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A novel vascular stem cell product ANGICYTE for regenerative medicine

A novel vascular stem cell product ANGICYTE for regenerative medicine
用于再生医学的新型血管干细胞产品ANGICYTE
批准号:
105380
负责人:
金额:
$26.92万
依托单位:
依托单位国家:
英国
项目类别:
Study
财政年份:
2020
资助国家:
英国
项目状态:
已结题
起止时间:
2020 至 --

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中文摘要
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英文摘要
"VascVersa (Versatile Vascular Stem Cells for Regenerative Medicine)Cardiovascular diseases are the top cause of death worldwide. There is an urgent need to find new treatments to repair damaged blood vessels as current approaches are not optimal. At VascVersa, we are committed to develop innovative regenerative medicine, and we have optimised a consistent way to manufacture highly pure vascular stem cells from a sample of blood. Our unique method of generation produces a stem cell therapy product ANGICYTE, of top quality with higher purity and superior growth capacity, when compared to other available cell products.These vascular stem cells can be grown up in our laboratory to provide large numbers for treatment. As all tissue repair requires blood supply, ANGICYTE can be harnessed to target areas of blood vessel injury and promote repair of damaged blood vessels. We have experimental evidence that our Vascular stem cells can be used as a cellular therapy promoting new blood vessel formation. We are developing a novel cell therapy product ANGICYTE for regenerative medicine. In the first phase, we will use ANGICYTE to target wound healing as it was a key area of demand identified in our market research (through the ICURe programme) and includes diabetic ulcers, pressure ulcers, burns, wounds, and chronic non-healing ulcers; however, ANGICYTE can also be applied to other vascular diseases in the heart, brain, and limbs, and this will be the focus of our second phase. This Innovate UK grant will provide much needed start-up funding to allow us to spin out our company, develop our technology into a clinical grade product and meet with regulatory agencies that will guide the future development of these stem cells to effectively treat patients."
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  • 批准号:
    82371605
  • 项目类别:
    面上项目
  • 资助金额:
    46.00万元
  • 批准年份:
    2023
  • 负责人:
    蒋君涛
  • 依托单位:
尾加压素II介导血管外膜氧化应激促进血管重构的作用研究
  • 批准号:
    81141003
  • 项目类别:
    专项基金项目
  • 资助金额:
    10.0万元
  • 批准年份:
    2011
  • 负责人:
    丁文惠
  • 依托单位:
核素靶向示踪肿瘤新生血管作用位点研究
  • 批准号:
    81071183
  • 项目类别:
    面上项目
  • 资助金额:
    32.0万元
  • 批准年份:
    2010
  • 负责人:
    王荣福
  • 依托单位:
硫化氢通过核转录因子-kB信号途径调节高血压大鼠血管平滑肌细胞增殖的研究
  • 批准号:
    81070212
  • 项目类别:
    面上项目
  • 资助金额:
    33.0万元
  • 批准年份:
    2010
  • 负责人:
    金红芳
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