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Improving bovine in vitro embryo production through follicular flushing and next generation embryo culture

通过卵泡冲洗和下一代胚胎培养提高牛体外胚胎产量

基本信息

批准号：
105142
负责人：
金额：
$ 66.01万
依托单位：
PARAGONVET LIMITED
依托单位国家：
英国
项目类别：
Collaborative R&D
财政年份：
2019
资助国家：
英国
起止时间：
2019 至无数据
项目状态：
已结题

来源：
https://gtr.ukri.org/projects?ref=105142
关键词：
Improving bovine vitro embryo production

项目摘要

"Significant advances are being made in technologies associated with cattle breeding that seek to improve production efficiency, animal health and welfare whilst minimising environmental impact. These advances are motivated, in part, by the increased global demand for milk and beef, and a public desire that this is achieved in a sustainable manner. This project seeks to develop in vitro embryo production as a tool to facilitate enhanced genetic improvement. Specifically, it will manufacture new equipment to recover more oocytes (eggs) per donor-cow cycle (i.e. via ovarian-follicular flushing) and to create a new generation of improved media for the culture of embryos within the laboratory. Collectively, these technical innovations will increase embryo production efficiency and lead to higher pregnancy rates following transfer. This, in turn, will lead to increased rates of genetic improvement by breeding from only the best cows.Cattle breeders are eager to engage with and utilise this technology in order to improve the health, productivity and efficiency of their herds. This will enable farmers to produce and rear animals more suited to their farming system with greater precision. This will, in turn, reduce demand for resources such as animal feed, fertilisers and pesticides, and a reduction in animal waste and greenhouse gas emissions."

“与养牛相关的技术正在取得重大进展，这些技术旨在提高生产效率、动物健康和福利，同时最大限度地减少对环境的影响。这些进步的部分原因是全球对牛奶和牛肉的需求增加，以及公众希望以可持续的方式实现这一目标。该项目旨在开发体外胚胎生产，作为促进增强遗传改良的工具。具体而言，它将制造新设备，以在每个供体牛周期（即通过卵巢卵泡冲洗）回收更多的卵母细胞（卵子），并在实验室内创建新一代改良的胚胎培养培养基。总的来说，这些技术创新将提高胚胎生产效率，并提高移植后的妊娠率。这反过来又会通过只从最好的奶牛中育种来提高遗传改良的速度。养牛者渴望参与并利用这项技术来改善牛群的健康、生产力和效率。这将使农民能够更精确地生产和饲养更适合其耕作系统的动物。这反过来将减少对动物饲料、化肥和杀虫剂等资源的需求，并减少动物废物和温室气体排放。"