Novel technology to purify viral vectors free of empty capsids for gene therapy use at manufacturing scale

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Gene therapy has formed one of the most advanced medical technology in the modern precision medicine area. It has shown some unique advantages in curing certain diseases. There is a growing demand of high quality viral medicines to be manufactured with efficient and cost-effective methods. This Research Project proposes a highly efficient chromatography bead technology to elegantly remove host-cell-based impurities and virus-related impurities to obtain high quality viral materials at processing scale.