inform the development of, and reduce the financial risk of, developing an innovative multiplex diagnostic POC test for the diagnosis of respiratory viral infections.