ENDOCRINE ASPECTS OF HUMAN NEOPLASIA

人类肿瘤的内分泌方面

• 批准号: 2142544
• 负责人: SHLOMO MELMED
• 金额: $ 74.66万
• 依托单位: CEDARS-SINAI MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 1991
• 资助国家: 美国
• 起止时间: 1991-07-01 至 1997-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2142544
• 关键词: ENDOCRINE; ASPECTS; HUMAN; NEOPLASIA

项目成果

A novel mechanism for isolated central hypothyroidism: inactivating mutations in the thyrotropin-releasing hormone receptor gene.

孤立性中枢性甲状腺功能减退症的新机制：促甲状腺激素释放激素受体基因的失活突变。

• DOI: 10.1210/jcem.82.5.3918
• 发表时间: 1997
• 期刊: The Journal of clinical endocrinology and metabolism.
• 作者: Collu,R;Tang,J;Castagne,J;Lagace,G;Masson,N;Huot,C;Deal,C;Delvin,E;Faccenda,E;Eidne,KA;VanVliet,G
• 通讯作者: VanVliet,G

Hypothalamic and pituitary leukemia inhibitory factor gene expression in vivo: a novel endotoxin-inducible neuro-endocrine interface.

体内下丘脑和垂体白血病抑制因子基因表达：一种新型内毒素诱导神经内分泌界面。

• DOI: 10.1210/endo.137.7.8770918
• 发表时间: 1996
• 期刊: Endocrinology.
• 作者: Wang,Z;Ren,SG;Melmed,S
• 通讯作者: Melmed,S

Disrupted murine leukemia inhibitory factor (LIF) gene attenuates adrenocorticotropic hormone (ACTH) secretion.

• DOI: 10.1210/endo.137.7.8770940
• 发表时间: 1996-07
• 期刊: Endocrinology
• 影响因子: 4.8
• 作者: S. Akita;J. Malkin;S. Melmed

Expression of three somatostatin receptor subtypes in pituitary adenomas: evidence for preferential SSTR5 expression in the mammosomatotroph lineage.

垂体腺瘤中三种生长抑素受体亚型的表达：促乳腺激素谱系中 SSTR5 优先表达的证据。

• DOI: 10.1210/jcem.79.3.7521350
• 发表时间: 1994
• 期刊: The Journal of clinical endocrinology and metabolism
• 作者: Greenman,Y;Melmed,S
• 通讯作者: Melmed,S

Heparin-binding secretory transforming gene (hst) facilitates rat lactotrope cell tumorigenesis and induces prolactin gene transcription.

肝素结合分泌转化基因（hst）促进大鼠催乳素细胞肿瘤发生并诱导催乳素基因转录。

• DOI: 10.1172/jci118388
• 发表时间: 1996
• 期刊: The Journal of clinical investigation.
• 作者: Shimon,I;Huttner,A;Said,J;Spirina,OM;Melmed,S
• 通讯作者: Melmed,S