Extraction and purification of a novel hemocyanin through implementation of new technologies.

通过实施新技术提取和纯化新型血蓝蛋白。

• 批准号: 104524
• 金额: $ 13.03万
• 依托单位: MIKOTA LTD
• 依托单位国家: 英国
• 项目类别: Feasibility Studies
• 财政年份: 2018
• 资助国家: 英国
• 起止时间: 2018 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=104524
• 关键词: Extraction; purification; novel; hemocyanin; through

"Mikota Ltd is looking to build on early investigative work into hemocyanin from the blood of the slipper limpet, an invasive, non-native species to UK shores. Having successfully identified hemocyanin proteins in the limpets as well as drafted and tested a basic extraction protocol, Mikota now aims to scale up production of this hemocyanin to a commercial level. As well as scaling up production, we will focus on perfecting a storage method for the finished product that will preserve the viability of the hemocyanin for long term storage.This work is being undertaken in collaboration with Cardiff University, with their work packages being led by Dr Mark Young and Prof Thomas Wirth. In support of Cardiff University work, and Mikota's helping young people prepare for the work place, Mikota is funding 3 Professional Year students to be placed at Cardiff University.By scaling up this process Mikota will deliver a new sustainable medical grade hemocyanin sourced locally from an invasive species to the UK, that has significant value in the anticancer, vaccine and immunotherapy markets."

“Mikota Ltd正在寻求建立对拖鞋帽贝血液中血蓝蛋白的早期调查工作，这是一种入侵英国海岸的非本土物种。在成功鉴定了帽贝中的血蓝蛋白，并起草和测试了基本的提取方案后，Mikota现在的目标是将这种血蓝蛋白的生产规模扩大到商业水平。除了扩大生产规模，我们还将专注于完善成品的储存方法，以保持血蓝蛋白的长期储存活力。这项工作正在与卡迪夫大学合作进行，他们的工作包由Mark Young博士和托马斯沃思教授领导。为了支持卡迪夫大学的工作，以及Mikota帮助年轻人为工作做好准备，Mikota正在资助3名专业年学生进入卡迪夫大学。通过扩大这一过程，Mikota将向英国提供一种新的可持续医疗级血蓝蛋白，该血蓝蛋白来自当地的入侵物种，在抗癌，疫苗和免疫治疗市场上具有重要价值。"