VecoB - A novel spatial insect repellent

VecoB - 一种新型空间驱虫剂

• 批准号: 105240
• 金额: $ 24.96万
• 依托单位: ARCTECH INNOVATION LIMITED
• 依托单位国家: 英国
• 项目类别: Feasibility Studies
• 财政年份: 2019
• 资助国家: 英国
• 起止时间: 2019 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=105240
• 关键词: VecoB; novel; spatial; insect; repellent

"More than 50% of the global population are at risk of vector-borne diseases such as malaria, Dengue fever, Yellow fever, Zika and Lyme disease, causing 1 billion cases and 1 million deaths per year. Environmental changes are causing an increase in the range and abundance of disease vectors such as mosquitoes and ticks worldwide. The socio-economic cost of these diseases is significant: Zika virus caused GDP losses of ~$18BN in Latin America and the Caribbean in just 2 years (UNDP,2017). Annually, the UK has 481,000 A&E attendances for insect bites, costing the NHS £59.6 million per year (£124 per visit). For many vector-borne diseases there are no available vaccines and drug resistance is increasing, with insect control and repellent products essential to prevent disease outbreak. Given the rise in resistance to insecticides and emerging evidence of resistance to existing repellents (e.g. DEET), amongst other environmental and health concerns, novel solutions are urgently needed to tackle growing arthropod-related public health problems.To address this challenge, Vecotech has identified a novel, natural, plant-derived repellent which has proven to be topically and spatially effective in feasibility tests against several key species of mosquitos, midges and ticks. Building on this work, this project aims to develop an advanced formulation that provides stable protective efficacy and can be incorporated into a biodegradable material for use as a best-in-class wearable or household repellent product with a minimal environmental footprint. Compared to current wearable repellent devices, which have a protective efficacy of <2 weeks, Vecotech's solution will show long-lasting protective efficacy over 3-5 months, representing a \>5x increase on current state-of-the-art.Success in this project will enable Vecotech to bring a range of market leading wearable and home-based spatial repellent products to the market, with global exploitation potential within the insect-repellent market forecasted to be worth £5.39 billion by 2026, increasing company revenue and profit to support continued growth and competitiveness. The VecoB solution is anticipated to contribute to reductions in global morbidity/mortality rates of vector-borne diseases, aligned with the World Health Organisation's recommendations for elevated insect-control measures to prevent vector-borne epidemics. This will help to reduce the economic costs of lost working days and medical costs associated with vector-borne diseases. As a naturally-derived product, VecoB-based products will be safe, have a high public acceptance and will selectively target medically important vectors with no risk to the health of humans, wildlife or the broader environment."

“全球50%以上的人口面临疟疾、登革热、黄热病、寨卡病毒和莱姆病等病媒传播疾病的风险，每年造成10亿例病例和100万人死亡。环境变化正在导致世界范围内蚊子和蜱虫等病媒的范围和数量增加。这些疾病的社会经济成本是巨大的：寨卡病毒在短短两年内导致拉丁美洲和加勒比地区的GDP损失约180亿美元（联合国开发计划署，2017年）。英国每年有48.1万名因昆虫叮咬而就诊的急诊患者，NHS每年为此花费5960万英镑（每次就诊124英镑）。对于许多病媒传播的疾病，没有可用的疫苗，耐药性正在增加，控制昆虫和驱避产品对于防止疾病暴发至关重要。鉴于对杀虫剂的抗药性上升和对现有驱蚊剂（如避蚊胺）的抗药性的新证据，以及其他环境和健康问题，迫切需要新的解决办法来解决日益严重的与节肢动物有关的公共卫生问题。为了应对这一挑战，Vecotech已经确定了一种新型的、天然的、植物来源的驱蚊剂，在针对几种主要蚊子、蠓和蜱虫的可行性测试中，这种驱蚊剂在局部和空间上都是有效的。在这项工作的基础上，该项目旨在开发一种先进的配方，提供稳定的保护功效，并可纳入可生物降解材料中，作为一流的可穿戴或家用驱蚊产品，对环境的影响最小。与目前的可穿戴式驱蚊设备相比，其保护效果小于2周，而Vecotech的解决方案将显示长达3-5个月的持久保护效果，比目前最先进的产品提高了50倍。该项目的成功将使维科科技能够将一系列市场领先的可穿戴和家用空间驱蚊产品推向市场，预计到2026年，全球驱蚊市场的开发潜力将达到53.9亿英镑，增加公司收入和利润，以支持持续增长和竞争力。预计VecoB解决方案将有助于降低全球病媒传播疾病的发病率/死亡率，这符合世界卫生组织关于加强昆虫控制措施以预防病媒传播流行病的建议。这将有助于减少工作日损失的经济成本和与病媒传播疾病有关的医疗费用。作为一种天然衍生产品，基于vecob的产品将是安全的，具有很高的公众接受度，并将选择性地针对医学上重要的病媒，而不会对人类、野生动物或更广泛的环境健康构成风险。”