Digital technology to addresses onset of neurodegenerative disorders in an ageing society.

“随着年龄的增长，越来越多的全球人口出现记忆问题、抑郁、时空迷失或逻辑推理能力下降。这些发病症状可能导致早期神经退行性疾病，如痴呆。随着这些疾病的发展，脑电波活动减弱。目前的药物治疗有严重的副作用，而非药物治疗，如大脑训练应用程序，不是针对患者的，也没有经过临床试验的验证。我们的目标是通过开发一种独特的个性化，临床验证的技术来解决这一全球性问题，该技术通过应用治疗游戏和机器学习来改善患者的认知大脑功能。好处：(1)非侵入性；(2)提高心智能力；(3)抑郁减轻；(4)能提供早期诊断；(5)确保患者的独立性；(6)减少对国民保健服务的依赖，改善英国经济；(6)将加强英国在神经系统疾病研究方面的领导地位。”

"There is an increasing proportion of the global population with memory problems, depression, space-time disorientation or decreased logical reasoning with aging. These onset symptoms may lead to early-stage neurodegenerative disorders e.g. dementia. As these conditions progress, the brainwave activities decline.Present drug treatments come with severe side-effects, and non-drug treatments i.e. brain training apps are not patient specific and are not validated through clinical trials.We aim to address this global issue by developing a unique-personalised, clinically validated technology which improves a patient's cognitive brain function through application of therapeutic games and machine learning.Benefits:Benefits: (1) non-invasive; (2) improved mental ability; (3) reduced depression; (4) can provide early diagnosis; (5) ensures patient independence; (6) reduced reliance upon NHS and improves UK economy; and (6) will strengthen UK as leader in neurological disorder research."