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IN VIVO/IN VITRO WEAR PERFORMANCE OF POSTERIOR COMPOSITE

后复合材料的体内/体外磨损性能

基本信息

批准号：
2130490
负责人：
KARL-JOHAN M SODERHOLM
金额：
$ 21.07万
依托单位：
UNIVERSITY OF FLORIDA
依托单位国家：
美国
项目类别：
财政年份：
1991
资助国家：
美国
起止时间：
1991-08-01 至 1998-07-31
项目状态：
已结题

项目摘要

The objective of this proposal is to explore the principal wear mechanisms of experimental dental composites. Eight experimental light-cured composites which contain either bisGMA/TEGDMA or UEDMA/-TEGDMA as matrices, 60 vol% of quartz or barium filler particles, and two different silanization procedures will be prepared, analyzed, and tested under in vivo and in vitro conditions. After an initial characterization of the two resin systems, the degree of conversion of the materials will be determined. In addition, qualitative and quantitative analyses of silanization effectiveness will be performed. These studies will be followed by in vitro evaluations of compressive strength, flexural strength, toughness and wear of the composite systems. The in vitro wear evaluation will be conducted using a wear testing machine (deGee et a/., 1986) and a standard metallographic polishing machine (Jorgensen, 1980). Mechanical properties and wear rate will be determined for three aging conditions: 1) dry storage in a desiccator (37 degrees C), 2) in distilled water (37 degrees C), and 3) in artificial saliva (37 degrees C) for periods up to three years. Filler leaching rates and diffusion coefficients of water molecules from distilled water and artificial saliva in these materials will also be determined. After ensuring that the eight experimental composites have fulfilled the requirements of ADA Specification No. 27, in vivo wear resistance of the composites will be evaluated. Two in vivo investigations will be conducted using 64 patients at the University of Florida and 64 patients at the University of Leuven, Belgium. One American dentist and one Belgian dentist will each treat 32 patients in each country. Class I restorations will be placed in maxillary and mandibular first molars. The material loss due to wear will be determined using three different evaluation techniques after 6, 12, 24, and 36 months. With these clinical evaluations, it will be possible to determine: 1) whether differences in diet among different population groups result in significant differences in wear rate, 2) whether restorations made by different dentists are likely to result in differences in clinical wear performance, and 3) whether differences in wear evaluation methods for the clinical specimens result in significantly different wear results. It will also be determined whether strong correlations exist between any of the investigated properties (including in vitro wear) and the clinical wear rate. In addition, experimental materials containing 60 vol% of filler with mean particle diameters of approximately 0.2, 1, 5 and 10 mu-m will be investigated regarding their in vitro wear resistance. The objective of this part of the study is to determine the influence of filler spacing on wear rate.

这项建议的目的是探索主要磨损实验性牙科复合材料的作用机制。八个实验性的光固化复合材料，含有双GMA/TEGDMA或 UEDMA/-TEGDMA作为基质，60vol%的石英或钡填充颗粒，和两种不同的硅烷化程序将被准备，分析，和在体内和体外条件下进行测试。在首字母之后表征了两种树脂体系的转化率。材料将被确定。此外，质的和将对硅烷化效果进行定量分析。在这些研究之后，将对压力进行体外评估复合材料系统的强度、弯曲强度、韧性和磨损。体外磨损评估将使用磨损测试进行机器(Degee et a/.，1986)和标准金相抛光机器(Jorgensen，1980)。机械性能和磨损率将是在三种老化条件下确定：1)干燥器(37)中的干燥存储摄氏度)，2)在蒸馏水(37摄氏度)中，以及3)在人工唾液(37摄氏度)，持续时间长达三年。填料浸出蒸馏水中水分子的扩散速率和扩散系数这些材料中的人工唾液也将被检测出来。在确保八个实验复合材料完成后 ADA规范第27号的要求，活体耐磨性将对复合材料进行评估。两项体内研究将是使用佛罗里达大学的患者和患者进行了调查在比利时鲁汶大学。一名美国牙医和一名比利时牙医将在每个国家治疗32名患者。第I类修复体将被放置在上颌和下颌第一磨牙上。磨损造成的材料损失将使用三种不同的方法来确定 6个月、12个月、24个月和36个月后评估技术。有了这些临床评估，将有可能确定：1)是否不同人群的饮食差异导致磨损率有显著差异，2)修复体是否由不同的牙医可能会导致临床佩戴的不同性能，以及3)磨损评估方法是否存在差异临床标本的磨损结果明显不同。还将确定是否存在强相关性，研究的性能(包括体外磨损)和临床应用磨损率。此外，实验材料中含有60%体积%的填料和大约0.2、1、5和10微米的平均颗粒直径将是研究了它们的体外耐磨性。的目标是这一部分的研究是为了确定填料间距对磨损率。